Results 11 to 20 of about 214,320 (304)

C1-inhibitor/C1-inhibitor antibody complexes in acquired angioedema due to C1-inhibitor deficiency [PDF]

Orphanet Journal of Rare Diseases, 2023
Background Autoantibodies against C1-inhibitor (C1-INH-Ab) have a diagnostic value in acquired angioedema due to C1-inhibitor deficiency (C1-INH-AAE), even though antibodies can circulate in complexes, which can be undetectable by proven methods. Our aim
Zsofia Polai, Erika Kajdacsi, Laszlo Cervenak, Zsuzsanna Balla, Szabolcs Benedek, Lilian Varga, Henriette Farkas   +6 more
doaj   +4 more sources

Edema of the Scrotum and Penile Shaft: An Uncommon Initial Presentation of Acquired Angioedema With Low C1-Inhibitor [PDF]

Case Reports in Urology
Acquired angioedema with low C1-inhibitor (AAE-C1-INH) is a rare disorder characterized by an acquired deficiency in the C1 esterase inhibitor (C1-INH). This case report describes a 79-year-old patient presenting to the emergency department for painless ...
Meghan V. Matheny, Timothy Craig, Joseph Y. Clark   +2 more
doaj   +2 more sources

C1-inhibitor to prevent intracerebral hemorrhage-related secondary brain injury [PDF]

Fluids and Barriers of the CNS
Background Preclinical studies indicate that the systemic application of C1-inhibitor, clinically used to treat hereditary angioedema, reduces secondary brain injury after ischemic stroke. This study assessed the effect of C1-inhibitor on secondary brain
Kevin Akeret, Bart R. Thomson, Subhajit Ghosh, Marc Nolte, Urs Fischer, Rok Humar, Luca Regli, Dominik J. Schaer, Michael Hugelshofer, Raphael M. Buzzi   +9 more
doaj   +2 more sources

Editorial: C1 inhibitor deficiency and angioedema [PDF]

Frontiers in Allergy, 2022
Henriette Farkas, Anastasios E. Germenis, Hilary Longhurst   +2 more
doaj   +2 more sources

Short-term Prophylaxis for Delivery in Pregnant Women with Hereditary Angioedema with Normal C1-Inhibitor [PDF]

Revista Brasileira de Ginecologia e Obstetrícia, 2021
Objective To verify the efficacy of short-term prophylaxis for vaginal or cesarean section childbirth with plasma-derived C1-inhibitor concentrate in pregnant women. They should have hereditary angioedema (HAE) and normal plasma C1-inhibitor.
Caroline Guth de Freitas Batista de Moraes, Liya Regina Mikami, Lilian Pereira Ferrari, João Bosco Pesquero, Herberto José Chong-Neto, Nelson Augusto Rosario Filho   +5 more
doaj   +2 more sources

Retrospective Evaluation of Patients with Angioedema Treated with C1 Inhibitors in an Emergency Department

Eurasian Journal of Emergency Medicine, 2022
Aim:We aimed first to investigate patients who received C1 inhibitor therapy in the emergency department (ED). The patients’ complaints, examination findings, length of stay in the ED and whether the patients were treated with anything other than C1 ...
Sercan Yalçınlı, Selahattin Kıyan, Funda Karbek Akarca   +2 more
doaj   +1 more source

Psychological processes in the experience of hereditary angioedema in adult patients: an observational study

Orphanet Journal of Rare Diseases, 2021
Background Hereditary angioedema associated to C1 inhibitor deficiency (C1-INH-HAE) is a pathological condition characterized by episodes of subcutaneous swelling and it is frequently associated with discomfort and social impairment of the patients, due ...
Livia Savarese, Maria Bova, Assunta Maiello, Angelica Petraroli, Ilaria Mormile, Mauro Cancian, Riccardo Senter, Andrea Zanichelli, Giuseppe Spadaro, Maria Francesca Freda   +9 more
doaj   +1 more source

Utility of Biomarkers for Postpartum Hemorrhage Transfusion Requirements Relating to Amniotic Fluid Embolism

Clinical and Experimental Obstetrics & Gynecology, 2023
Background: We aimed to evaluate the utility of C1 esterase inhibitor, squamous cell carcinoma antigen, and complements C3 and C4 in the prediction of fresh frozen plasma transfusion requirements in postpartum hemorrhage and characterize the involvement ...
Ryuichi Shimaoka, Tomomi Shiga, Ken-Ichirou Morishige   +2 more
doaj   +1 more source

Quantification of C1 esterase inhibitor in human serum by enzyme-linked immunosorbent assay: Correlation with turbidimetric immunoassay

Медицинская иммунология, 2023
C1 inhibitor of serine proteases (C1-INH) performs a regulatory function in the complement system and vascular permeability. Deficiency of C1-INH leads to various forms of angioedema, including hereditary angioedema (HAE).
N. P. Gorbunov, A. V. Zhakhov, I. N. Gorbunova, A. M. Milichkina, I. V. Drozd, A. V. Gubanova, E. M. Danilova, R. N. Kuznecova, T. V. Savin, A. G. Burtseva, N. V. Pigareva, A. M. Ischenko, Areg A. Totolian   +12 more
doaj   +1 more source

Hereditary angioedema (HAE) in children and adolescents : a consensus on therapeutic strategies [PDF]

, 2012
Hereditary angioedema due to C1 inhibitor (C1 esterase inhibitor) deficiency (types I and II HAE-C1-INH) is a rare disease that usually presents during childhood or adolescence with intermittent episodes of potentially life-threatening angioedema ...
Aberer, Werner, Eberl, Wolfgang, Faßhauer, Maria, Kreuz , Wolfhart, Kurnik, Karin, Kühne, Thomas, Magerl, Markus, Martinez Saguer, Inmaculada, Meyer-Olson, Dirk, Späth, Peter J., Staubach-Renz, Petra, Wahn, Volker   +11 more
core   +1 more source