Results 21 to 30 of about 878,820 (240)

Optimum Use of Acute Treatments for Hereditary Angioedema: Evidence-Based Expert Consensus

Frontiers in Medicine, 2018
Acute treatment of hereditary angioedema due to C1 inhibitor deficiency has become available in the last 10 years and has greatly improved patients’ quality of life.
Hilary Longhurst
doaj   +1 more source

Successful C1 inhibitor short-term prophylaxis during redo mitral valve replacement in a patient with hereditary angioedema

Journal of Cardiothoracic Surgery, 2010
Hereditary angioedema is characterized by sudden episodes of nonpitting edema that cause discomfort and pain. Typically the extremities, genitalia, trunk, gastrointestinal tract, face, and larynx are affected by attacks of swelling.
Coleman Suzanne, Bernstein Jonathan A, Bonnin Arturo J   +2 more
doaj   +1 more source

Successful treatment of post-pericardiotomy syndrome via C1 inhibitor replacement therapy in a hereditary angioedema patient with Marfan syndrome

The Turkish Journal of Pediatrics, 2023
Background. Hereditary angioedema with C1 inhibitor deficiency (HAE-C1INH) is caused by dysfunctional C1-INH protein due to mutations in the SERPING1 gene encoding C1-INH.
Ezgi Topyıldız, Handan Duman Şenol, Figen Gülen, Esen Demir, Nihal Mete Gökmen   +4 more
doaj   +1 more source

Long-term Prophylaxis with Androgens in the management of Hereditary Angioedema (HAE) in emerging countries

Orphanet Journal of Rare Diseases, 2022
Hereditary angioedema (HAE) is a rare autosomal dominant genetic disease characterized by repetitive subcutaneous or submucosal angioedema, activation of the kinin system, and increased vascular permeability.
Yinshi Guo, Huanping Zhang, He Lai, Huiying Wang, Herberto J. Chong-Neto, Solange O. R. Valle, Rongfei Zhu   +6 more
doaj   +1 more source

Recombinant and Plasma-Purified Human C1 Inhibitor for the Treatment of Hereditary Angioedema

World Allergy Organization Journal, 2010
Background Agents for prophylaxis of hereditary angioedema (HAE) have been available in the United States for several decades, but their usefulness is limited by side effects and they cannot be used at all in some patients.
Michael M Frank, MD
doaj   +1 more source

Acquired Form of Angioedema of the Head and Neck Related to a Deficiency in C1-Inhibitor: A Case Report with a Review of the Literature

Case Reports in Otolaryngology, 2012
Angioedema related to a deficiency in the C1-inhibitor protein is characterized by its lack of response to therapies including antihistamine, steroids, and epinephrine. In the case of laryngeal edema, mortality rate is approximately 30 percent. The first
Bassel Hallak, Propser Konu, Florian Lang, Christian Simon, Philippe Monnier   +4 more
doaj   +1 more source

Characterization of carbohydrate chains of C1-inhibitor and of desialylated C1-inhibitor [PDF]

, 1992
Carbohydrate chains of C1-inhibitor were identified with a binding assay using different lectins. Lectins from Sambucus nigra (SNA) and Maackia amurensis (MAA) that are specific for sialic acids bound to C1-inhibitor. Lectin from Datura strantonium (DSA)
Oeyvind L. Schoenberger, Schoenberger, Oeyvind L.   +1 more
core   +1 more source

Modulation of C1-Inhibitor and Plasma Kallikrein Activities by Type IV Collagen

International Journal of Biomaterials, 2012
The contact system of coagulation can be activated when in contact with biomaterials. As collagen is being tested in novel biomaterials in this study, we have investigated how type IV collagen affects plasma kallikrein and C1-inhibitor.
Sriram Ravindran, Marc Schapira, Philip A. Patston   +2 more
doaj   +1 more source

Serial change of C1 inhibitor in patients with sepsis: a prospective observational study

Journal of Intensive Care, 2018
Background C1 inhibitor (C1-INH), which belongs to the superfamily of serine protease inhibitors, regulates the complement system and also the plasma kallikrein-kinin, fibrinolytic, and coagulation systems.
Tomoya Hirose, Hiroshi Ogura, Hiroki Takahashi, Masahiro Ojima, Kang Jinkoo, Youhei Nakamura, Takashi Kojima, Takeshi Shimazu   +7 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source