Results 21 to 30 of about 214,320 (304)

Angioedema due to acquired C1-inhibitor deficiency: spectrum and treatment with C1-inhibitor concentrate

open access: yesOrphanet Journal of Rare Diseases, 2019
Background Acquired angioedema due to C1-inhibitor (C1-INH) deficiency (AAE-C1-INH) is a serious condition that may result in life-threatening asphyxiation due to laryngeal edema. It is associated with malignant B-cell lymphoma and other disorders.
Konrad Bork   +2 more
doaj   +1 more source

Study on separation and purification process of C1 esterase inhibitor

open access: yesZhongguo shuxue zazhi, 2022
Objective To study the technology of separating and purifying C1 esterase inhibitor (C1-INH) by using the waste washing liquid as raw materia during the preparation of human prothrombin complex (PCC) l.
Jiabin XU   +4 more
doaj   +1 more source

C1 inhibitor deficiency: 2014 United Kingdom consensus document [PDF]

open access: yes, 2015
C1 inhibitor deficiency is a rare disorder manifesting with recurrent attacks of disabling and potentially life-threatening angioedema. Here we present an updated 2014 United Kingdom consensus document for the management of C1 inhibitor-deficient ...
Ashworth, F   +11 more
core   +3 more sources

C1-Inhibitor protects from focal brain trauma in a cortical cryolesion mice model by reducing thrombo-inflammation

open access: yesFrontiers in Cellular Neuroscience, 2014
Traumatic brain injury (TBI) induces a strong inflammatory response which includes blood-brain barrier damage, edema formation and infiltration of different immune cell subsets.
Christiane eAlbert-Weissenberger   +12 more
doaj   +1 more source

The effects of continuous venovenous hemofiltration on coagulation activation [PDF]

open access: yes, 2006
INTRODUCTION: The mechanism of coagulation activation during continuous venovenous hemofiltration (CVVH) has not yet been elucidated. Insight into the mechanism(s) of hemostatic activation within the extracorporeal circuit could result in a more rational
Bouman, Catherine S. C.   +9 more
core   +1 more source

Optimum Use of Acute Treatments for Hereditary Angioedema: Evidence-Based Expert Consensus

open access: yesFrontiers in Medicine, 2018
Acute treatment of hereditary angioedema due to C1 inhibitor deficiency has become available in the last 10 years and has greatly improved patients’ quality of life.
Hilary Longhurst
doaj   +1 more source

Secreted phospholipases A2 in hereditary angioedema with C1-inhibitor deficiency [PDF]

open access: yes, 2018
BackgroundHereditary angioedema (HAE) caused by deficiency (type I) or dysfunction (type II) of the C1 inhibitor protein (C1-INH-HAE) is a disabling, potentially fatal condition characterized by recurrent episodes of swelling. We have recently found that
Andrea Zanichelli   +16 more
core   +3 more sources

Activation of coagulation factor XI, without detectable contact activation in dengue haemorrhagic fever [PDF]

open access: yes, 2001
A prospective cohort study was performed in 50 patients with dengue haemorrhagic fever (DHF) to determine the potential role of the contact activation system and factor XI activation (intrinsic pathway) in the coagulation disorders in DHF.
Bajzar   +29 more
core   +2 more sources

Successful C1 inhibitor short-term prophylaxis during redo mitral valve replacement in a patient with hereditary angioedema

open access: yesJournal of Cardiothoracic Surgery, 2010
Hereditary angioedema is characterized by sudden episodes of nonpitting edema that cause discomfort and pain. Typically the extremities, genitalia, trunk, gastrointestinal tract, face, and larynx are affected by attacks of swelling.
Coleman Suzanne   +2 more
doaj   +1 more source

Risk of angioedema following invasive or surgical procedures in HAE type I and II : the natural history [PDF]

open access: yes, 2013
Background: Hereditary angioedema (HAE), caused by deficiency in C1-inhibitor (C1-INH), leads to unpredictable edema of subcutaneous tissues with potentially fatal complications.
Aygören-Pürsün, Emel   +4 more
core   +1 more source

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