Results 81 to 90 of about 119,425 (295)

Mixed‐Metal Promotion in a Manganese‐Molybdenum Oxynitride as Catalyst to Integrate C─C and C─N Coupling Reactions for the Direct Synthesis of Acetonitrile from Syngas and Ammonia

Advanced Materials, EarlyView.
Transition metal oxy/carbo‐nitrides show great promise as catalysts for sustainable processes. A Mn‐Mo mixed‐metal oxynitride attains remarkable performance for the direct synthesis of acetonitrile, an important commodity chemical, via sequential C─N and C─C coupling from syngas (C1) and ammonia (N1) feedstocks.
M. Elena Martínez‐Monje, Wilson Henao, Tania Rodenas, Patricia Concepción, Virginia Pérez Dieste, Alexander Missyul, Giovanni Agostini, Gonzalo Prieto   +7 more
wiley   +1 more source

Plasma levels of C1- inhibitor complexes and cleaved C1- inhibitor in patients with hereditary angioneurotic edema [PDF]

, 1990
C1- inhibitor (C1(-)-Inh) catabolism in plasma of patients with hereditary angioneurotic edema (HANE) was assessed by measuring the complexes formed by C1(-)-Inh with its target proteases (C1-s, Factor XIIa, and kallikrein) and a modified (cleaved ...
M Cugno, M. Cicardi, D. Frangi, A. Eerenberg, A. Agostoni, D Frangi, A Agostoni, E. Hack, M Cicardi, M. Cugno, A Eerenberg, J. Nuijens, J Nuijens, E Hack   +13 more
core   +1 more source

Dexime: A Selectively Enzyme‐Degradable Hydrogel for Protein Therapeutic Release

Advanced Materials, EarlyView.
A dextrin‐oxime hydrogel (dexime) is produced using ketone or aldehyde modified dextrin and tetra‐oxyamine modified poly(ethylene glycol). The rheological and mechanical properties of dexime are tunable. Dexime is injectable, cytocompatible, hydrolytically stable, and selectively degradable by α‐amylase.
Quinton E. A. Sirianni, Nitzan Letko Khait, Adam Forman, Edward A. Armstrong, Karim Fouad, Molly S. Shoichet   +5 more
wiley   +1 more source

Personalized biological treatment with lanadelumab in a patient with recurrent attacks of hereditary angioedema

Alergologia Polska
Hereditary angioedema (HAE) is an autosomal dominantly inherited disease caused by deficiency of C1 esterase inhibitor protein type 1 (about 85% of patients with HAE-C1-INH) or type 2 oedema (about 15% of patients with HAE-C1-INH) by C1 inhibitor ...
Artur Gęsicki, Maciej F. Kozlowski, Karolina Żurawska, Weronika Ossowska, Jakub Sikora, Szymon Dyguś, Iwona Poziomkowska-Gęsicka   +6 more
doaj   +1 more source

Turning Unpredictable Biomolecule Adsorption to Controlled Corona Formation: Focus on Carbon Nanomaterials

Advanced Materials, EarlyView.
Controlling the protein corona formation onto carbon nanomaterials (CNMs) enhances their functionalities as platforms for cancer theranostics. Here, we reviewed the effects of the intrinsic and acquired properties of CNMs on protein corona formation, the consequent biological and toxicological outcomes, and the strategies to reshape corona formation ...
Yajuan Zou, Yalei Hu, Jie Yu, Naoki Komatsu, Yuta Nishina, Alberto Bianco   +5 more
wiley   +1 more source

Effect of mutations within the coding region of C1-INH gene on protein function in families with HAE

, 2005
C1 esterase inhibitor (C1-INH) is a serine protease inhibitor (serpin). Serpins are a superfamily of proteins that fold into a conserved structure and utilize a unique suicide substrate-like inhibitory mechanism.
M. Cicardi, E. Pappalardo, S. Caccia, L. Maggioni   +3 more
core  

C1 inhibitor regulates OSCS-induced kallikrein activity.

, 2012
(A) Normal human plasma, plasma depleted of C1 inhibitor, plasma depleted of factor XII, and plasma depleted of both C1 inhibitor and factor XII, were incubated with chondroitin sulfate A (CSA) or over sulfated chondroitin sulfate A (OSCS). The effect of
Trina Chen (171196), Zhao-Hua Zhou (171194), Kamalpreet Arora (171198), Steven Kozlowski (171203), Kenneth Hyams (171201)   +4 more
core   +1 more source

Targeted Modulation of d‐Band Center in MoS2 Interlayer With n‐Type Co/Fe Dopants Accelerating Sulfur Reaction Kinetics in Lithium‐Sulfur Batteries

Advanced Materials, EarlyView.
A targeted modulation of the MoS2 electronic structure is achieved via substitutional n‐type Co/Fe co‐doping. This strategy triggers S‐mediated d‐p hybridization, optimizing the binding affinity with polysulfides to establish a volcano‐shaped relationship between the d‐band center and catalytic activity.
Junhyuk Ji, Sangyeon Won, Jaehyeong Yu, Nuri Moon, Dongwoo Kim, Junbeom Maeng, Won Bae Kim   +6 more
wiley   +1 more source

The physician and hereditary angioedema friend or foe: 62-year diagnostic delay and iatrogenic procedures

Allergy, Asthma & Clinical Immunology, 2018
Background Hereditary angioedema due to C1 inhibitor deficiency (C1-INH-HAE) is a rare autosomal dominant disease characterized by episodes of acute subcutaneous swelling, and/or recurrent severe abdominal pain.
Anna Valerieva, Marco Cicardi, James Baraniuk, Maria Staevska   +3 more
doaj   +1 more source

Molecular Genetics of C1 Inhibitor

Immunobiology, 1998
More than 100 different C1 inhibitor gene mutations have been described in hereditary angioedema (HAE) patients. Sixty-nine mutations have been reported in patients with the quantitative C1 inhibitor defect (type 1 HAE) in two recent large-scale studies. These changes were found distributed over all exons and exon/intron boundaries.
openaire   +2 more sources