Results 71 to 80 of about 62,354 (276)

Clinical impact of complement (C1q, C3d) binding De Novo donor-specific HLA antibody in kidney transplant recipients. [PDF]

PLoS ONE, 2018
INTRODUCTION:Complement binding activity of donor-specific HLA antibodies (DSA) has been suggested as a new tool to stratify immunologic risk in kidney transplantation (KT).
Hyeyoung Lee, Eunhee Han, Ae-Ran Choi, Tae Hyun Ban, Byung Ha Chung, Chul Woo Yang, Yeong Jin Choi, Eun-Jee Oh   +7 more
doaj   +1 more source

Evolution of Multivalent Aptamer Corona for High‐Throughput Multiplexed Detection of Multiple Cancers

Advanced Science, EarlyView.
A multivalent aptamer corona is evolved via established ProteoFish‐SELEX (systematic evolution of ligands by exponential enrichment) for high‐throughput multiplexed detection of multiple cancers. Clinical validation using multivalent aptamer corona demonstrated high accuracy and specificity in multiplexed detection of ovarian, lung, and colorectal ...
Mengjie Wang, Baichuan Jin, Xin Dai, Haozhe Huang, Qiqi Liu, Jianqing Zhu, Haixing Ju, Qixun Chen, Yongmei Song, Weihong Tan, Yuan Liu   +10 more
wiley   +1 more source

MINI-REVIEW: SYSTEMIC LUPUS ERYTHEMATOSUS AND DEFICIENCIES OF EARLY COMPONENTS OF THE COMPLEMENT CLASSICAL PATHWAY

Frontiers in Immunology, 2016
The complement system plays an important role in the innate and acquired immune response against pathogens. It consists of more than 30 proteins found in soluble form or attached to cell membranes. Most complement proteins circulate in inactive forms and
Lourdes eIsaac, Ana Catarina Lunz Macedo
doaj   +1 more source

Complement protein C1q interacts with DC-SIGN via its globular domain, and thus may interfere with HIV-1 transmission [PDF]

, 2016
Dendritic Cells (DCs) are the most potent antigen presenting cells capable of priming naïve T cells. Its C-type lectin receptor, DC-SIGN, regulates a wide range of immune functions.
Appelmelk, Balzarini, Balzarini, Banapour, Banki, Bashirova, Bouhlal, Bouhlal, Boyer, Burton, Caffrey, Caparros, Curtis, Delibrias, Delibrias, den Dunnen, Ebenbichler, Fausther-Bovendo, Gaboriaud, Gadjeva, Gadjeva, Geijtenbeek, Geijtenbeek, Geijtenbeek, Geijtenbeek, Ghebrehiwet, Ghebrehiwet, Gras, Gringhuis, Hoorelbeke, Hosszu, Kang, Kang, Kishore, Kittlesen, Kojouharova, Lang, Leavy, Lozach, Maeda, Manches, Marschang, Martinez, Matthews, McLachlan, Mitchell, Mohan, Nayak, Nayak, Pednekar, Pinter, Pohlmann, Prabagar, Roumenina, Sarkar, Solder, Szabo, Tacnet-Delorme, Thielens, Thielens, Vegh, Wang   +61 more
core   +1 more source

Emerging and novel functions of complement protein C1q

Frontiers in Immunology, 2015
Complement protein C1q, the recognition subcomponent of the classical pathway, performs a diverse range of complement and non-complement functions. It can bind various ligands derived from self, non-self and altered-self and modulate the functions of ...
Lubna eKouser, Shanmuga Priyaa Madhukaran, Abhishek eShastri, Anuvinder eSaraon, Janez eFerluga, Maha eAl-Mozaini, Uday eKishore   +6 more
doaj   +1 more source

A multicenter, prospective, observational study to determine association of mesangial C1q deposition with renal outcomes in IgA nephropathy

Scientific Reports, 2021
It was reported that histopathologic lesions are risk factors for the progression of IgA Nephropathy (IgAN). The aim of this study was to investigate the relationships between mesangial deposition of C1q and renal outcomes in IgAN.
Li Tan, Yi Tang, Gaiqin Pei, Zhengxia Zhong, Jiaxing Tan, Ling Zhou, Dongmei Wen, David Sheikh-Hamad, Wei Qin   +8 more
doaj   +1 more source

Further remarks on the "Smith is Huq" condition [PDF]

, 2014
We compare the 'Smith is Huq' condition (SH) with three commutator conditions in semi-abelian categories: first an apparently weaker condition which arose in joint work with Bourn and turns out to be equivalent with (SH), then an apparently equivalent ...
Martins-Ferreira, Nelson, Van der Linden, Tim   +1 more
core   +1 more source

Glomerular deposition of C1q and anti-C1q antibodies in mice following injection of antimouse C1q antibodies

Clinical and Experimental Immunology, 2003
SUMMARY Anti-C1q autoantibodies are present in the serum of patients with different autoimmune diseases such as systemic lupus erythematosus (SLE). The occurrence of these autoantibodies correlates with renal involvement. In the present study we examined whether injection of rabbit antimouse C1q antibodies in mice leads to deposition in ...
L A, Trouw, M A, Seelen, J M G J, Duijs, H, Benediktsson, C, Van Kooten, M R, Daha   +5 more
openaire   +3 more sources

Full-House Nephropathy Without Lupus Manifesting During Acute Kidney Allograft Rejection: A Case Report. [PDF]

Clin Case Rep
ABSTRACT Kidney transplantation increases the survival rate of end‐stage renal disease patients; however, acute rejection and glomerulonephritis, such as the uncommon non‐lupus full‐house nephropathy (NLFHN), can lead to graft dysfunction. NLFHN exhibits a characteristic lupus immunofluorescence pattern in the absence of systemic lupus features, which ...
Pourlak T, Farnood F.
europepmc   +2 more sources

Association of Circulating Anti-HLA Donor-Specific Antibodies and Their Characteristics, including C1q-Binding Capacity, in Kidney Transplant Recipients with Long-Term Renal Graft Outcomes [PDF]

, 2023
Michał Gniewkiewicz, Katarzyna Czerwińska, Katarzyna Zielniok, Magdalena Durlik   +3 more
openalex   +1 more source