Results 111 to 120 of about 38,034 (262)
Do factors secreted from synovial fibroblasts affect the differentiation of C2C12 cells?
, 2011 The Wnt signalling pathway plays a key role within muscle differentiation. Wnt3a, Wnt5a, and DKK1 all have pivotal roles within this pathway. It’s hypothesised that due to their role within the Wnt pathway, Wnt3a, Wnt5a, and DKK1 will affect the ...
McCabe, Emma Louise
core
Fish Scales: A Multifunctional Biomaterial from Nature
ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.Fish scales demonstrate nature's solution to impact protection through overlapping multilayered architecture. This biological design combines mineralized surfaces with collagen networks to achieve both flexibility and fracture resistance. The structural principles inspire advanced protective materials and biomedical implants, where damage tolerance ...
Liyao Dong, Xiaojie Sun, Xiguang Chen
wiley +1 more source
Equine Veterinary Journal, EarlyView.Abstract Background Lamellar endoplasmic reticulum (ER) stress occurs in hyperinsulinemia‐associated and sepsis‐related laminitis. Adiponectin is associated with reduced laminitis risk and inhibits ER stress in other species. Objectives To induce ER stress in ex vivo equine lamellar cells using pharmacological agents.
Marine A. Barnabé +6 more
wiley +1 more source
C2C12 myotubes replicate prions to high levels of infectivity.
, 2013 (A) C2C12 myotubes infected with RML were collected at 4 or 15 days post infection by scraping in PBS, centrifuging and resuspending in 500 µL of water. 30 µL of this cell material was inoculated intracranially into weanling C57Bl/6 mice. A statistically
Debbie McKenzie (16350) +7 more
core +1 more source
Fbxl21 deletion leads to MYOZ1 accumulation and inhibits C2C12 myoblast differentiation.
, 2022 (A) MYOZ1 staining of control and Fbxl21 KO C2C12 cells in myoblasts (differentiation Day 0) and myotubes (Day 6). Right panels: MYOZ1 fluorescence intensity quantification at day 0 and day 6.
Collin M. Douglas (14305221) +11 more
core +1 more source
Zhongguo shiyan zhenduanxue, 2009 目的研究17β-雌二醇对小鼠成肌细胞C2C12细胞钙离子通道的影响,探讨7β-雌二醇对C2C12细胞的作用。方法应用全细胞膜片钳技术记录不同浓度的17β-雌二醇作用下C2C12细胞钙离子通道的变化。结果67%的C2C12细胞可记录到钙离子电流。在不同浓度17β-雌二醇的作用下,30 mol.L-1组及20 mol.L-1组可引起C2C12细胞钙离子电流明显增大 ...
冷冰, 刘志刚, 蒋维海
doaj
A compendium of extracellular vesicle biogenesis inhibitors: From bench to bedside
Interdisciplinary Medicine, EarlyView.This review explores a decade of research on extracellular vesicles (EVs), detailing their biogenesis and roles in health and disease. It emphasizes EVs' relevance for potential medical applications covering various conditions such as cancer, neurodegeneration, inflammation, and infectious diseases, bridging experimental findings with clinical ...
Stefano Vecchione +2 more
wiley +1 more source
Conessine treatment induces autophagosome formation in C2C12 cells.
, 2016 (A) C2C12 cells were transfected with a plasmid encoding GFP-LC3 and cells were treated with either mock or conessine (10 μM). (B) Conessine treatment increased the level of LC3-II and p62.
Minsu Jang (2817730) +8 more
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Mass Spectrometry Insights Into Post‐Translational Modifications in Extracellular Vesicles
Mass Spectrometry Reviews, EarlyView.ABSTRACT Extracellular vesicles (EVs) are membrane‐enclosed structures secreted by virtually all living cells, serving as essential mediators of intercellular communication in both physiological and pathological processes. There is growing interest in their potential applications as biomarkers, therapeutic targets, and drug delivery systems, which ...
Dávid Virág +5 more
wiley +1 more source
Analysis of autophagy in C2C12 and MURF2 RNAi cells.
, 2013 (A) Endogenous p62 was detected in C2C12 cells and MURF2 RNAi myoblasts (Diff. 0h) and in cells differentiated for 48h. Cells were immunostained with anti-p62 antibody and analyzed by confocal microscopy. Scale Bar: 10 µm.
Giuseppe Baldacci (372167) +6 more
core +1 more source