Results 101 to 110 of about 38,034 (262)
SMRT protein is strongly expressed in the later phase of differentiation process of C2C12 cells.
, 2022 (A) The series of time points (day 0–5) of mRNA expression levels of Smrt during the differentiation process of C2C12-WT cell were assessed by qPCR (n = 3). (B) The series of time points (day 0–5) of protein expressions of SMRT during the differentiation
Hiroaki Shimizu (440570) +8 more
core +1 more source
Journal of Pharmacological Sciences, 2008 To obtain compounds that promote glucose uptake in muscle cells, the novel cell lines A31-IS derived from Balb/c 3T3 A31 and C2C12-IS from mouse myoblast C2C12 were established.
Kenji Hayata +2 more
doaj +1 more source
Animal Research and One Health, EarlyView.Integrated transcriptomic and functional analyses identify CDKN1A as a direct target of ZBED6 in Bama pigs. ZBED6 knockout relieves transcriptional repression of CDKN1A, thereby promoting myogenic differentiation and skeletal muscle development.
Yitian Ma +8 more
wiley +1 more source
Biotechnology and Bioengineering, EarlyView.ABSTRACT Cultivated meat production requires efficient differentiation of muscle progenitor cells into myotubes without relying on animal‐derived serum, which poses ethical and scalability challenges. This study aimed to develop a chemically defined, serum‐free medium optimized for bovine satellite cell differentiation.
Aysenaz Tavsanli +3 more
wiley +1 more source
miR-1 targets Pax7 during C2C12 differentiation.
, 2012 (A) Predicted target sites, A and B, of miR-1 in the 3′UTR of mouse Pax7. (B) A luciferase reporter plasmid was generated by cloning a ∼800 bp region of Pax7 3′UTR encompassing both site A and B downstream of the luciferase (Luc) reporter gene.
Liang Zhou (85586) +8 more
core +1 more source
Biochemistry and Biophysics ReportsSarcopenia is an age-related muscle atrophy characterized by decreased muscle mass and function. However, potential treatments to alleviate sarcopenia remain limited.
Pooreum Lim +5 more
doaj +1 more source
Scientific Reports, 2020 Phosphoenolpyruvate carboxykinase (PEPCK) is a gluconeogenic enzyme with a cytosolic (Pck1/PEPCK-C) and mitochondrial (Pck2/PEPCK-M) isoform. Here we investigate the effect of 3-mercaptopicolinic acid (3-MPA), a PEPCK inhibitor, on C2C12 muscle cells. We
Madelaine C. Brearley +4 more
doaj +1 more source
Microbial Hydrolysates as Amino Acid Source in Cell Culture Media for Cellular Agriculture
Biotechnology and Bioengineering, EarlyView.ABSTRACT The high cost of cultivation media remains one of the barriers to the commercialization of cultivated meat. Current serum‐free media reduce reliance on fetal bovine serum but only achieve modest cost savings. Especially at larger scales (> 20 m3), pharmaceutical‐grade amino acids and recombinant proteins remain major cost drivers.
Jelle C. Hoek +3 more
wiley +1 more source
Sphingomyelinase promotes atrophy in C2C12 myotubes
The FASEB Journal, 2011 Chronic heart failure, sepsis, and cancer chemotherapy lead to skeletal muscle atrophy. In all these conditions, the activity of sphingomyelinase (SMase) in the plasma is elevated. SMase has been shown to activate proteolytic pathways in non‐muscle cells.
Peter Jerome Schwagerl +4 more
openaire +1 more source
BMEMat, EarlyView.Schematic illustration of preparation of injectable H/G@Co@miR‐206 hydrogel for efficient skeletal muscle regeneration in cardiotoxin‐induced skeletal muscle injury SD rat model. Abstract The effective treatment of acute skeletal muscle injuries remains challenging, necessitating therapeutic strategies that concurrently reestablish vascular perfusion ...
Zhengzhe Han +9 more
wiley +1 more source