Results 31 to 40 of about 38,034 (262)
Myostatin Stimulates, Not Inihibits, C2C12 Myoblast Proliferation [PDF]
Endocrinology, 2014 The immortal C2C12 cell line originates from dystrophic mouse thigh muscle and has been used to study the endocrine control of muscle cell growth, development, and function, including those actions regulated by myostatin. Previous studies suggest that high concentrations of recombinant myostatin generated in bacteria inhibit C2C12 proliferation and ...
Buel D, Rodgers +5 more
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Effect of Couette Type of Shear Stress Field with Axial Shear Slope on Deformation and Migration of Cell: Comparison Between C2C12 and HUVEC [PDF]
Journal of Systemics, Cybernetics and Informatics, 2019 A shear flow device contained in the microscope incubator has newly been designed to study the effect of the shear stress field on the biological cell in vitro.
Shigehiro Hashimoto +2 more
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Self-curling 3D oriented scaffolds from fish scales for skeletal muscle regeneration
Biomaterials Research, 2022 Background Volumetric muscle loss (VML) due to various reasons may cause motor dysfunction and tissue engineering has been proposed for muscle regeneration.
Yong Shi +6 more
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H2O2-induced mitochondrial fragmentation in C2C12 myocytes [PDF]
Free Radical Biology and Medicine, 2010 In skeletal muscle and many other cell types, mitochondria exist as an elaborate and dynamic network in which "individual" mitochondria exist only transiently even under nonstimulated conditions. The balance of continuous mitochondrial fission and fusion defines the morphology of the mitochondrial reticulum.
Xiying, Fan +2 more
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Cellular Physiology and Biochemistry, 2017 Background/Aims: Sarcopenia is characterized by an age-related decline in skeletal muscle plus low muscle strength and/or physical performance. Despite the clinical significance of sarcopenia, the molecular pathways underlying sarcopenia remain elusive ...
Suifeng Liu +7 more
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PLoS ONE, 2021 The interactions between skeletal muscle and bone have been recently noted, and muscle-derived humoral factors related to bone metabolism play crucial roles in the muscle/bone relationships.
Yoshimasa Takafuji +5 more
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Interleukin-1 stimulates catabolism in C2C12 myotubes
American Journal of Physiology-Cell Physiology, 2009 Interleukin-1 (IL-1) is an inflammatory cytokine that has been linked to muscle catabolism, a process regulated by muscle-specific E3 proteins of the ubiquitin-proteasome pathway. To address cellular mechanism, we tested the hypothesis that IL-1 induces myofibrillar protein loss by acting directly on muscle to increase expression of two critical E3 ...
Wei, Li +4 more
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Effects of electrical stimulation in C2C12 muscle constructs [PDF]
Journal of Tissue Engineering and Regenerative Medicine, 2008 Electrical stimulation affects the deposition of extracellular matrices and cellular differentiation. Type I collagen is one of the most abundant extracellular matrix proteins; however, not much is known about the effects of electrical stimulation on collagen type I deposition in C2C12 cells.
Hyoungshin, Park +6 more
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A) Cell count of the pluripotent mesenchymal cell line (C2C12) treated with different growth factors
, 2011 Copyright information:Taken from "Proliferating and differentiating effects of three different growth factors on pluripotent mesenchymal cells and osteoblast like cells"http://www.josr-online.com/content/2/1/27Journal of Orthopaedic Surgery and Research ...
Gerhard Schmidmaier (86484) +4 more
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Pharmaceutics, 2020 In drug repositioning research, a new concept in drug discovery and new therapeutic opportunities have been identified for existing drugs. Midazolam (MDZ) is an anesthetic inducer used for general anesthesia.
Yukihiko Hidaka +8 more
doaj +1 more source