Results 41 to 50 of about 38,034 (262)

Changes in expression of serine biosynthesis and integrated stress response genes during myogenic differentiation of C2C12 cells

, 2019
Skeletal muscle is a highly metabolic and dynamic tissue that is formed through the complex and well-organised process of myogenesis. Although there is a good understanding about the role of the Muscle Regulatory Factors during myogenesis, little is ...
Brameld, John M., Li, Congcong, Loughna, Paul T., Daniel, Zoe C.T.R., Parr, Tim, Brearley, Madelaine C.   +5 more
core   +1 more source

IL-4 Signaling Promotes Myoblast Differentiation and Fusion by Enhancing the Expression of MyoD, Myogenin, and Myomerger

Cells, 2023
Myoblast fusion is essential for skeletal muscle development, growth, and regeneration. However, the molecular mechanisms underlying myoblast fusion and differentiation are not fully understood.
Mitsutoshi Kurosaka, Yung-Li Hung, Shuichi Machida, Kazuhisa Kohda   +3 more
doaj   +1 more source

Altered NFAT localization in MyoZ1 KO and Fbxl21 KO C2C12 cells.

, 2022
(A) qPCR of MyoZ1 mRNA in control and MyoZ1 KO C2C12 cells. Data are presented as mean ± SEM (n = 3), **p MyoZ1 KO C2C12 cells. (B) Representative MYOZ1 immunofluorescence staining image of successful MyoZ1 knockdown in C2C12 cells using CRISPR-Cas9 ...
Collin M. Douglas (14305221), Sun Young Kim (91779), Marvin Wirianto (10571934), Kaori Ono (4516759), Ji Ye Lim (14305218), Seung-Hee Yoo (9260306), Celia Tran (14305227), Karyn A. Esser (14305230), Chorong Han (10571931), Justin H. Ji (14305224), Zheng Chen (49483), Eunju Kim (342950)   +11 more
core   +1 more source

Construction of HEK293 and C2C12 cell models transfected by LMNA mutant and related intracellular sublocalization of lamin A/C [PDF]

Jichu yixue yu linchuang, 2020
Objective To construct an expression vector of fusion protein from wild type LMNA and mutant and the lentivirus vector of LMNA mutant, to study the expression and sublocalization of lamin A/C and the change of nucleus in HEK293 and C2C12 cells.
TAN Dan-dan, CHAI Jing-yan, LIU Jian-yun, NIE Hong-bing, XIONG Hui, WU Xiang-bin
doaj  

Characterization of an acute muscle contraction model using cultured C2C12 myotubes. [PDF]

PLoS ONE, 2012
A cultured C2C12 myotube contraction system was examined for application as a model for acute contraction-induced phenotypes of skeletal muscle. C2C12 myotubes seeded into 4-well rectangular plates were placed in a contraction system equipped with a ...
Yasuko Manabe, Shouta Miyatake, Mayumi Takagi, Mio Nakamura, Ai Okeda, Taemi Nakano, Michael F Hirshman, Laurie J Goodyear, Nobuharu L Fujii   +8 more
doaj   +1 more source

Ginsenoside compound K ameliorates palmitate-induced atrophy in C2C12 myotubes via promyogenic effects and AMPK/autophagy-mediated suppression of endoplasmic reticulum stress

Journal of Ginseng Research, 2022
Background: Compound K (CK) is among the protopanaxadiol (PPD)-type ginsenoside group, which produces multiple pharmacological effects. Herein, we examined the effects of CK on muscle atrophy under hyperlipidemic conditions along with its pro-myogenic ...
Tae Jin Kim, Do Hyeon Pyun, Myeong Jun Kim, Ji Hoon Jeong, A.M. Abd El-Aty, Tae Woo Jung   +5 more
doaj   +1 more source

Simple method for sub-diffraction resolution imaging of cellular structures on standard confocal microscopes by three-photon absorption of quantum dots

, 2013
This study describes a simple technique that improves a recently developed 3D sub-diffraction imaging method based on three-photon absorption of commercially available quantum dots.
Heidbreder, Meike, Mike Heilemann, Heilemann, M., Kaltschmidt Christian, Widera, D., Stefan Hauser, Darius Widera (30596), Christian Kaltschmidt, Cseresnyes, Z., Heidbreder Meike, Anje Sporbert, Stefan Hauser (356140), Sporbert Anje, Kaltschmidt, Christian, Kaltschmidt, B., Anje Sporbert (59307), Cseresnyes Zoltan, Heidbreder, M., Kaltschmidt, Barbara, Petra Domaing, Christian Kaltschmidt (30599), Zoltan Cseresnyes (110362), Darius Widera, Hauser Stefan, Kaltschmidt Barbara, Domaing, P., Mike Heilemann (5654950), Sporbert, A., Sporbert, Anje, Widera, Darius, Widera, Darius ; https://orcid.org/, Widera Darius, Barbara Kaltschmidt (30598), Petra Domaing (59308), Meike Heidbreder (414264), Hauser, Stefan, Meike Heidbreder, Barbara Kaltschmidt, Hauser, S., Kaltschmidt, C., Zoltan Cseresnyes, Cseresnyes, Zoltan, Heilemann, Mike, Domaing Petra, Heilemann Mike, Domaing, Petra   +45 more
core   +1 more source

SMRT suppresses β-oxidation during the differentiation of C2C12 cells.

, 2022
(A) The mRNA expressions of β-oxidation-related gene in both C2C12-WT and C2C12-SKO cells were quantified by qPCR (n = 3 per group). (B) Protein expressions of PPARδ, PGC-1α and AMPK2 were assessed by WB (n = 3 per group).
Hiroaki Shimizu (440570), Anthony N. Hollenberg (3628670), Yasuhiro Horibata (625218), Izuki Amano (5213840), Megan J. Ritter (14203815), Hiromi Ando (14203821), Mariko Domae (14203818), Ronald N. Cohen (7207826), Hiroyuki Sugimoto (625219)   +8 more
core   +1 more source

Effect of Rubus anatolicus Leaf Extract on Glucose Metabolism in HepG2, CRI-D2 and C2C12 Cell Lines

Diabetes, Metabolic Syndrome and Obesity, 2020
Mahdieh Safarzad,1 Abdoljalal Marjani,1 Marie Saghaeian Jazi,1 Durdi Qujeq,2 Seyed Mostafa Mir,2 Majid Marjani,3 Abbas Nezhadebrahimi Kaldehi1 1Metabolic Disorders Research Center, Department of Biochemistry and Biophysics, Gorgan Faculty of Medicine ...
Safarzad M, Marjani A, Saghaeian Jazi M, Qujeq D, Mir SM, Marjani M, Nezhadebrahimi Kaldehi A   +6 more
doaj  

PFN2a Suppresses C2C12 Myogenic Development by Inhibiting Proliferation and Promoting Apoptosis via the p53 Pathway

Cells, 2019
Skeletal muscle plays a crucial role in physical activity and in regulating body energy and protein balance. Myoblast proliferation, differentiation, and apoptosis are indispensable processes for myoblast myogenesis.
Huaqin Li, Lianjie Hou, Yu Zhang, Fangyi Jiang, Yifan Zhu, Qing X. Li, Ching Yuan Hu, Chong Wang   +7 more
doaj   +1 more source