Results 11 to 20 of about 38,034 (262)
Irisin promotes C2C12 myoblast proliferation via ERK-dependent CCL7 upregulation.
PLoS ONE, 2019 Irisin is an exercise-induced myokine that has various physiological functions, such as roles in energy expenditure, glucose/lipid metabolism, and muscle development.
Jangho Lee +4 more
doaj +2 more sources
Involvement of DPY19L3 in Myogenic Differentiation of C2C12 Myoblasts [PDF]
Molecules, 2021 DPY19L3 has been identified as a C-mannosyltransferase for thrombospondin type-1 repeat domain-containing proteins. In this study, we focused on the role of DPY19L3 in the myogenic differentiation of C2C12 mouse myoblast cells. We carried out DPY19L3 gene depletion using the CRISPR/Cas9 system.
Kento Mori +3 more
openaire +3 more sources
Journal of Biomechanical Science and Engineering, 2023 Atrophy is characterized by muscle weakness and reduced mobility and results from inactivity, aging, cancer cachexia, and excessive glucocorticoid use.
Kota KISHISHITA +8 more
doaj +1 more source
How Does a Cell Change Flow Direction Due to a Micro Groove? [PDF]
Journal of Systemics, Cybernetics and Informatics, 2021 The change in direction of a cell flowing over an oblique micro groove has been analyzed in vitro. The micro flow-channel (0.05 mm height × 1 mm width × 25 mm length) with oblique micro grooves (4.5 μm depth) was manufactured on a polydimethylsiloxane ...
Shigehiro Hashimoto +2 more
doaj
PLoS ONE, 2022 BackgroundSilencing Mediator of Retinoid and Thyroid hormone receptors (SMRT; NCoR2) is a transcriptional corepressor (CoR) which has been recognized as an important player in the regulation of hepatic lipogenesis and in somatic development in mouse ...
Hiroaki Shimizu +8 more
doaj +3 more sources
HSP70 drives myoblast fusion during C2C12 myogenic differentiation
Biology Open, 2020 In response to injury, skeletal muscle stem cells (MuSCs) undergo myogenesis where they become activated, proliferate rapidly, differentiate and undergo fusion to form multinucleated myotubes. Dramatic changes in cell size, shape, metabolism and motility
Savant S. Thakur +7 more
doaj +1 more source
Proteome Dynamics during C2C12 Myoblast Differentiation [PDF]
Molecular & Cellular Proteomics, 2005 Mouse-derived C2C12 myoblasts serve as an experimentally tractable model system for investigating the molecular basis of skeletal muscle cell specification and development. To examine the biochemical adaptations associated with myocyte formation comprehensively, we used large scale gel-free tandem mass spectrometry to monitor global proteome ...
Thomas, Kislinger +5 more
openaire +2 more sources
Movement of Cell Flowing Over Oblique Microgroove [PDF]
Journal of Systemics, Cybernetics and Informatics, 2023 The bumping movement of the cell flowing over an oblique microgroove was analyzed in vitro. The micro flow-channel (0.05 mm high, 1 mm wide, 25 mm long) with rectangular grooves (4.5 Μm deep, 0.2 mm long) was manufactured of polydimethylsiloxane (PDMS ...
Shigehiro Hashimoto +2 more
doaj
Simvastatin suppresses the differentiation of C2C12 myoblast cells via a Rac pathway. [PDF]
, 2008 Statins, which are known as cholesterol-lowering drugs, have several additional effects including the enhancement of bone formation and the stimulation of smooth muscle cell proliferation.
Baba, Tomomi T +3 more
core +1 more source
AdipoR-knockdown of C2C12 myotubes.
, 2022 (A) AdipoR-knockdown of C2C12 myotubes by AdipoR1-specific siRNA transfection. The total cell protein was extracted from treated C2C12 myotubes and analyzed by western blotting. Data are presented as mean ± SEM from independent experiments (n = 6 /group).
Shinsuke Mohri (4763235) +12 more
core +1 more source