Results 1 to 10 of about 28,568 (217)
Biology, 2021 Myocilin (MYOC) is a glycoprotein encoded by a gene associated with glaucoma pathology. In addition to the eyes, it also expresses at high transcription levels in the heart and skeletal muscle.
Huili Tong, Yunqin Yan
exaly +3 more sources
Cytoprotective Effect of Hispidin against Palmitate-Induced Lipotoxicity in C2C12 Myotubes
Molecules, 2015 It is well known that Phellinus linteus, which produces hispidin and its derivatives, possesses antioxidant activities. In this study, we investigated whether hispidin has protective effects on palmitate-induced oxidative stress in C2C12 skeletal muscle ...
Jong Lee, Suk-Jin Ha, Eock Kee Hong
exaly +3 more sources
Molecular Therapy - Nucleic Acids, 2020 Skeletal muscle is an important metabolic organ of the body, and impaired skeletal muscle differentiation can result in a wide range of metabolic diseases.
Yihao Liu, Haigang Cao, Kuilong Huang
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Anoctamin 6 regulates C2C12 myoblast proliferation. [PDF]
PLoS ONE, 2014 Anoctamin 6 (Ano6) belongs to a conserved gene family (TMEM16) predicted to code for eight transmembrane proteins with putative Ca2+-activated chloride channel (CaCC) activity.
Piming Zhao +6 more
doaj +4 more sources
Rutin and Gallic Acid Regulates Mitochondrial Functions via the SIRT1 Pathway in C2C12 Myotubes
Antioxidants, 2021 Mitochondria are highly dynamic organelles, balancing synthesis and degradation in response to increases in mitochondrial turnover (i.e., biogenesis, fusion, fission, and mitophagy) and function.
Wei-Tang Chang +2 more
exaly +3 more sources
Culture, Differentiation and Transfection of C2C12 Myoblasts
Bio-Protocol, 2012 C2C12 myoblasts are commonly used in biomedical laboratories as an in vitro system to study muscle development and differentiation. This protocol explains the basic procedures of culture, transfection and differentiation of C2C12 myoblast cells.
Lili Jing
doaj +2 more sources
Therapeutic effect of psoralen on muscle atrophy induced by tumor necrosis factor-α [PDF]
Iranian Journal of Basic Medical Sciences, 2020 Objective(s): To observe and determine the effect and mechanism of psoralen on tumor necrosis factor-α (TNF-α)-induced muscle atrophy.Materials and Methods: Three sets of C2C12 cells, including blank control, TNF-α (10 or 20 ng/ml) treatment and a TNF-α (
Xin-Feng Lin +7 more
doaj +1 more source
Kinetin stimulates differentiation of C2C12 myoblasts
PLOS ONE, 2021 Kinetin or N6-furfuryladenine (K) belongs to a class of plant hormones called cytokinins, which are biologically active molecules modulating many aspects of plant growth and development. However, biological activities of cytokinins are not only limited to plants; their effects on animals have been widely reported in the literature.
Michal Mielcarek, Mark Isalan
openaire +5 more sources
Mitochondrial Calcium Oscillations in C2C12 Myotubes [PDF]
Journal of Biological Chemistry, 2001 Mitochondrial Ca(2+) concentration ([Ca(2+)](m)) was monitored in C2C12 skeletal muscle cells stably expressing the Ca(2+)-sensitive photoprotein aequorin targeted to mitochondria. In myotubes, KCl-induced depolarization caused a peak of 3.03 +/- 0.14 micrometer [Ca(2+)](m) followed by an oscillatory second phase (5.1 +/- 0.1 per min).
Challet, C +3 more
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The nucleotide receptors on mouse C2C12 myotubes [PDF]
British Journal of Pharmacology, 1992 1. The response of C2C12 mouse myotubes to stimulation with adenosine triphosphate (ATP) and other nucleotides was studied by measuring changes in membrane potential. 2. A transient hyperpolarization followed by a slowly declining depolarization of the cells was observed in the presence of ATP (10 microM-1 mM). 3. The hyperpolarization was not observed
Henning, R.H. +3 more
openaire +2 more sources