Results 171 to 180 of about 6,779 (207)

Interaction of soluble C3 fragments with guinea pig lymphocytes. Comparison of effects of C3a, C3b, C3c, and C3d on lymphokine production and lymphocyte proliferation.

Journal of Immunology, 1976
C3a, C3b, C3c, and C3d were generated from purified guinea pig C3 by trypsin treatment. These fragments were characterized immunochemically and functionally by rosette inhibition.
W. Koopman, Ann L. Sandberg, S. Wahl, Stephan E. Mergenhagen   +3 more
semanticscholar   +1 more source

C3c-binding in inflammatory rheumatic diseases.

Clinical and experimental rheumatology, 1985
Sera from 73 patients, 24 with rheumatoid arthritis (RA), 10 with Sjögren's syndrome (SS, 4 with and six without RA), 17 with Reiter's syndrome (RS), 10 with systemic lupus erythematosus (SLE), 9 with Yersinia arthritis (YA), and 3 with mixed connective tissue disease (MCTD) were examined by enzyme-immunoassay (EIA) for the presence of C3c-binding IgG,
A, Hautanen, M, Gripenberg, E M, Salonen, I, Julkunen, O, Laitinen   +4 more
openaire   +1 more source

Epitope specificities and quantitative and serologic aspects of monoclonal complement (C3c and C3d) antibodies

Transfusion, 1987
Twenty‐two monoclonal antibodies to human C3c and ten to C3d were obtained by hybridization after the immunization of mice with complement‐coated human red cells and/or purified human complement components. C3c antibodies were variable in their agglutination reactions with cells coated with C3 by antibody in vitro; more consistent and potent reactions ...
D, Dobbie, D M, Brazier, B, Gardner, A M, Holburn   +3 more
openaire   +2 more sources

A simple method for preparation of C3c fragment from trypsinized serum‐ reacted zymosan

Transfusion, 1980
A simple method for preparing relatively pure C3c fragment from serum‐ reacted zymosan is described. Although hyperimmunization studies indicate contamination of the “C3c” product by C3d and immunoglobulin antigenic materials, these are present in such small amounts that they do not impair the effectiveness of the product as a reagent for absorbing ...
H, Chaplin, N L, Hoffmann, M C, Monroe
openaire   +2 more sources

IUD-induced changes in cervical secretion content of albumin, IgG and complement C3c

Contraception, 1984
Cervical secretion albumin, IgG, complement C3c, spinnbarkeit and amount of wet weight mucus recovered were analyzed in a group of 13 women using IUD as a contraceptive method and the results were compared to those obtained in a control group. Significant differences were obtained when concentrations and amounts of soluble proteins in the respective ...
L, Fleetwood, B M, Landgren, P, Eneroth
openaire   +2 more sources

C3C--Code for Cognizant Contracting: A Pathway to the Future of Online Contracting

SSRN Electronic Journal, 1999
Despite the global embrace of electronic commerce, there has been a surprising lack of attention to the host of new legal issues raised by online contracting. The attempts by the ALI and NCCUSL to clarify this uncertain legal landscape through the creation of a new uniform set of default rules for online transactions, first in the guise of U.C.C ...
openaire   +1 more source

Evidence for C3c Acceptor Sitesfor the Fixation of ComplementRelated Protein Fragments

Journal of Biology and Health Science
Fixation of complement-related protein fragments occurs following treatment of Raji, a CR2-positive lymphoblastoma cell line, with NHS but not with hi-S.From the immunoblot developed by autoradiography of cells pretreated with OKB7, an anti-CR2 moAbandsubsequently treated with I125NHS, two proteins of 60 and 74 kD were ...
openaire   +1 more source

Rapid turbidimetric determination of serum C3c and C4 by end point centrifugal analysis

Clinical Biochemistry, 1983
An end point turbidimetric method for the determination of C3c and C4 in serum using a centrifugal analyzer (Cobas Bio) is described. Several analytical factors were evaluated -pH, temperature, PEG and antibody concentration. Wide variations of temperature and pH did not significantly affect the turbidimetric reaction. A 20 g/L PEG concentration and 25-
L, Borque, E, Preciado, C, Zugaza, J, Eugui, R, Venta   +4 more
openaire   +2 more sources

Abstract 3736: C3C: A biomarker for extracellular cathepsin activity and ADCs

Cancer Research
Abstract Background: Antibody-drug conjugates (ADCs) combine the specificity of monoclonal antibodies with the potent cytotoxicity of small-molecules payloads. While classical ADCs rely on antigen binding, internalization and intracellular linker cleavage in the lysosomes recent studies show ...
Marina Crespo-Bravo, Nicholas Willumsen, Morten Karsdal   +2 more
openaire   +1 more source

C3c and C3d fragments of human C3 bind myeloma IgG1 and IgG3 proteins

Immunology Letters, 1982
Eight human myeloma proteins, two of each IgG subclass, were studied for binding to solid-phase C3c and C3d by the ELISA technique. Myeloma IgG1 kappa, IgG1 lambda, IgG3 kappa and IgG3 lambda proteins bound to C3c and C3d, while two IgG2 kappa, and two IgG4 kappa proteins failed to show significant binding affinity.
A, Hautanen, A, Sarnesto, J, Keski-Oja, I, Seppälä   +3 more
openaire   +2 more sources