Results 191 to 200 of about 4,947 (220)

IUD-induced changes in cervical secretion content of albumin, IgG and complement C3c

Contraception, 1984
Cervical secretion albumin, IgG, complement C3c, spinnbarkeit and amount of wet weight mucus recovered were analyzed in a group of 13 women using IUD as a contraceptive method and the results were compared to those obtained in a control group. Significant differences were obtained when concentrations and amounts of soluble proteins in the respective ...
L, Fleetwood, B M, Landgren, P, Eneroth
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Structure of C3c in complex with compstatin reveals a new mechanism of complement inhibition

Molecular Immunology, 2007
Bert Janssen - Conformational Complexity of Complement Component C3 60 Undesired complement activation is a major cause of tissue injury in various pathological conditions and contributes to several immune complex diseases. Compstatin, a 13-residue peptide, is an effective inhibitor of C3 activation thus preventing a central and crucial step in ...
Bert J.C. Janssen, Els Halff, John D. Lambris, Piet Gros   +3 more
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Rapid turbidimetric determination of serum C3c and C4 by end point centrifugal analysis

Clinical Biochemistry, 1983
An end point turbidimetric method for the determination of C3c and C4 in serum using a centrifugal analyzer (Cobas Bio) is described. Several analytical factors were evaluated -pH, temperature, PEG and antibody concentration. Wide variations of temperature and pH did not significantly affect the turbidimetric reaction. A 20 g/L PEG concentration and 25-
L, Borque, E, Preciado, C, Zugaza, J, Eugui, R, Venta   +4 more
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C3c and C3d fragments of human C3 bind myeloma IgG1 and IgG3 proteins

Immunology Letters, 1982
Eight human myeloma proteins, two of each IgG subclass, were studied for binding to solid-phase C3c and C3d by the ELISA technique. Myeloma IgG1 kappa, IgG1 lambda, IgG3 kappa and IgG3 lambda proteins bound to C3c and C3d, while two IgG2 kappa, and two IgG4 kappa proteins failed to show significant binding affinity.
A, Hautanen, A, Sarnesto, J, Keski-Oja, I, Seppälä   +3 more
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Abstract 3736: C3C: A biomarker for extracellular cathepsin activity and ADCs

Cancer Research
Abstract Background: Antibody-drug conjugates (ADCs) combine the specificity of monoclonal antibodies with the potent cytotoxicity of small-molecules payloads. While classical ADCs rely on antigen binding, internalization and intracellular linker cleavage in the lysosomes recent studies show ...
Marina Crespo-Bravo, Nicholas Willumsen, Morten Karsdal   +2 more
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Complement C3c and C3d in plasma and synovial fluid in rheumatoid arthritis.

Acta pathologica, microbiologica, et immunologica Scandinavica. Section C, Immunology, 1984
By means of recently developed immunochemical assays increased levels of the complement C3c and C3d split products were found in synovial fluids of patients with rheumatoid arthritis (RA) as compared with synovial fluids of patients with traumatic synovitis (TS). In plasma, only the C3d levels were significantly increased compared with plasma levels of
A, Berkowicz, E, Kappelgaard, J, Petersen, H, Nielsen, T, Ingemann-Hansen, J, Halkjaer-Kristensen, H, Sørensen   +6 more
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Release of C3c from bound C3bi by C3b inactivator

Molecular Immunology, 1982
R.G. Medicus, M.A. Arnaout
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Partial characterization of physiologically generated C3 components expressing C3d but not C3c epitopes.

Journal of clinical & laboratory immunology, 1983
Techniques for the quantification of C3d are shown to estimate the sum of 4 different plasma protein components possessing C3d but not C3c epitopes. All 4 components were C3-derived polypeptides as shown by activating serum containing 125I-labelled C3, isolating the anti-C3d reactive material in 14% PEG supernatant, followed by analysis on SDS-PAGE and
Siersted, Hans Christian, Jensenius, Jens Christian, Svehag, S E, Brandslund, Ivan   +3 more
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Crystal structure of CRIg in complex with C3c

Molecular Immunology, 2007
Christian Wiesmann, Micah Steffek, Jian Ping Yin, Karim Helmy, Kenneth Katschke, Phil Hass, Menno van Lookeren Campagne   +6 more
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[Evaluation of C3c, C4 and C1-esterase inhibitor (C1-INH) during unstable angina].

Minerva cardioangiologica, 2002
The complement system plays an important role in the physiopathology of acute myocardial infarction (AMI) taking part in myocardial damage and reperfusion injury. The aim of this study is to investigate the plasmatic levels of some complement components (C3c, C4 and C1-INH) during unstable angina (C1-INH) and their different concentrations in relation ...
DANESE, Chiara Rita, MARCIANO F, CIARLA MV, CURIONE, Mario, ANGRISANI L, FERRANTI E, BORGIA, Maria Clotilde   +6 more
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