Results 181 to 190 of about 6,779 (207)
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Structure of C3c in complex with compstatin reveals a new mechanism of complement inhibition
Molecular Immunology, 2007Bert Janssen - Conformational Complexity of Complement Component C3 60 Undesired complement activation is a major cause of tissue injury in various pathological conditions and contributes to several immune complex diseases. Compstatin, a 13-residue peptide, is an effective inhibitor of C3 activation thus preventing a central and crucial step in ...
Bert J.C. Janssen +3 more
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Complement C3c and C3d in plasma and synovial fluid in rheumatoid arthritis.
Acta pathologica, microbiologica, et immunologica Scandinavica. Section C, Immunology, 1984By means of recently developed immunochemical assays increased levels of the complement C3c and C3d split products were found in synovial fluids of patients with rheumatoid arthritis (RA) as compared with synovial fluids of patients with traumatic synovitis (TS). In plasma, only the C3d levels were significantly increased compared with plasma levels of
A, Berkowicz +6 more
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Immunology, 1994
Bovine conglutinin is a serum lectin that agglutinates erythrocytes preincubated with antibodies and complement. This agglutination occurs through the binding of conglutinin to iC3b, a fragment of the complement component C3. It was reported that conglutinin binds fluid-phase C3b and C3c as well as iC3b. We re-investigated the reactivity of conglutinin
Laursen, S B +6 more
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Bovine conglutinin is a serum lectin that agglutinates erythrocytes preincubated with antibodies and complement. This agglutination occurs through the binding of conglutinin to iC3b, a fragment of the complement component C3. It was reported that conglutinin binds fluid-phase C3b and C3c as well as iC3b. We re-investigated the reactivity of conglutinin
Laursen, S B +6 more
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Journal of clinical & laboratory immunology, 1983
Techniques for the quantification of C3d are shown to estimate the sum of 4 different plasma protein components possessing C3d but not C3c epitopes. All 4 components were C3-derived polypeptides as shown by activating serum containing 125I-labelled C3, isolating the anti-C3d reactive material in 14% PEG supernatant, followed by analysis on SDS-PAGE and
Siersted, Hans Christian +3 more
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Techniques for the quantification of C3d are shown to estimate the sum of 4 different plasma protein components possessing C3d but not C3c epitopes. All 4 components were C3-derived polypeptides as shown by activating serum containing 125I-labelled C3, isolating the anti-C3d reactive material in 14% PEG supernatant, followed by analysis on SDS-PAGE and
Siersted, Hans Christian +3 more
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Crystal structure of CRIg in complex with C3c
Molecular Immunology, 2007Christian Wiesmann +6 more
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Release of C3c from bound C3bi by C3b inactivator
Molecular Immunology, 1982R.G. Medicus, M.A. Arnaout
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[Evaluation of C3c, C4 and C1-esterase inhibitor (C1-INH) during unstable angina].
Minerva cardioangiologica, 2002The complement system plays an important role in the physiopathology of acute myocardial infarction (AMI) taking part in myocardial damage and reperfusion injury. The aim of this study is to investigate the plasmatic levels of some complement components (C3c, C4 and C1-INH) during unstable angina (C1-INH) and their different concentrations in relation ...
DANESE, Chiara Rita +6 more
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