Results 31 to 40 of about 6,868 (161)

The diagnostic value of immunohistochemical staining of the interstitial vascular C4d complement in membranous nephropathy

open access: yesCurrent Issues in Pharmacy and Medical Sciences, 2021
Membranous glomerulonephritis (MGN) is the most common cause of adulthood nephrotic syndrome. Diagnosis of membranous nephritis is based on light electron immunofluorescence microscopy and clinical signs.
Pourlak Tala   +4 more
doaj   +1 more source

C4d Deposition in Acute Rejection [PDF]

open access: yesJournal of the American Society of Nephrology, 2002
Peritubular capillary deposition of C4d has been demonstrated to be associated with both acute humoral and vascular rejection and increased graft loss. Whether it is an independent predictor of long-term graft survival rates is uncertain. The biopsies (n = 126) from all patients (n = 93) with a tissue diagnosis of acute rejection that were performed ...
Andrew M, Herzenberg   +3 more
openaire   +2 more sources

Noninvasive and quantitative measurement of C4d deposition for the diagnosis of antibody-mediated cardiac allograft rejectionResearch in context

open access: yesEBioMedicine, 2018
Background: C4d is a specific biomarker for the diagnosis of antibody-mediated rejection (AMR) after cardiac transplantation. Although strongly recommended, routine C4d surveillance is hindered by the invasive nature of endomyocardial biopsy.
Tao Liao   +9 more
doaj   +1 more source

Study of the variables associated with local complement activation in IgA nephropathy

open access: yesNefrología (English Edition), 2017
Objectives: 1. To identify the variables that are associated with urinary levels of properdin, MBL, C4d, and C5b-9 in patients with idiopathic IgA nephropathy. 2. To analyse whether urinary levels of MBL and/or C4d are useful for identifying the presence
Alfons Segarra-Medrano   +6 more
doaj   +1 more source

The Intensity of PLA2R and C4d Immunoexpression in Primary Membranous Nephropathy

open access: yesSouthern Clinics of Istanbul Eurasia, 2020
INTRODUCTION[|]Antibodies against the phospholipase A2 receptor (PLA2R) on podocyte membranes result in the formation of immune complexes that cause loss of function of the glomerular basement membrane in primary membranous nephropathy (PMN). It has also
Deniz Filinte   +5 more
doaj   +1 more source

Glomerular C4d Deposition and Kidney Disease Progression in IgA Nephropathy: A Systematic Review and Meta-analysisPlain-Language Summary

open access: yesKidney Medicine, 2021
Background: Glomerular deposition of C4d is a widely used biomarker for activation of the lectin pathway in the complement system and is reported to be associated with kidney progression in immunoglobulin A nephropathy (IgAN).
Yuanyuan Jiang   +8 more
doaj   +1 more source

Glomerular C4d Staining Does Not Exclude a C3 Glomerulopathy

open access: yesKidney International Reports, 2019
Introduction: C4d, an early product in the classical/lectin complement pathway has shown potential in the evaluation of C3 glomerulopathy where its absence would support an alternative pathway abnormality.
Geetika Singh   +11 more
doaj   +1 more source

Serum S100P and C4d proteins as markers for active proliferative lupus nephritis in Egyptian patients with systemic lupus erythematosus

open access: yesУкраїнський Журнал Нефрології та Діалізу, 2023
Lupus nephritis (LN), occurring in approximately 50% of individuals with systemic lupus erythematosus (SLE), significantly influences therapy and prognosis.
Mahmoud M. Elnokeety   +2 more
doaj   +1 more source

Generation cycles in experimental populations of a multivoltine insect

open access: yesJournal of Animal Ecology, EarlyView.
Although theory suggests various mechanisms by which environmental and ecological factors may drive generational fluctuations, our field‐cage experiment is the first to demonstrate how internal dynamics and external disturbances jointly produce synchronised, large‐scale outbreak cycles.
Takehiko Yamanaka   +3 more
wiley   +1 more source

Expresión de C4d en glomeruloesclerosis focal y segmentaria

open access: yesNefrología
Resumen: Antecedentes: Existe poca información acerca de la expresión del C4d (fragmento del complemento) en la glomeruloesclerosis focal y segmentaria (GEFS) y sus variantes.
Venice Chávez Valencia   +8 more
doaj   +1 more source

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