Results 111 to 120 of about 24,312 (217)

Plasma Extracellular Vesicles‐Derived Complement Proteins as Biomarkers of Sarcopenia Progression in Longitudinal Cohorts

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 4, August 2026.
ABSTRACT Background Sarcopenia is characterized by progressive loss of muscle mass, strength and physical performance, yet current diagnostic tools are limited for practical and longitudinal monitoring. Extracellular vesicles (EVs) encapsulate various biomolecules, including proteins, nucleic acids, lipids and metabolites and have emerged as promising ...
Ji Yeon Kim   +11 more
wiley   +1 more source

C5A [PDF]

open access: yesScience-Business eXchange, 2008
openaire   +1 more source

Immunoinflammatory Mechanisms and Biocompatibility of Bioactive Dental Biomaterials: From Fundamental Insights to Clinical Translation

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 27, 17 July 2026.
Surface‐host dialogue at the implant interface governs biological fate and osseointegration. Surface physicochemical properties of titanium (Ti) dental implants, including microgrooves, nanopatterns, nanotopography, roughness, and wettability, modulate the initial adsorption of proteins and the formation of a dynamic biointerface.
Daniela Moreira Cunha   +9 more
wiley   +1 more source

Fourier Expansion‐Based Approach to the Parameter Space of Classical Systems

open access: yesAnnalen der Physik, Volume 538, Issue 7, July 2026.
ABSTRACT We propose a new approach to compute the classical metric tensor (CMT) and the Hannay curvature using Fourier series expansions in action‐angle variables. This approach circumvents the need for complex time‐domain integrals or the construction of generating functions, replacing them with algebraic combinations of Fourier coefficients. We prove
Marcos J. Hernández   +3 more
wiley   +1 more source

From Inflammatory Bowel Disease to Cancer: Gut Microbiota–Immune Microenvironment Crosstalk and Natural Product‐Based Therapeutic Opportunities

open access: yesCancer Nexus, Volume 2, Issue 3, July 2026.
ABSTRACT Inflammatory bowel disease (IBD), primarily Crohn's disease and ulcerative colitis, is a chronic relapsing inflammatory disorder of the gastrointestinal tract and an important risk factor for IBD‐associated cancer. Increasing evidence suggests that gut microbiota dysbiosis, epithelial barrier dysfunction, and immune microenvironment remodeling
Xue Zhang   +4 more
wiley   +1 more source

Projecting future damage costs of non‐native species using combined dynamical and cost–density equations

open access: yesEcological Applications, Volume 36, Issue 5, July 2026.
Abstract Biological invasions threaten biodiversity, economic stability, and public health, exacerbated by intensive global trade and transport. The economic costs of these invasions have exceeded US$2 trillion globally and continue to increase. Although past invasion costs have been described across various contexts, there are few robust projections ...
Danish A. Ahmed   +11 more
wiley   +1 more source

Complement Inhibition in the Clinic: Are We Doing Enough to Protect Patients From Infection?

open access: yesEuropean Journal of Immunology, Volume 56, Issue 7, July 2026.
Excessive complement activation is implicated in a broad range of diseases. Therapeutic approaches targeting the complement cascade, from pathway‐selective inhibition to terminal blockade, can effectively control disease activity. However, increasing degrees of complement inhibition are associated with a heightened susceptibility to bacterial, viral ...
Serena Bettoni   +4 more
wiley   +1 more source

Reduced Complement and Granulocyte Activation by α‐Gal Knockout Porcine Pericardium for Bioprosthetic Heart Valves: A Pilot Hemocompatibility Study

open access: yesJournal of Biomedical Materials Research Part A, Volume 114, Issue 7, July 2026.
Genetically modified, α‐Gal‐depleted porcine pericardium and wild type tissues are investigated for hemocompatibility and material properties such as mechanobiology and ECM profile to carve out the suitability of the gene‐modified tissue as material for biological heart valve prostheses. ABSTRACT Xenogeneic pericardium is the main source for biological
Claudia Dittfeld   +7 more
wiley   +1 more source

Ischemia–Reperfusion Injury: Molecular Mechanisms and Therapeutic Interventions

open access: yesMedComm, Volume 7, Issue 7, July 2026.
Multiorgan ischemia–reperfusion injury begins with ischemia‐induced ATP depletion and ionic imbalance, followed by reperfusion‐triggered mitochondrial ROS/RNS bursts, regulated cell death, and DAMP release. Sterile inflammation converges on endothelial–immune–coagulation crosstalk, where NETs drive immunothrombosis, no‐reflow, and remote organ injury ...
Peng An   +4 more
wiley   +1 more source

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