Results 141 to 150 of about 30,655 (265)

Case Report: Aquaporin‐4–Positive Neuromyelitis Optica Spectrum Disorder: Diagnostic Challenges and Transition From B‐Cell Depletion Therapy to Ravulizumab

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT This case report illustrates the real‐world efficacy of complement component 5 inhibitors in a patient with neuromyelitis optica spectrum disorder who switched from rituximab because of B‐cell repopulation occurring early in the course of treatment.
Aram Zabeti
wiley   +1 more source

Cracking the cytokine code in sickle cell disease: Immune‐informatics for precision inflammation mapping, risk prediction and therapeutic discovery

Clinical and Translational Discovery, Volume 6, Issue 5, October 2026.
Sickle cell disease inflammation emerges from interconnected cytokine networks. Immune‐informatics integrates multi‐omics, network biology and artificial intelligence to decode inflammatory signatures, predict complications and identify precision therapeutic targets. Abstract Background Sickle cell disease (SCD) is characterised by chronic inflammation
Emmanuel Ifeanyi Obeagu, Chukwuma J. Okafor   +1 more
wiley   +1 more source

C1qc Mediates Blood–Brain Barrier Disruption in a Mouse Model of Intracerebral Haemorrhage Through Microglia‐Derived Migrasomes

Journal of Extracellular Vesicles, Volume 15, Issue 10, October 2026.
Microglia‐derived migrasomes induce vascular endothelial pyroptosis through C1qc delivery, uncovering a novel mechanism of blood–brain barrier (BBB) disruption after intracerebral haemorrhage (ICH) and proposing a novel therapeutic strategy targeting extracellular vesicles (EVs).
Mengyuan Li, Zhihua Li, Dengpan Song, Fang Wang, Mengzhao Feng, Chi‐Tai Yeh, Tingting Zhai, Menghan Deng, Yanyan Sun, Junyang Wang, Xuemei Chen, Yating Wang, Qiong Yang, Moxin Wu, Xiaoping Yin, Junmin Wang, Jian Wang, Fuyou Guo   +17 more
wiley   +1 more source

Complement 5 (C5); C5a; C5a receptor [PDF]

Science-Business eXchange, 2008
openaire   +1 more source

Neutrophil Extracellular Traps in Atherosclerosis and Cardiovascular Disease

MedComm, Volume 7, Issue 10, October 2026.
NETs as integrated effectors in the atherosclerotic cardiovascular disease continuum. Activated neutrophils release NETs that promote endothelial injury, thrombo‐inflammation, and plaque destabilization throughout atherosclerotic disease progression. Created with BioRender.com.
Ji Zhang, Fangjiaqi Wei, Mengdi Qu, Yuwen Shao, Tingye Xu, Darko Stojkov, Hans‐Uwe Simon, Ben Huang, Changhong Miao, Hao Zhang   +9 more
wiley   +1 more source

Liver Metastases from Colorectal Cancer: From Pathogenesis to Current Treatment

MedComm, Volume 7, Issue 10, October 2026.
The liver is not merely a passive recipient of disseminated tumor cells, but a unique metastatic organ shaped by anatomical, metabolic, and immunological characteristics that support tumor colonization. Increasing evidence indicates that colorectal cancer liver metastasis development is driven by dynamic interactions between tumor intrinsic programs ...
Jialiang Fan, Huiru Zhang, Deyang Kong, Yu Sun, Shuaibing Lu, Wenjing Yang, Renshen Xiang, Qi Zhang, Wei Pei, Haizeng Zhang, Lin Feng   +10 more
wiley   +1 more source

Intratumoral Microbiota in Fueling Cancer and Steering Treatment Response

MedComm, Volume 7, Issue 10, October 2026.
Emerging research underscores the tumor‐specific colonization of microbiota and the role of intratumoral microbiota in cancer development and treatment resistance across multiple malignancies. Here, we provide a systematic review exploring the latest biotechnological advancements for studying low‐abundance intratumoral microbiota, their origins ...
Minhui Xu, Jie Yu, Ying Chen, Shengfang Ge, Lin Ye, Yefei Wang, Yixiong Zhou, Renbing Jia   +7 more
wiley   +1 more source

Unique Associations Between Complement Split Products and Pollen Species in Adults with Respiratory Allergic Disease: A Pilot Study. [PDF]

J Asthma Allergy
Nagarajan S, Smith-Norowitz T, Bluth MH, Eng A, Pak Y, Kohlhoff S, Joks R.   +6 more
europepmc   +1 more source

Seismic evaluation of the southbound Stellenberg Interchange Bridge, B5593, in South Africa

Structural Concrete, Volume 27, Issue 5, Page 8435-8452, October 2026.
Abstract This study presents a nonlinear finite element assessment of the seismic vulnerability of Bridge B5593, located in the south‐western region of South Africa. Previous evaluations identified a high likelihood of column failure; however, these were based on linear material models incapable of capturing damage evolution.
Wandie Olivier, Trevor Haas
wiley   +1 more source

Complement tumor-crosstalk: the role of C5a receptors in urothelial carcinomas. [PDF]

Front Immunol
Lütje LS, Gruner C, Karsten CM, Merseburger AS, Roesch MC.   +4 more
europepmc   +1 more source