Safety, tolerability, pharmacokinetics, pharmacodynamics, and immunogenicity of STSA-1002, recombinant anti-human C5a fully human monoclonal antibody, in a randomized, first-in-human phase I study in healthy adults. [PDF]
Front PharmacolFang Y +16 more
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Complement C5a Promotes Epithelial-Mesenchymal Transition in Pterygium via C5aR Activation. [PDF]
Invest Ophthalmol Vis SciHan J +6 more
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The Comprehensive Live Cell-Based Cytotoxicity Assay for Monitoring Disease Activity and Guiding Rescue Therapy in Acute Attacks of NMOSD. [PDF]
Ann Clin Transl NeurolXu X +10 more
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From ANCA-mediated vascular injury to coronary microvascular and myocardial involvement in granulomatosis with polyangiitis: an immunocardiology perspective. [PDF]
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Intratumoral C3ar/C5ar1 Antagonists Imbedded in an In Situ Forming Implant Can Robustly Suppress Solid Tumors. [PDF]
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Profiling complement proteins in pediatric tuberculosis children with or without serological evidence of prior SARS-CoV-2 exposure. [PDF]
Front ImmunolKumar NP +14 more
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Complement-Targeted Therapies in Glioblastoma: A Systematic Review. [PDF]
BiomedicinesWalton CM, Strickland BA.
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Mathematical Modeling of the Complement System: a Scoping Review. [PDF]
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Heterogeneity of Immunological, Coagulation and Complement Clustering to Viral Challenge and Clinical Relevance. [PDF]
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