Results 131 to 140 of about 1,253,157 (246)

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

Journal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed, Sara El Moshy, Israa Ahmed Radwan, Dina Rady, Aiah A. El‐Rashidy, Marwa M. S. Abbass, Christof E. Dörfer   +6 more
wiley   +1 more source

Inhibition of C5a-induced neutrophil chemotaxis and macrophage cytokine production In vitro by a new C5a receptor antagonist

, 2000
A cyclic peptide, Phe-[Orn-Pro-D-Cyclohexylalanine-Trp-Arg] (F-[OPdChaWR]), was recently shown in vitro to antagonise the binding of C5a to its receptor (CD88) on human polymorphonuclear leukocytes (PMNs) and in vivo to inhibit the neutropenia associated
Fairlie, DP, Stephen M Taylor, Bignold, LP, David R Haynes, Fairlie, D., Hutchens, MJ, Harkin, DG, Taylor, S., Haynes, DR, Taylor, SM, Haynes, D., Harkin, D., Leon P Bignold, Bignold, L., Hutchens, M., Damien G Harkin, Martin J Hutchens, David P Fairlie   +17 more
core   +1 more source

The role of complement C5a receptor in DPSC odontoblastic differentiation and in vivo reparative dentin formation. [PDF]

Int J Oral Sci, 2022
Irfan M, Kim JH, Marzban H, Reed DA, George A, Cooper LF, Chung S.   +6 more
europepmc   +1 more source

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

Semiquantitative immunohistochemical analysis demonstrates C5a and C5a receptor (CD88) are increased in mice exposed to nPM.

, 2016
Left: Filtered air and nPM exposed mice euthanized at 24 hours and stained for C5a (red) in the ischemic region. Nuclei (DAPI) are stained in blue (A).
Qinghai Liu (503520), Caleb E. Finch (180776), William J. Mack (275824), Arati Patel (325472), Robin Babadjouni (2607898), Constantinos Sioutas (12169), Peter Baumbacher (2607901), Shuhan He (275821), Jonathan J. Russin (2607907), Todd E. Morgan (180755), Ryan Radwanski (2607895), Hank Cheng (2607892), Drew M. Hodis (2607904)   +12 more
core   +1 more source

Pharmacological activation of the C5a receptor leads to stimulation of the β-adrenergic receptor and alleviates cognitive impairment in a murine model of familial Alzheimer's disease. [PDF]

Front Immunol, 2022
Fella E, Papacharalambous R, Kynigopoulos D, Ioannou M, Derua R, Christodoulou C, Stylianou M, Karaiskos C, Kagiava A, Petroula G, Pierides C, Kyriakou M, Koumas L, Costeas P, Panayiotou E.   +14 more
europepmc   +1 more source

The Keystone‐Pathogen Hypothesis Updated: The Role of Porphyromonas gingivalis in Periodontitis

Journal of Periodontal Research, EarlyView.
Porphyromonas gingivalis orchestrates a coordinated manipulation of immune and inflammatory responses in periodontal tissues which leads to the generation of a dysbiotic, subgingival biofilm community, and progression of periodontitis. The type 9 secretion system, lipid A modification, and the formation of outer membrane vesicles are important ...
Mike A. Curtis, James A. Garnett, Richard P. Darveau   +2 more
wiley   +1 more source

C5L2: a controversial receptor of complement anaphylatoxin, C5a

, 2013
C5a is the paramount proinflammatory mediator of the complement cascade, and has been previously thought to act only through a single, G-protein- coupled, C5a receptor (C5aR; also termed CD88).
Coulthard, Liam G., Wu, M. C. L., Li, Rui, Woodruff, Trent M., Taylor, Stephen M.   +4 more
core   +1 more source

Aseptic meningitis due to intravenous immunoglobulin therapy (IVIG) in therapy‐refractory pyoderma gangraenosum

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Katharina A. Kälber, Knut Schäkel, Alexander Enk, Julia K. Winkler   +3 more
wiley   +1 more source

The Oral‐Gut Axis: Bidirectional Interactions Between Microbiome and Diseases

Journal of Periodontal Research, EarlyView.
This study aims to summarize the mechanisms underlying ectopic colonization of the gut by oral pathobionts and the microbial and host factors that regulate this process. ABSTRACT Increased colonization of typically oral microorganisms is frequently observed in the gut mucosa or lumen of individuals with gastrointestinal disorders, including patients ...
Shinya Ebihara, Nobuhiko Kamada
wiley   +1 more source