Results 151 to 160 of about 1,253,157 (246)
The role of the C5a receptor in a mouse model of Legionnaires\' disease
, 2016 Legionella longbeachae é uma espécie da família Legionellaceae que é comumente presente no solo em diversas regiões do globo. Uma infecção por L.
Stifanic, Renata
core +1 more source
Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.A recombinant AAV delivered tumour gene therapy. NF‐κB drives tumour‐selective antigen (e.g., CD20) expression. Ectopic CD20 enables rituximab repurposing to solid tumours. ADCC, ADCP, and CDC contribute to the antitumour activity. Abstract Background Despite the clinical success of cancer immunotherapies, their efficacy is often compromised by antigen‐
Ziyan Kong +6 more
wiley +1 more source
Author Correction: Submolecular probing of the complement C5a receptor-ligand binding reveals a cooperative two-site binding mechanism. [PDF]
Commun Biol, 2021 Dumitru AC +6 more
europepmc +1 more source
Glia, Volume 74, Issue 9, September 2026.Young adult deletion of microglial C1q reduced engulfment of Vglut1+ synapses and mitigated spatial cognitive deficits at 10 months of age in the amyloidopathy Arctic mouse model of AD. Neither fibrillar amyloid plaques nor soluble or insoluble Aβ levels in the hippocampus were affected by young adult microglial loss of C1q despite reduced phagocytosis
Tiffany J. Petrisko +4 more
wiley +1 more source
Vascular Endothelial Cells Produce Coagulation Factors That Control Their Growth via Joint Protease-Activated Receptor and C5a Receptor 1 (CD88) Signaling. [PDF]
Am J Pathol, 2022 Cao D +8 more
europepmc +1 more source
Health Science Reports, Volume 9, Issue 9, September 2026.ABSTRACT Background and Aims Long COVID, also known as post‐acute sequelae of SARS‐CoV‐2 infection (PASC), is a multisystem condition characterized by persistent symptoms that continue beyond the acute phase of infection. Growing evidence indicates that sustained immune dysregulation involving cytokine‐mediated inflammation, complement activation ...
Emmanuel Ifeanyi Obeagu
wiley +1 more source
Targeting m6A Modifications Regulating Ferroptosis Offers Novel Therapy in Diseases
Cell Proliferation, Volume 59, Issue 9, September 2026.m6A RNA modification regulates ferroptosis by balancing iron metabolism, lipid peroxidation, and antioxidant defenses. Dysregulated m6A signaling disrupts pro‐ and anti‐ferroptotic factors, leading to excess ROS, Fe3+ accumulation, and lipid peroxidation–driven cell death. Targeting m6A‐mediated ferroptotic regulation represents a promising therapeutic
Lida Du +7 more
wiley +1 more source
Xenotransplantation, Volume 33, Issue 5, September/October 2026.ABSTRACT Xenotransplantation represents a potential solution to the persistent global organ shortage, yet its clinical application remains stalled by complex immunologic responses, coagulation dysregulation, species‐specific biology, and infectious risks.
Kasra Shirini +7 more
wiley +1 more source
Immunohistochemical identification of complement peptide C5a receptor 1 (C5aR1) in non-neoplastic and neoplastic human tissues. [PDF]
PLoS One, 2021 Nürge B +6 more
europepmc +1 more source