Results 171 to 180 of about 1,253,157 (246)

Long-term use and remission of granulomatosis with polyangiitis with the oral C5a receptor inhibitor avacopan. [PDF]

BMJ Case Rep, 2020
Ennis D, Yeung RS, Pagnoux C.
europepmc   +1 more source

Complement 5 (C5); C5a; C5a receptor [PDF]

Science-Business eXchange, 2008
openaire   +1 more source

Cardiac Repair after Myocardial Infarction is Controlled by a Complement C5a Receptor 1-Driven Signaling Cascade. [PDF]

Thromb Haemost
Asare Y, Simsekyilmaz S, Köhncke J, Shagdarsuren G, Staudt M, Noels H, Klos A, Fischer JC, Bernhagen J, Zernecke A, Liehn EA, Shagdarsuren E.   +11 more
europepmc   +1 more source

Complement C5a Receptor Signaling in Macrophages Enhances Trained Immunity Through mTOR Pathway Activation. [PDF]

Immune Netw
Shim EH, Kim SH, Kim DJ, Jang YS.
europepmc   +1 more source

A novel hollow iron nanoparticle system loading PEG-Fe₃O₄ with C5a receptor antagonist for breast cancer treatment. [PDF]

Front Immunol
Yang H, Li G, Zhang J, Zhao J, Zhao Y, Wu Y, Sun Z, Song S, Zou Y, Zou Z, Han X, Deng B, Wang L, Rao H, Xu G, Wang S, Guo S, Ding H, Shi Y, Wu Y, Chen J.   +20 more
europepmc   +1 more source

A Newly Identified Protective Role of C5a Receptor 1 in Kidney Tubules against Toxin-Induced Acute Kidney Injury. [PDF]

Am J Pathol
Yu SM, King E, Fribourg M, Hartzell S, Tsou L, Gee L, D'Agati VD, Thurman JM, He JC, Cravedi P.   +9 more
europepmc   +1 more source

Preclinical Pharmacokinetics of Complement C5a Receptor Antagonists PMX53 and PMX205 in Mice. [PDF]

ACS Omega, 2020
Kumar V, Lee JD, Clark RJ, Noakes PG, Taylor SM, Woodruff TM.   +5 more
europepmc   +1 more source

Complement C5a receptor inhibition reduces atherosclerosis in ApoE-/- mice.

, 2011
The complement C5a receptor, CD88, is present on many of the cells found within human atherosclerotic plaques, but little is known about the role of C5a in atherogenesis.
Shiels, Ian, Thomas, Anita C, Taylor, Stephen, Manthey, Helga, Zerneke, Alma, Rolfe, Barbara, Woodruff, Trent   +6 more
core  

Knockout mouse models reveal the contributions of G protein subunits to complement C5a receptor-mediated chemotaxis. [PDF]

J Biol Chem, 2020
van den Bos E, Ambrosy B, Horsthemke M, Walbaum S, Bachg AC, Wettschureck N, Innamorati G, Wilkie TM, Hanley PJ.   +8 more
europepmc   +1 more source

Adjunctive Treatment With Avacopan, an Oral C5a Receptor Inhibitor, in Patients With Antineutrophil Cytoplasmic Antibody-Associated Vasculitis. [PDF]

ACR Open Rheumatol, 2020
Merkel PA, Niles J, Jimenez R, Spiera RF, Rovin BH, Bomback A, Pagnoux C, Potarca A, Schall TJ, Bekker P, CLASSIC Investigators.   +10 more
europepmc   +1 more source