Results 161 to 170 of about 1,253,157 (246)

Retro‐Hetero‐Michael Addition Strategies in Organic Synthesis

European Journal of Organic Chemistry, Volume 29, Issue 32, 24 August 2026.
In this review, synthetic approaches to carbo‐ and heterocyclic compounds, including natural products, published in the last 15 years (2011–2025) which have either relied upon or included a retro‐hetero‐Michael addition step at any stage are discussed.
Dina Scarpi, Ernesto G. Occhiato
wiley   +1 more source

Role of the C5a-C5a receptor axis in the inflammatory responses of the lungs after experimental polytrauma and hemorrhagic shock. [PDF]

Sci Rep, 2021
Chakraborty S, Winkelmann VE, Braumüller S, Palmer A, Schultze A, Klohs B, Ignatius A, Vater A, Fauler M, Frick M, Huber-Lang M.   +10 more
europepmc   +1 more source

Inhibition of complement C5a receptor protects lung cells and tissues against lipopolysaccharide-induced injury via blocking pyroptosis. [PDF]

Aging (Albany NY), 2021
Wang R, Wang Y, Hu L, Lu Z, Wang X.
europepmc   +1 more source

A Multicenter, Open‐Label, Phase 2 Trial Comparing Crizanlizumab Combined With Standard Therapy to Standard Therapy Alone on Renal Function in Patients With Sickle Cell Nephropathy (STEADFAST)

American Journal of Hematology, Volume 101, Issue 10, Page 2666-2671, October 2026.
Kenneth I. Ataga, Pablo Bartolucci, Santosh L. Saraf, Vimal K. Derebail, Adlette Inati, Jeffrey D. Lebensburger, Laurie DeBonnett, Rodolfo D. Cancado, Claire C. Sharpe   +8 more
wiley   +1 more source

Structural insights into ligand-recognition, activation, and signaling-bias at the complement C5a receptor, C5aR1

, 2023
Saha S, Maharana J, Yadav MK, Sarma P, Singh V, Mohapatra S, Soni C, Saha S, Mishra S, Ganguly M, Chami M, Banerjee R, Shukla AK.   +12 more
europepmc   +1 more source

Folic acid-mediated fibrosis is driven by C5a receptor 1-mediated activation of kidney myeloid cells.

Am J Physiol Renal Physiol, 2022
Sahu RK, Xavier S, Chauss D, Wang L, Chew C, Taylor R, Stallcup WB, Ma JZ, Kazemian M, Afzali B, Köhl J, Portilla D.   +11 more
europepmc   +1 more source

Submolecular probing of the complement C5a receptor-ligand binding reveals a cooperative two-site binding mechanism. [PDF]

Commun Biol, 2020
Dumitru AC, Deepak RNVK, Liu H, Koehler M, Zhang C, Fan H, Alsteens D.   +6 more
europepmc   +1 more source

Effect of C5a Receptor Antagonist on the Osteogenic Differentiation of Dental Pulp Stem Cells. [PDF]

Clin Exp Dent Res
Tan X, Hu J, Li J, Chen Z, Shi X, Liu J, Liu M, Hu W.   +7 more
europepmc   +1 more source

Complement C5a receptor 1 antagonist attenuates alveolar hypoplasia induced by pulmonary hypoperfusion and its underlying mechanisms. [PDF]

Front Immunol
Liu C, Zheng S, Wang Y, Wang Z, Li D, Li H, Xue Y, Wang Z, She S, Ye L, Ruan P, Fu L, Sun Q.   +12 more
europepmc   +1 more source

Renal Expression Levels of C5a Receptor and Autophagy-related Beclin-1 and LC3A/B Are Simultaneously Enhanced Under Immunoglobulin Treatment in a Rat Model of Sepsis. [PDF]

In Vivo
Polat Ö, Orhun G, Anakli I, Yilmaz V, Koral G, Ulusoy C, Canbaz M, Ozcan PE, Tüzün E, Esen F.   +9 more
europepmc   +1 more source