Results 181 to 190 of about 1,253,157 (246)

C5a Mutants Are Potent Antagonists of the C5a Receptor (CD88) and of C5L2 [PDF]

Journal of Biological Chemistry, 2004
Magnus Otto, Heiko Hawlisch, Peter N. Monk, Melanie Müller, Andreas Klos, Christopher L. Karp, Jörg Köhl   +6 more
openaire   +1 more source

Blockade of the Complement C5a Receptor Reduces Incisional Allodynia, Edema, and Cytokine Expression.

Background: Activation of the complement system is one component of the inflammatory response. Various components of the complement system participate in killing foreign organisms, recruiting immune cells, enhancing edema, and stimulating cytokine ...
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core  

Blockade of C5a receptor unleashes tumor-associated macrophage antitumor response and enhances CXCL9-dependent CD8⁺ T cell activity. [PDF]

Mol Ther
Luan X, Lei T, Fang J, Liu X, Fu H, Li Y, Chu W, Jiang P, Tong C, Qi H, Fu Y.   +10 more
europepmc   +1 more source

Toxoplasma Infection Induces Sustained Up-Regulation of Complement Factor B and C5a Receptor in the Mouse Brain via Microglial Activation: Implication for the Alternative Complement Pathway Activation and Anaphylatoxin Signaling in Cerebral Toxoplasmosis. [PDF]

Front Immunol, 2020
Shinjyo N, Hikosaka K, Kido Y, Yoshida H, Norose K.   +4 more
europepmc   +1 more source

LukS-PV induces apoptosis in acute myeloid leukemia cells mediated by C5a receptor. [PDF]

Cancer Med, 2019
Zhang P, Yu WW, Peng J, Xu LF, Zhao CC, Chang WJ, Ma XL, Ma XL.   +7 more
europepmc   +1 more source

N-Acetylcysteine Attenuates Cisplatin-Induced Acute Kidney Injury by Inhibiting the C5a Receptor. [PDF]

Biomed Res Int, 2019
Huang S, You J, Wang K, Li Y, Zhang Y, Wei H, Liang X, Liu Y.   +7 more
europepmc   +1 more source

Corrigendum to "The Controversial C5a Receptor C5aR2: Its Role in Health and Disease". [PDF]

J Immunol Res, 2017
Zhang T, Garstka MA, Li K.
europepmc   +1 more source

Randomized Trial of C5a Receptor Inhibitor Avacopan in ANCA-Associated Vasculitis. [PDF]

J Am Soc Nephrol, 2017
Jayne DRW, Bruchfeld AN, Harper L, Schaier M, Venning MC, Hamilton P, Burst V, Grundmann F, Jadoul M, Szombati I, Tesař V, Segelmark M, Potarca A, Schall TJ, Bekker P, CLEAR Study Group.   +15 more
europepmc   +1 more source

PLCβs are recruited to the plasma membrane in macrophages by both Gβγ and Gα_q. [PDF]

Proc Natl Acad Sci U S A
Falzone ME, Banerjee P, MacKinnon R.
europepmc   +1 more source

Intratumoral C3ar/C5ar1 Antagonists Imbedded in an In Situ Forming Implant Can Robustly Suppress Solid Tumors. [PDF]

Cells
Choi YA, Konrad R, Pohlmann ES, Abenojar E, Exner A, Medof ME.   +5 more
europepmc   +1 more source