Results 141 to 150 of about 2,358,049 (278)
Adjunctive Therapies in Periodontitis: Current Concepts and the Future
Journal of Periodontal Research, EarlyView.This graphical abstract summarizes the translational pathway from preclinical research to clinical implementation of adjunctive therapies for periodontitis, highlighting key barriers, innovative therapeutic strategies, and emerging tools that aim to bridge experimental discoveries with patient care.
Rafael Scaf de Molon +4 more
wiley +1 more source
Increased Expression of Anaphylatoxin C5a-Receptor-1 in Neutrophils and Natural Killer Cells of Preterm Infants. [PDF]
Int J Mol Sci, 2023 Boeckel H +6 more
europepmc +1 more source
The C5a Receptor (C5aR) C5L2 Is a Modulator of C5aR-mediated Signal Transduction*
Journal of Biological Chemistry, 2009 The complement anaphylatoxin C5a is a proinflammatory component of host defense that functions through two identified receptors, C5a receptor (C5aR) and C5L2.
Claire E. Bamberg +11 more
semanticscholar +1 more source
ResearchDespite the effectiveness of epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) in treating lung adenocarcinoma with epidermal growth factor receptor (EGFR) mutations, many patients eventually stop responding to therapy.
Yuchen Zhang +6 more
doaj +1 more source
C5a receptor expression in T lymphocytes [PDF]
Journal of Leukocyte Biology, 2007 Connelly et al. [1] have published in a recent paper that C5a receptor expression in murine T lymphocytes is inducible under certain experimental conditions. Their conclusions rely exclusively on immunophenotyping by flow cytometry using a single mAb (20/70). In Acknowledgments, it is declared that “We are grateful to Dr.
openaire +2 more sources
Periodontitis and rheumatoid arthritis—Global efforts to untangle two complex diseases
Periodontology 2000, EarlyView.Abstract Understanding the impact of oral health on rheumatoid arthritis (RA) will inform how best to manage patients with both periodontitis and RA. This review seeks to provide an update on interventional and mechanistic investigations, including a brief summary of European Research programs investigating the link between periodontitis and RA. Recent
Isabel Lopez‐Oliva +2 more
wiley +1 more source
Anaphylatoxin C5a receptor signaling induces mitochondrial fusion and sensitizes retinal pigment epithelial cells to oxidative stress. [PDF]
Biochim Biophys Acta Gen Subj, 2023 Ishii M, Rohrer B.
europepmc +1 more source
Veterinary Dermatology, EarlyView.Background: Canine atopic dermatitis (cAD) is a common, chronic skin condition characterised by epidermal barrier dysfunction, immune dysregulation and cutaneous dysbiosis. While “emollient plus” formulations are widely used in human atopic dermatitis, their role in cAD remains underexplored. Hypothesis/Objectives: To evaluate the clinical efficacy and
Beatriz Fernandes +8 more
wiley +1 more source
The Role of Formylpeptide Receptors, C5a Receptors, and Cytosolic-Free Calcium in Neutrophil Priming [PDF]
, 2017 Polymorphonuclear leukocytes (PMNL) exposed to chemoattractants or cytokines change their functional capacity. The effect of endotoxin-activated serum as a priming agent on humanPMNL was tested. PretreatmentofPMNL with endotoxin-activated serum increased
Dahinden, Clemens A. +2 more
core
Veterinary Dermatology, EarlyView.Background: DNA‐based vaccination rapidly induces strong cellular and humoral immune responses, which may be enhanced by inclusion of lysosomal‐associated membrane protein‐1 (LAMP). Objectives: This proof‐of‐concept study evaluated the efficacy and safety of a Der f 2/Zen 1‐LAMP‐based DNA vaccine immunotherapy in client‐owned dogs with nonseasonal AD ...
Petra Bizikova +6 more
wiley +1 more source