Results 121 to 130 of about 16,368 (183)

Generation of two iPSC lines from ALS patients harboring C9orf72 hexanucleotide repeat expansions. [PDF]

Stem Cell Res
Wu D, Kojic A, Ross JP, Li D, Walther P, Goyal N, Sampson J, Wu JC.   +7 more
europepmc   +1 more source

Genetic frontotemporal degeneration across the lifespan? A critical appraisal of the neurodevelopmental hypothesis. [PDF]

Alzheimers Dement
So I, Birkle TJY, Duff KE, Restrepo-Martinez M, Ducharme S, Finger EC.   +5 more
europepmc   +1 more source

Caractérisation d'un modèle murin knock out pour le gène C9orf72

, 2019
An expansion of G4C2 repeats in C9ORF72 gene is the most common genetic cause of amyotrophic lateral sclerosis (ALS). These repeats lead to DNA epigenetic changes resulting in a decrease expression of C9ORF72.
Corbier, Camille
core  

Glial cell toxicity in a Drosophila C9orf72 neurodegeneration model. [PDF]

PLoS Genet
Hubbard I, Dubnau J.
europepmc   +1 more source

Characterization of a C9orf72 knock out mouse model

, 2019
Une expansion de répétitions G4C2 dans le gène C9ORF72 est la cause génétique la plus commune de la sclérose latérale amyotrophique (SLA). Afin d’étudier les conséquences de la perte d’expression de C9ORF72, nous avons généré un modèle murin knockout ...
Corbier, Camille
core  

Multiplex Panel Detects Glial and Inflammatory Biomarker Signatures in Sporadic and C9orf72-ALS. [PDF]

Neurol Neuroimmunol Neuroinflamm
Baskar K, Steffke C, Bernsen S, Elmas Z, Hesebeck-Brinckmann J, Schuster J, Meyer T, Weydt P, Weishaupt J, Brenner D, Catanese A.   +10 more
europepmc   +1 more source

Microglial Dysfunction Induced by C9ORF72 Dipeptide Repeat Proteins: Biomarker and Therapeutic Perspectives. [PDF]

Int J Mol Sci
Sharma N, An SSA.
europepmc   +1 more source

Plasma Proteomic Changes in GRN and C9orf72 Frontotemporal Dementia. [PDF]

Eur J Neurol
Simrén J, Benedet AL, Di Molfetta G, Pola I, Tan K, Cantoni V, Libri I, Rivolta J, Ghidoni R, Zetterberg H, Borroni B, Ashton NJ.   +11 more
europepmc   +1 more source

Distinct brain extracellular vesicle microRNA profiles differ in frontotemporal dementia and Alzheimer's disease. [PDF]

Brain Commun
Morgan J, Aarons T, Mukhopadhyay A, Lace G.   +3 more
europepmc   +1 more source

Changes in body composition in genetic C9orf72 carriers: The role of the hypothalamus and thalamus. [PDF]

Alzheimers Dement
Ahmed RM, Tse NY, Bocchetta M, Dobson-Stone C, Kwok JB, Hodges JR, Irish M, Rohrer JR, Piguet O, Halliday G.   +9 more
europepmc   +1 more source