Results 141 to 150 of about 16,368 (183)

Recurrent patterns of TOP1-mediated neuronal genomic damage shared by major neurodegenerative disorders. [PDF]

Cell
Zhou Z, Luquette LJ, Dong G, Kim J, Ku J, Kim K, Ramesh N, Bae M, Caplin A, Shao DD, Sahile B, Essuman K, Goodman E, Miller MB, Huang AY, Nathan WJ, Nussenzweig A, Park PJ, Lagier-Tourenne C, Lee EA, Walsh CA.   +20 more
europepmc   +1 more source

Two dipeptide repeat proteins are produced from mammalian telomeric RNA previously thought to be a long non-coding RNA. [PDF]

RNA Biol
Al-Turki TM, Griffith JD.
europepmc   +1 more source

Intrathecal (G₄C₂)₁₄₉ delivery in C9orf72-deficient mice yields mild motor dysfunction and ALS/FTD pathological hallmarks. [PDF]

Acta Neuropathol Commun
Russell KA, Shahrabi AA, Akerman SC, Byrne MD, Rothstein JD, Trotti D, Jensen BK, Haeusler AR.   +7 more
europepmc   +1 more source

Global transcriptional changes across multiple isogenic <i>C9orf72</i> patient iPSC-derived neurons. [PDF]

iScience
Sreeram A, Baron DM, Brusati A, Stallworth K, Humphrey J, Landers JE.   +5 more
europepmc   +1 more source

Composite grey matter fingerprints for genetic frontotemporal dementia. [PDF]

J Neurol Neurosurg Psychiatry
Bouzigues A, Campana G, Joulot M, Gensollen N, Russell LL, Foster PH, Ferry-Bolder E, Van Swieten JC, Jiskoot LC, Seelaar H, Sánchez-Valle R, Laforce R, Graff C, Galimberti D, Vandenberghe R, de Mendonca A, Tiraboschi P, Santana I, Gerhard A, Levin J, Sorbi S, Otto M, Bertoux M, Lebouvier T, Ducharme S, Butler C, Finger E, Tartaglia MC, Masellis M, Rowe JB, Synofzik M, Moreno F, Borroni B, Leber I, Zanusso G, Rohrer JD, Migliaccio R, GENetic Frontotemporal dementia Initiative (GENFI).   +37 more
europepmc   +1 more source

RAN Translation-Coupled Decay of the <i>C9orf72</i> GGGGCC Repeat Transcript by the RNA Exosome Suppresses Dipeptide Repeat Production. [PDF]

Int J Mol Sci
Wu Y, Li L, Tian J, Liu L, Du K, Shao Z, Cheng T, Cao X, Wang T.   +8 more
europepmc   +1 more source

Update and recommendations on genetic testing for amyotrophic lateral sclerosis in clinical practice: a Brazilian expert view. [PDF]

Front Neurol
Sgobbi P, de Rezende Pinto WBV, Seneor DD, Orsini M, Chieia MAT, Oliveira ASB.   +5 more
europepmc   +1 more source

Protein-First, but Not Protein-Only: Rethinking Neurodegenerative Diseases Through Transgenic Mouse Models. [PDF]

Neurol Int
Zeng CW.
europepmc   +1 more source

Systematic proteomics reveals plasma NEFL as a robust predictor and pathological associate in <i>C9ORF72</i>-related neurodegeneration. [PDF]

Front Aging Neurosci
Hu Z, Wan JJ, Yan QQ, Fan Y, Liu J.
europepmc   +1 more source

Distinct proteomic CSF profiles in genetic frontotemporal lobar degeneration. [PDF]

Brain
De Houwer JFH, Dopper EG, van Buuren R, Stokkel M, de Boer L, Swartenbroekx T, Boesjes PA, Rajicic A, Sogorb-Esteve A, Bouzigues A, Russell LL, Foster PH, Ferry-Bolder E, van Swieten JC, Jiskoot LC, Sanchez-Valle R, Laforce R, Graff C, Galimberti D, Vandenberghe R, de Mendonça A, Tiraboschi P, Santana I, Gerhard A, Levin J, Nacmias B, Otto M, Bertoux M, Lebouvier T, Ducharme S, Butler CR, Le Ber I, Finger E, Tartaglia MC, Masellis M, Rowe JB, Synofzik M, Moreno F, Borroni B, Zetterberg H, Rohrer JD, Tijms BM, Pijnenburg YAL, Teunissen C, Seelaar H, GENFI Consortium Members.   +45 more
europepmc   +1 more source