Results 171 to 180 of about 16,368 (183)

The C9orf72 protein interacts with Rab1a and the ULK1 complex to regulate initiation of autophagy

EMBO Journal, 2016
Andrew Grierson, Laura Ferraiuolo, Alexander J. Whitworth   +2 more
exaly  

Toxic PR Poly-Dipeptides Encoded by the C9orf72 Repeat Expansion Target LC Domain Polymers

Cell, 2016
Yi Lin, Masato Kato, Ilmin Kwon
exaly  

Neuroimaging signatures of frontotemporal dementia genetics: C9ORF72, tau, progranulin and sporadics.

Brain, 2012
Jennifer L Whitwell, Dennis W. Dickson, Clifford Jack   +2 more
exaly  

Pattern of ubiquilin pathology in ALS and FTLD indicates presence of C9ORF72 hexanucleotide expansion

Acta Neuropathologica, 2012
Mervyn J Monteiro, Edward B Lee, David J. Irwin   +2 more
exaly  

Loss of C9ORF72 impairs autophagy and synergizes with polyQ Ataxin‐2 to induce motor neuron dysfunction and cell death

EMBO Journal, 2016
Nicolas Charlet, Mustapha Oulad-Abdelghani, Edor Kabashi   +2 more
exaly  

G‐quadruplex‐binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo

EMBO Molecular Medicine, 2018
W David Wilson, Mohamed A. Ismail, Andrea Calvo   +2 more
exaly  

C9orf72 loss-of-function: a trivial, stand-alone or additive mechanism in C9 ALS/FTD?

Acta Neuropathologica, 2020
Elke Braems, Bart Swinnen, Ludo Van Den Bosch   +2 more
exaly  

A C9ORF72/SMCR8-containing complex regulates ULK1 and plays a dual role in autophagy

Science Advances, 2016
Kunchithapadam Swaminathan, Fan Lai, Stephanie Herrlinger   +2 more
exaly  

Novel clinical associations with specific C9ORF72 transcripts in patients with repeat expansions in C9ORF72

Acta Neuropathologica, 2015
Dennis W. Dickson, Melissa E. Murray, Jie Jiang   +2 more
exaly  

C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles

Cell, 2016
Bing Bai, Brian A. Maxwell, Timothy Shaw
exaly