Results 171 to 180 of about 202,389 (291)

In Vivo Direct Reprogramming: Current Progress and Future Prospects from Mechanisms to Therapeutic Application

Advanced Science, EarlyView.
This review examines the potential of in vivo direct reprogramming in regenerative medicine for functional tissue restoration, highlighting the role of tissue‐resident cues in generating functionally mature reprogrammed cells from lineage‐related cells. It contains a discussion on mechanisms, reprogramming factors, delivery approaches, and applications
Rishabh Deo Singh, Mauro Calvoli, Kyeong Kyu Kim   +2 more
wiley   +1 more source

Perturbation of Anion/Cation Transport Leads to Apical Panicle Abortion in Rice by Disrupting Ca²⁺ Homeostasis. [PDF]

Plant Biotechnol J
Liu B, Luo S, Tian W, Liu X, Zhang J, Ren Y, Liu Z, Shao J, Chang Y, Cheng Z, Wan J.   +10 more
europepmc   +1 more source

bFGF-like Activity Supported Tissue Regeneration, Modulated Neuroinflammation, and Rebalanced Ca²⁺ Homeostasis following Spinal Cord Injury. [PDF]

Int J Mol Sci, 2023
Ardizzone A, Bova V, Casili G, Filippone A, Lanza M, Repici A, Esposito E, Paterniti I.   +7 more
europepmc   +1 more source

Matrix Stiffness Orchestrates Mesenchymal Stem Cell Lineage Commitment Toward Osteogenesis and Adipogenesis Through the PIEZO1/SP1/STC2 Axis

Advanced Science, EarlyView.
Matrix stiffness directs mesenchymal stem cell lineage commitment through PIEZO1‐dependent activation of the SP1/STC2 pathway. Stiff matrices favor osteogenesis and suppress adipogenesis, whereas the loss of PIEZO1 function impairs early bone formation. STC2 retains lineage‐regulatory activity even when PIEZO1 is inactive.
Shuo Zhang, Siteng Li, Wenzhong Chen, Qingcheng Song, Haiyue Zhao, Peng Wang, Yiran Zhang, Wenquan Liang, Shaowei Zheng, Juan Wang, Wei Chen, Yanbin Zhu, Yingze Zhang   +12 more
wiley   +1 more source

Monitoring Lysosomal Viscosity in Hyperglycemia in Association with Ca²⁺ Homeostasis and Alzheimer's Disease Using a Fluorescent Zn-Metal Complex. [PDF]

Chem Biomed Imaging
Salam A, Mukherjee B, Sapkal GT, Nandi CK.   +3 more
europepmc   +1 more source

The endoplasmic reticulum-plasma membrane tethering protein TMEM24 is a regulator of cellular Ca2+ homeostasis.

J Cell Sci, 2022
Xie B, Panagiotou S, Cen J, Gilon P, Bergsten P, Idevall-Hagren O.   +5 more
europepmc   +1 more source

Enhancing Muscle Intracellular Ca²⁺ Homeostasis and Glucose Uptake: Passive Pulsatile Shear Stress Treatment in Type 2 Diabetes. [PDF]

Biomedicines, 2023
Uryash A, Umlas J, Mijares A, Adams JA, Lopez JR.   +4 more
europepmc   +1 more source

Melanin has a role in Ca2+ homeostasis in human melanocytes

, 2003
We have examined whether melanin affects Ca2+ homeostasis in cultured normal human melanocytes. Intracellular Ca2+ concentrations ([Ca2+]i), were measured in four Caucasian and in three Negroid melanocyte cultures.
Van Der Laarse A, Hoogduijn MJ, Wood JM, Thody AJ, Van Nieuwpoort AF, Smit NP   +5 more
core  

Electronics‐Free Visual Monitoring of Dry Eye Disease‐Related Tear Biomarkers Using Smart Scleral Lenses

Advanced Science, EarlyView.
An electronics‐free smart scleral lens passively monitors dry eye disease‐related tear biomarkers through colorimetric sensing of chloride, pH, and ocular surface temperature. Smartphone‐assisted image analysis enables quantitative interpretation, providing a simple, non‐invasive strategy for ocular health monitoring without integrated electronics ...
Ziheng Wang, Sang Mok Park, Dawn Meyer, Seul Ah Lee, Yumin Dai, Tianhao Yu, Taewoong Park, Feiyang Li, Jason Gerard Jedlicka, Tristan Michael Long, Oluwabunmi T. Oladele, Gillian C. Shaw, Shin Ae Park, Pete S. Kollbaum, Young L. Kim, Chi Hwan Lee   +15 more
wiley   +1 more source

Mitochondrial Ca²⁺ Homeostasis: Emerging Roles and Clinical Significance in Cardiac Remodeling. [PDF]

Int J Mol Sci, 2022
Zhang D, Wang F, Li P, Gao Y.
europepmc   +1 more source