Results 31 to 40 of about 202,389 (291)
STAR Protocols, 2021 Summary: Calcium regulation is a critical process in neurons, and Ca2+ signaling is a major contributor to neurological disorders including Parkinson’s disease (PD).
Xiling Yin +4 more
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Frontiers in Cell and Developmental Biology, 2022 Although anything that changes spatiotemporally could be a signal, cells, particularly neurons, precisely manipulate calcium ion (Ca2+) to transmit information. Ca2+ homeostasis is indispensable for neuronal functions and survival.
Dong-Xu Huang +7 more
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Frontiers in Neuroscience, 2023 Calcium (Ca2+) comprises a critical ionic second messenger in the central nervous system that is under the control of a wide array of regulatory mechanisms, including organellar Ca2+ stores, membrane channels and pumps, and intracellular Ca2+-binding ...
Benjamin Klocke +5 more
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Studies on the role of Coronin 1 and the actin cytoskeleton in T cell signaling and survival [PDF]
, 2009 Calcium ions (Ca2+) function as universal second messengers in most if not all eukaryotic cells, including the cells of the immunesystem. Ca2+ signals are required for the proper activation of lymphocytes, such as T-lymphocytes, their proliferation ...
Müller, Philipp
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Decoding the influence of mitochondrial Ca2+ regulation on neurodegenerative disease progression
Mitochondrial CommunicationsMitochondria are pivotal hubs in maintaining cellular homeostasis, encompassing vital processes such as bioenergetics, redox regulation, Ca2+ signaling, and programmed cell death.
Jianxu Sun +4 more
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Roles of Calcium Regulating MicroRNAs in Cardiac Ischemia-Reperfusion Injury
Cells, 2014 Cardiac Ca2+ cycling and signaling are closely associated with cardiac function. Changes in cellular Ca2+ homeostasis may lead to aberrant cardiac rhythm and may play a critical role in the pathogenesis of cardiac diseases, due to their exacerbation of ...
Eunhyun Choi, Min-Ji Cha, Ki-Chul Hwang
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iScienceSummary: Magnesium (Mg2+) is crucial for several cellular and physiological processes and is tightly regulated due to health risks associated with imbalances.
Pritha Dutta, Anita T. Layton
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Mitochondrial calcium regulation during and following contractions in skeletal muscle
Journal of Physical Fitness and Sports Medicine, 2018 In skeletal muscle, resting cytosolic Ca2+ concentration ([Ca2+]cyto) homeostasis is exquisitely regulated by Ca2+ transport across the sarcolemmal, mitochondrial and sarcoplasmic reticulum (SR) membranes.
Hiroaki Eshima +2 more
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Targeting Ca2 + Handling Proteins for the Treatment of Heart Failure and Arrhythmias
Frontiers in Physiology, 2020 Diseases of the heart, such as heart failure and cardiac arrhythmias, are a growing socio-economic burden. Calcium (Ca2+) dysregulation is key hallmark of the failing myocardium and has long been touted as a potential therapeutic target in the treatment ...
Alexandra Njegic +4 more
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Exocytosis of ATP from astrocytes modulates phasic and tonic inhibition in the neocortex [PDF]
, 2014 Communication between neuronal and glial cells is important for many brain functions. Astrocytes can modulate synaptic strength via Ca2+-stimulated release of various gliotransmitters, including glutamate and ATP. A physiological role of ATP release from
Lalo, Ulyana +17 more
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