Mitochondrial Ca2+ homeostasis in health and disease
Although it has long been known that mitochondria possess a complex molecular repertoire for accumulating and releasing Ca2+, only in recent years has a large body of data demonstrated that these organelles promptly respond to Ca(2+)-mediated cell stimulations.
CAMPANELLA M +2 more
openaire +8 more sources
TRPV5, the Gateway to Ca2+ Homeostasis [PDF]
Ca2+ homeostasis in the body is tightly controlled, and is a balance between absorption in the intestine, excretion via the urine, and exchange from bone. Recently, the epithelial Ca2+ channel (TRPV5) has been identified as the gene responsible for the Ca2+ influx in epithelial cells of the renal distal convoluted tubule.
Mensenkamp, A.R. +2 more
openaire +5 more sources
Ca2+ signals co-ordinate zygotic polarization and cell cycle progression in the brown alga, Fucus serratus. [PDF]
Zygotes of the fucoid brown algae provide excellent models for addressing fundamental questions about zygotic symmetry breaking. Although the acquisition of polarity is tightly coordinated with the timing and orientation of the first asymmetric division ...
Bothwell, John H. F. +4 more
core +5 more sources
Neuronal ageing in long-term cultures: Alterations of ca2+ homeostasis
Deficiencies of Ca2+ homeostasis are proposed to play an important role in neuronal ageing and/or neurodegeneration. The aim of this study was to investigate, in a defined neuronal population, primary cerebellar granule neuron culture, the time-dependent
Toescu, Emil C. +1 more
core +10 more sources
Inter-Organellar Ca<sup>2+</sup> Homeostasis in Plant and Animal Systems. [PDF]
The regulation of calcium (Ca2+) homeostasis is a critical process in both plant and animal systems, involving complex interplay between various organelles and a diverse network of channels, pumps, and transporters.
Steiner P, Zierler S.
europepmc +2 more sources
Calcium homeostasis and role of ryanodine receptor type 1 (RyR1) in immune cells [PDF]
Ryanodine receptors are intracellular Ca2+ release channels located in the membrane of the Endoplasmatic/Sarcoplasmatic Reticulum. Ryanodine receptor 1 isoform is preferentially expressed in skeletal muscle where it is responsible for release of Ca2 ...
Vukcevic, Mirko
core +1 more source
GTP and Ca2+ Modulate the Inositol 1,4,5-Trisphosphate-Dependent Ca2+ Release in Streptolysin O-Permeabilized Bovine Adrenal Chromaffin Cells [PDF]
The inositol 1,4,5-trisphosphate (IP3)-induced Ca2+ release was studied using streptolysin O-permeabilized bovine adrenal chromaffin cells. The IP3-induced Ca2+ release was followed by Ca2+ reuptake into intracellular compartments.
Föhr, K. J. +9 more
core +1 more source
Ca2+ signalling and homeostasis during colony initiation in Neurospora crassa [PDF]
Calcium is a highly versatile intracellular signal molecule that can regulate numerous different cellular functions. In filamentous fungi there is evidence for it being involved in regulating various processes, including spore germination, hyphal tip ...
Chu, Meiling
core +3 more sources
Intracellular calcium (Ca2+) is crucial for signal transduction in Cryptococcus neoformans, the major cause of fatal fungal meningitis. The calcineurin pathway is the only Ca2+-requiring signaling cascade implicated in cryptococcal stress adaptation and ...
Eamim Daidrê Squizani +10 more
doaj +1 more source
Intracellular zinc modulates cardiac ryanodine receptor-mediated calcium release [PDF]
This work was supported by University of St. Andrews, Tenovus Scotland Grant T14/35 (to S. J. P.), British Heart Foundation Grant FS/14/69/31001 (to S. J.
Woodier, Jason +7 more
core +1 more source

