Results 11 to 20 of about 110,913 (348)
QJM: An International Journal of Medicine, 2005 Cancer cachexia is a severe debilitating disorder for which there are currently few therapeutic options. It is driven by the release of pro-inflammatory cytokines and cachectic factors by both host and tumour. Over the past few years, basic science advances have begun to reveal the breadth and complexity of the immunological mechanisms involved, and in
J N, Gordon, S R, Green, P M, Goggin
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Journal of Cachexia, Sarcopenia and Muscle, 2023 Chronic diseases often lead to metabolic disorders, causing anabolic resistance and increased energy consumption, which result in cachexia. Cachexia, in turn, can lead to major clinical consequences such as impaired quality of life, shortened life ...
H. Arai +38 more
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Journal of Cachexia, Sarcopenia and Muscle, 2023 Cancer cachexia is a systemic hypoanabolic and catabolic syndrome that diminishes the quality of life of cancer patients, decreases the efficiency of therapeutic strategies and ultimately contributes to decrease their lifespan.
Agnes Martin +2 more
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Journal of Hematology & Oncology, 2023 Background Cancer cachexia is a deadly wasting syndrome that accompanies various diseases (including ~ 50% of cancers). Clinical studies have established that cachexia is not a nutritional deficiency and is linked to expression of certain proteins ( e.g.
Dong Wang +12 more
semanticscholar +1 more source
Journal of Parenteral and Enteral Nutrition, 1988 Cancer cachexia describes a syndrome of progressive weight loss, anorexia, and persistent erosion of host body cell mass in response to a malignant growth. Although often associated with preterminal patients bearing disseminated disease, cachexia may be present in the early stages of tumor growth before any signs or symptoms of malignancy. A decline in
K A, Kern, J A, Norton
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Cancer Cachexia: New Insights and Future Directions
Cancers, 2023 Simple Summary Cancer is a major burden of disease worldwide, with cancer cachexia being a poor prognosis factor which leads to a decreased quality of life and overall survival.
Claudia Raluca Mariean +3 more
semanticscholar +1 more source
Nutrients, 2021 The recent publication of the revised Consensus on definition and diagnosis of sarcopenia (EWGSOP2) and the Global Leadership Initiative on Malnutrition (GLIM) criteria changed the approach to research on sarcopenia and malnutrition. Whilst sarcopenia is
Delky Meza-Valderrama +6 more
semanticscholar +1 more source
Cancer Medicine, 2023 Background The presence of cachexia negatively impacts the prognosis of patients with cancer. However, the mechanisms behind the development of cachexia and its prognostic impact on immunotherapy efficacy are not fully understood.
Daiki Murata +8 more
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Cachexia in Cancer Patients: Systematic Literature Review
Asian Journal of Oncology, 2020 Introduction Cachexia in cancer patients, especially in advanced stage, is recently known as an emerging problem. Cachexia occurs in about half of all patients with neoplastic disease.
Timotius I. Hariyanto, Andree Kurniawan
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Pancreatic cancer cachexia: a review of mechanisms and therapeutics. [PDF]
, 2014 Over the last decade, we have gained new insight into the pathophysiology of cachexia associated with pancreatic cancer. Unfortunately, its treatment is complex and remains a challenge.
Andrew Eugene Hendifar +8 more
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