Results 41 to 50 of about 93,078 (303)
Implications of skeletal muscle loss for public health nutrition messages:a brief report [PDF]
, 2015 Age-related skeletal muscle loss, sarcopenia, cachexia and wider malnutrition (under nutrition) are complex in aetiology with interaction of clinical, social and economic factors.
Levy, Louis B, Welch, Ailsa A
core +1 more source
EMBO Molecular MedicineCancer cachexia is a debilitating syndrome characterized by the progressive loss of skeletal muscle mass with or without fat loss. Recent studies have implicated dysregulation of the endoplasmic reticulum (ER) stress-induced unfolded protein response ...
Aniket S Joshi +5 more
doaj +1 more source
Myostatin/Smad2/Smad3 pathway define a differential clinical phenotype in COPD-associated sarcopenia
ERJ Open ResearchBackground Sarcopenia, defined as the loss of muscle mass and function, represents one of the most relevant comorbidities in patients with COPD even at early stages.
Adriana Núñez-Robainas +4 more
doaj +1 more source
Drosophila as a model system to study nonautonomous mechanisms affecting tumour growth and cell death [PDF]
, 2018 The study of cancer has represented a central focus in medical research for over a century. The great complexity and constant evolution of the pathology require the use of multiple research model systems and interdisciplinary approaches.
Cordero, Julia B. +2 more
core +3 more sources
Cell, 2010 Muscle atrophy (cachexia) in cancer patients is a life-threatening condition for which therapeutic options are limited. Zhou et al. (2010) now identify a new target for treating cachexia, the activin type-2 receptor (ActRIIB). In several mouse models of cachexia, the authors reversed wasting of skeletal and cardiac muscle and increased life span by ...
openaire +2 more sources
Clinical Insights Into Hypercalcemia of Malignancy in Childhood
Pediatric Blood &Cancer, EarlyView.ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley +1 more source
Of faeces and sweat. How much a mouse is willing to run: having a hard time measuring spontaneous physical activity in different mouse sub-strains [PDF]
, 2017 Physical activity has multiple beneficial effects in the physiology and pathology of the organism. In particular, we and other groups have shown that running counteracts cancer cachexia in both humans and rodents.
Adamo, Sergio +2 more
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Dietary Protein Intake and Peritoneal Protein Losses in Peritoneal Dialysis Patients
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Peritoneal dialysis (PD) patients lose protein in their waste dialysate, potentially increasing their risk for malnutrition. We wished to determine whether there was any association between losses and dietary protein intake (DPI). Methods DPI was assessed from 24‐h dietary recall using Nutrics software.
Haalah Shaaker, Andrew Davenport
wiley +1 more source
The impact of cachexia on dietary intakes, symptoms, and quality of life in advanced cancer
JCSM Rapid Communications, 2022 Background The relationships between cachexia stages and the Functional Assessment of Anorexia/Cachexia Therapy Anorexia Cachexia Subscale (FAACT ACS) 12‐item, 5‐item anorexia symptoms, and 4‐item anorexia concerns have not been investigated in Asian ...
Koji Amano +19 more
doaj +1 more source
Storage Conditions and Passages Alter IL-6 Secretion in C26 Adenocarcinoma Cell Lines [PDF]
, 2015 The C26 adenocarcinoma tumor line is frequently used to establish peripheral tumors in mice for the study of cancer cachexia and cancer-related fatigue. Recently, we have noticed a progressive decline in the effects of tumor growth on our biological and ...
Devine, Raymond +3 more
core +3 more sources