Results 51 to 60 of about 110,913 (348)
OncoImmunology, 2021 Although previous studies suggest that cancer cachexia is a poor prognostic factor for immune checkpoint inhibitor monotherapy, the impact of cancer cachexia on chemoimmunotherapy is unclear.
Kenji Morimoto +18 more
doaj +1 more source
Heme metabolism genes Downregulated in COPD Cachexia. [PDF]
, 2020 IntroductionCachexia contributes to increased mortality and reduced quality of life in Chronic Obstructive Pulmonary Disease (COPD) and may be associated with underlying gene expression changes.
Agusti, Alvar +21 more
core +3 more sources
Journal of Cachexia, Sarcopenia and Muscle, 2023 Cachexia substantially impacts the prognosis of patients with heart failure (HF); however, there is no standard method for cachexia diagnosis. This study aimed to investigate the association of Evans's criteria, consisting of multiple assessments, with ...
E. Maekawa +27 more
semanticscholar +1 more source
The mechanical stimulation of myotubes counteracts the effects of tumor-derived factors through the modulation of the activin/follistatin ratio [PDF]
, 2019 Activin negatively affects muscle fibers and progenitor cells in aging (sarcopenia) and in chronic diseases characterized by severe muscle wasting (cachexia). High circulating activin levels predict poor survival in cancer patients. However, the relative
Adamo, Sergio +8 more
core +1 more source
Applied Biological Chemistry, 2019 Cachexia is a wasting syndrome associated with high mortality in cancer patients through inducing the failure of normal metabolism and reducing the efficacy of cancer treatment. Thus, it is critically important to diagnose cancer cachexia early.
Jae Eun Ju +7 more
doaj +1 more source
The impact of cachexia on dietary intakes, symptoms, and quality of life in advanced cancer
JCSM Rapid Communications, 2022 Background The relationships between cachexia stages and the Functional Assessment of Anorexia/Cachexia Therapy Anorexia Cachexia Subscale (FAACT ACS) 12‐item, 5‐item anorexia symptoms, and 4‐item anorexia concerns have not been investigated in Asian ...
Koji Amano +19 more
doaj +1 more source
Biomedicines, 2022 As demonstrated in COPD, bronchiectasis patients may experience respiratory and peripheral muscle dysfunction. We hypothesized that respiratory and peripheral (upper and lower limbs) muscle function and nutritional status may be more significantly ...
Xuejie Wang +7 more
doaj +1 more source
Doubled lifespan and patient‐like pathologies in progeria mice fed high‐fat diet [PDF]
, 2019 Hutchinson-Gilford Progeria Syndrome (HGPS) is a devastating premature aging disease. Mouse models have been instrumental for understanding HGPS mechanisms and for testing therapies, which to date have had only marginal benefits in mice and patients ...
Albert, Carolyn J +10 more
core +2 more sources
One-year prevalence, comorbidities and cost of cachexia-related inpatient admissions in the USA
Drugs in Context, 2014 Background: Cachexia is a condition characterized as a loss in body mass or metabolic dysfunction and is associated with several prevalent chronic health conditions including many cancers, COPD, HIV, and kidney disease, with between 10 and 50% of ...
Susan T Arthur +4 more
doaj +1 more source
A pilot study of temsirolimus and body composition. [PDF]
, 2013 PurposeBody weight and composition play a role in cancer etiology, prognosis, and treatment response. Therefore, we analyzed the weight, body composition changes, and outcome in patients treated with temsirolimus, an mTor inhibitor that has weight loss ...
Janku, Filip +6 more
core +2 more sources