Results 61 to 70 of about 110,913 (348)
Journal of Cachexia, Sarcopenia and Muscle, 2023 Patients with cancer undergoing chemotherapy experience cachexia with anorexia, body weight loss, and the depletion of skeletal muscles and adipose tissues. Effective treatment strategies for chemotherapy‐induced cachexia are scarce.
Beom Yong Lee +13 more
semanticscholar +1 more source
Journal of Cachexia, Sarcopenia and Muscle, 2018 Background Cachexia is a multifactorial syndrome that is highly prevalent in advanced cancer patients and leads to progressive functional impairments. The classification of cachexia stages is essential for diagnosing and treating cachexia. However, there
Ting Zhou +7 more
doaj +1 more source
Journal of Cachexia, Sarcopenia and Muscle, 2021 Backgrounds Hand grip strength (HGS) is one of diagnose criteria factors of sarcopenia and is associated with the survival of patients with cancer. However, few studies have addressed the association of HGS and 1 year mortality of patients with cancer ...
Mengmeng Song +16 more
doaj +1 more source
Vitamin D, a modulator of musculoskeletal health in chronic kidney disease [PDF]
, 2017 The spectrum of activity of vitamin D goes beyond calcium and bone homeostasis, and growing evidence suggests that vitamin D contributes to maintain musculoskeletal health in healthy subjects as well as in patients with chronic kidney disease (CKD ...
Jordi Bover +6 more
core +2 more sources
British Journal of Cancer, 1991 Cachexia is a common problem in the clinical management of cancer patients, particularly those with solid tumors. Cachexia is most obviously manifested as weight loss with massive depletion of both adipose tissue and muscle mass, and death is probably due to loss of lean body tissue.
openaire +5 more sources
Activation of GPR81 by lactate drives tumour-induced cachexia
Nature MetabolismCachexia affects 50–80% of patients with cancer and accounts for 20% of cancer-related death, but the underlying mechanism driving cachexia remains elusive.
Xidan Liu +19 more
semanticscholar +1 more source
Journal of Cachexia, Sarcopenia and Muscle, 2023 Changes in body composition and systemic inflammation are important characteristics of cancer cachexia. This multi‐centre retrospective study aimed to explore the prognostic value of the combination of body composition and systemic inflammation in ...
Haifeng Xie +21 more
semanticscholar +1 more source
Storage Conditions and Passages Alter IL-6 Secretion in C26 Adenocarcinoma Cell Lines [PDF]
, 2015 The C26 adenocarcinoma tumor line is frequently used to establish peripheral tumors in mice for the study of cancer cachexia and cancer-related fatigue. Recently, we have noticed a progressive decline in the effects of tumor growth on our biological and ...
Devine, Raymond +3 more
core +3 more sources
EMBO Molecular MedicineCancer cachexia is a debilitating syndrome characterized by the progressive loss of skeletal muscle mass with or without fat loss. Recent studies have implicated dysregulation of the endoplasmic reticulum (ER) stress-induced unfolded protein response ...
Aniket S Joshi +5 more
doaj +1 more source
Myostatin/Smad2/Smad3 pathway define a differential clinical phenotype in COPD-associated sarcopenia
ERJ Open ResearchBackground Sarcopenia, defined as the loss of muscle mass and function, represents one of the most relevant comorbidities in patients with COPD even at early stages.
Adriana Núñez-Robainas +4 more
doaj +1 more source