Results 291 to 300 of about 284,314 (352)

Functional Properties of Human Vascular Endothelial Cadherin (7B4/Cadherin-5), an Endothelium-Specific Cadherin

Arteriosclerosis, Thrombosis, and Vascular Biology, 1995
Abstract Human vascular endothelial cadherin (VE-cadherin, 7B4/cadherin-5) is an endothelial-specific cadherin localized at the intercellular junctions. To directly investigate the functional role of this molecule we cloned the full-length cDNA from human endothelial cells and transfected its coding region into Chinese hamster ...
Ferruccio Breviario   +2 more
exaly   +3 more sources

The E-Cadherin and N-Cadherin Switch in Epithelial-to-Mesenchymal Transition: Signaling, Therapeutic Implications, and Challenges

open access: yesCells, 2019
Epithelial-to-Mesenchymal Transition (EMT) has been shown to be crucial in tumorigenesis where the EMT program enhances metastasis, chemoresistance and tumor stemness.
Won Fen Wong   +2 more
exaly   +2 more sources

The functional activity of E-cadherin controls tumor cell metastasis at multiple steps

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2020
Significance The expression of E-cadherin has been implicated in tumor metastasis, often as a tumor suppressor, but also as a promoter of growth and metastasis.
Barry M Gumbiner, Gumbiner Barry M
exaly   +2 more sources

Aberrant N-cadherin expression in cancer

open access: yesBiomedicine and Pharmacotherapy, 2019
Neural (N)-cadherin is a calcium-dependent single-chain transmembrane glycoprotein that mediates homotypic and heterotypic cell-cell adhesion. As an important member of the cadherin family, N-cadherin plays an important role in the developmental and ...
Ping Leng
exaly   +2 more sources

The cell-cell adhesion molecule E-cadherin

open access: yesCellular and Molecular Life Sciences, 2008
Frans Van Roy, Geert Berx, Van Roy F
exaly   +2 more sources

E-cadherin: Its dysregulation in carcinogenesis and clinical implications

Critical Reviews in Oncology/Hematology, 2018
Chee-Mun Fang   +2 more
exaly   +2 more sources

Characterization of cadherin-4 and cadherin-5 reveals new aspects of cadherins

Journal of Cell Science, 1994
ABSTRACT Several properties of cadherin-4 and cadherin-5 were char- acterized by using the cDNA transfection approach. The proteins of both cadherins had a relative molecular mass of about 130 kDa and were present at the cell periphery, especially at cell-cell contact sites.
H, Tanihara   +6 more
openaire   +2 more sources

The cadherin superfamily

Journal of Cell Science, 2001
The poster provides an overview of the cadherin superfamily, depicting representative molecules for several subfamilies, and displaying the plethora of molecular arrangements characteristic of these molecules (see Commentary by Angst, Marcozzi and Magee on p. 629).
B D, Angst, C, Marcozzi, A I, Magee
openaire   +2 more sources

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