Results 241 to 250 of about 65,722 (350)

Cadherin family genes in non-small cell lung cancer: implications for diagnosis, prognosis, and targeted therapy. [PDF]

Am J Transl Res
Wang Y, Qin X, Dong W, Lei C, Zheng S, Salem MM, Bekhit MM, Almuraikhi N.   +7 more
europepmc   +1 more source

Foxo3a Suppression of Urothelial Cancer Invasiveness through Twist1, Y-Box–Binding Protein 1, and E-Cadherin Regulation

, 2010
Masaki Shiota, YooHyun Song, Akira Yokomizo, Keijiro Kiyoshima, Yasuhiro Tada, Hiroshi Uchino, Takeshi Uchiumi, Junichi Inokuchi, Yoshinao Oda, Kentaro Kuroiwa, Katsunori Tatsugami, Seiji Naito   +11 more
openalex   +2 more sources

Targeted Degradation of eEF2K by a Structure‐Guided PROTAC Strategy for the Treatment of Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study developed an eEF2K‐targeting PROTAC, A6, that efficiently degrades eEF2K in TNBC cells, inhibiting tumor growth in vitro and in vivo. To enhance tumor‐specific delivery, we engineered A6@ZIF‐8, a pH‐sensitive nanocarrier, which improved drug accumulation at tumor sites, offering a promising therapeutic strategy for TNBC through targeted ...
Shijun Cao, Changxin Zhong, Shilong Jiang, Yungui Li, Yang Xi, Mingxuan Xiao, Ting Jiang, Xiaoya Wan, Zonglin Chen, Xiaohui Yu, Yan Cheng   +10 more
wiley   +1 more source

β-Catenin: A Key Molecule in Osteoblast Differentiation. [PDF]

Biomolecules
Wróbel E, Wojdasiewicz P, Mikulska A, Szukiewicz D.   +3 more
europepmc   +1 more source

Downregulation of Bit1 expression promotes growth, anoikis resistance, and transformation of immortalized human bronchial epithelial cells via Erk activation-dependent suppression of E-cadherin

, 2017
Xin Yao, Selena Gray, Tri Pham, Mychael Delgardo, An H. Nguyen, Stephen Do, Shubha Kale Ireland, Renwei Chen, Asim B. Abdel‐Mageed, Hector Biliran   +9 more
openalex   +2 more sources

Mapping transmembrane binding partners for E-cadherin ectodomains

, 2020
Omer Shafraz, Bin Xie, Soichiro Yamada, Sanjeevi Sivasankar   +3 more
openalex   +2 more sources

Antibody‐Empowered Nanomedicine for Precise Biomedical Applications

Advanced Science, EarlyView.
This review explores strategies for functionalizing nanoparticles with antibodies to construct antibody‐empowered nanomedicine. It discusses the classification of these nanomedicines based on antibody structure, with a specific focus on their biomedical applications in diagnostics, bioimaging, and therapeutics for various diseases.
Chen Chen, Xinglin Chen, Zhenhao Gao, Meng Sun, Yaozong Yu, Fang Lv, Qiujun Wang, Jinfeng Zhang   +7 more
wiley   +1 more source

N-cadherin mechanosensing in ovarian follicles controls oocyte maturation and ovulation. [PDF]

Elife
Emery A, Blaschuk OW, Dinh DT, McPhee T, Becker R, Abell AD, Mrozik KM, Zannettino ACW, Robker RL, Russell DL.   +9 more
europepmc   +1 more source

Compensatory Interplay Between Clarin‐1 and Clarin‐2 Deafness‐Associated Proteins Governs Phenotypic Variability in Hearing

Advanced Science, EarlyView.
Functional compensation between clarin‐1 and clarin‐2 in cochlear hair cells. Hearing loss associated with CLRN1 mutations shows striking phenotypic variability; however, the underlying mechanisms remain poorly understood. This study reveals that clarin‐1 and clarin‐2 function cooperatively in cochlear hair cells to sustain mechanoelectrical ...
Maureen Wentling, Aïda Yakhlef Sanchez, Nicolas Thelen, Müge Senarisoy, Maria Hogg, Steven Condamine, Andrea Lelli, Emilia Wysocka, Pranav Patni, Sandrine Vitry, Kerem Yasin Yildizhan, Sébastien Le Gal, Sylvie Nouaille, Michael R. Bowl, Marc Thiry, Didier Dulon, Sedigheh Delmaghani, Aziz El‐Amraoui   +17 more
wiley   +1 more source

α-catenin phosphorylation is elevated during mitosis to resist apical rounding and epithelial barrier leak

Biology Open
Phuong M. Le, Jeanne M. Quinn, Annette S. Flozak, Adam W. T. Steffeck, Che-Fan Huang, Cara J. Gottardi   +5 more
doaj   +1 more source