Results 91 to 100 of about 818 (145)

Immune responses and protection induced by CAF01 in a TB model.

, 2013
C57BL/6 mice were immunized three times with 2 µg of Ag85B-ESAT-6 in CAF01 or Al(OH)3. A) Three weeks after the last immunization, mice were bled by periorbital puncture and individual sera tested for Ag85B-ESAT-6 IgG1, B) IgG2b or C) IgG2c by ELISA (n = 
Kerstin Werninghaus (104676), Roland Lang (77155), Jon Hansen (16978), Michael Theisen (81720), Claus Aagaard (263500), Dennis Christensen (104693), Else Marie Agger (104700), Brian S. Vandahl (376819), Peter Andersen (88335), Frank Follmann (248464), Ida Rosenkrands (299547), Carsten Kirschning (104698), Karima Brahimi (376818)   +12 more
core   +1 more source

Controlled human malaria infection to evaluate the efficacy of the asexual blood-stage malaria vaccine candidate GMZ2- CAF01 [PDF]

Malaria is a life-threatening protozoan parasite disease transmitted by mosquitoes, which infected approximately 228 million people worldwide in 2018, of which 405,000 people died.
Engelhorn, Julie
core   +1 more source

Phosphatidylinositolmannoside vaccination induces lipid-specific Th1-responses and partially protects guinea pigs from Mycobacterium tuberculosis challenge. [PDF]

Sci Rep, 2023
Eckhardt E, Schinköthe J, Gischke M, Sehl-Ewert J, Corleis B, Dorhoi A, Teifke J, Albrecht D, Geluk A, Gilleron M, Bastian M.   +10 more
europepmc   +1 more source

Head-to-Head Comparison of Novel Vaccine Technologies Comes with a Minefield of Challenges. [PDF]

Pharmaceutics, 2023
Christensen D.
europepmc   +1 more source

Nanoparticle based drug delivery systems improve antimalarial efficacy and vaccine performance in African research and clinical settings. [PDF]

Discov Nano
Dangana RS, Ebhohimen IE, Otele IM, Idiakheua OD, Okpeku M.   +4 more
europepmc   +1 more source

Editorial: Innovative adjuvant strategies: enhancing vaccine efficacy through transdisciplinary approaches. [PDF]

Front Immunol
Angulo C, Parola AD, Ramos Vega AA.
europepmc   +1 more source

Parenteral neonatal priming followed by heterologous mucosal booster favors IgM⁺ memory B cell induction over systemic plasma cell differentiation. [PDF]

Front Immunol
Foroutan Pajoohian P, Aradottir Pind AA, Molina Estupiñan JL, Christensen D, Pedersen GK, Olafsdottir TA, Jonsdottir I, Bjarnarson SP.   +7 more
europepmc   +1 more source

A protective, single-visit TB vaccination regimen by co-administration of a subunit vaccine with BCG. [PDF]

NPJ Vaccines, 2023
Dijkman K, Lindenstrøm T, Rosenkrands I, Søe R, Woodworth JS, Lindestam Arlehamn CS, Mortensen R.   +6 more
europepmc   +1 more source

IL-4 and helminth infection downregulate MINCLE-dependent macrophage response to mycobacteria and Th17 adjuvanticity. [PDF]

Elife, 2023
Schick J, Altunay M, Lacorcia M, Marschner N, Westermann S, Schluckebier J, Schubart C, Bodendorfer B, Christensen D, Alexander C, Wirtz S, Voehringer D, da Costa CP, Lang R.   +13 more
europepmc   +1 more source

Expression of CD103 facilitates localization and activation of CD4⁺ T cells within Mycobacterium tuberculosis lung-lesions. [PDF]

Mucosal Immunol
Lindenstrøm T, Panagiotopoulou N, Cohen SB, Rodriguez PT, Woodworth JS, Morikawa M, Halima M, Maymann CM, Hu T, Stull SM, Woetmann A, Andersen PL, Urdahl KB, Gern BH, Mortensen R.   +14 more
europepmc   +1 more source