Results 131 to 140 of about 3,141 (147)

Anti-activin treatment increases T cell infiltration in breast and pancreatic tumours and promotes survival in a SMAD4-null mouse pancreatic cancer model

open access: yes
McCluney S   +17 more
europepmc   +1 more source

Decoding inflammatory regulation in ovarian cancer at single-cell resolution. [PDF]

open access: yesFront Immunol
Yu J   +6 more
europepmc   +1 more source

Synthesis, physical characteristics, and biocompatibility test of chitosan-alginate-fucoidan scaffold as an alternative material for alveolar bone substitution. [PDF]

open access: yesBMC Oral Health
Hamrun N   +10 more
europepmc   +1 more source

Localized 2'-OH Acylation at Poly(A) Extends RNA Translation. [PDF]

open access: yesJ Am Chem Soc
Fang L   +6 more
europepmc   +1 more source

Breast cancer cell migration is potentiated by associated fibroblasts through a laminin-511-driven cortical localization of Arp2/3

open access: yes
Banerjee M   +8 more
europepmc   +1 more source
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Tuneable hydrogels of Caf1 protein fibers

Materials Science and Engineering: C, 2018
Capsular antigen fraction 1 (Caf1) is a robust polymeric protein forming a protective layer around the bacterium Yersinia pestis. Occurring as ≈1 μm polymeric fibers, it shares its immunoglobulin-like fold with the majority of mammalian extracellular proteins such as fibronectin and this structural similarity suggests that this unusual polymer could ...
Gema Dura   +4 more
openaire   +3 more sources

Conformational states and association mechanism of Yersinia pestis Caf1 subunits

Biochemical and Biophysical Research Communications, 2008
Bacterial infectivity often relies on efficient attachment to the host cells through adhesive extensions. Unveiling the structural basis of the formation of these organelles is of paramount importance for both academic and applicative implications.
Vitagliano Luigi   +3 more
openaire   +7 more sources

The N-terminus modulates human Caf1 activity, structural stability and aggregation

International Journal of Biological Macromolecules, 2012
Caf1 is a deadenylase component of the CCR4-Not complex. Here we found that the removal of the N-terminus resulted in a 30% decrease in human Caf1 (hCaf1) activity, but had no significant influence on main domain structure. The removal of the N-terminus led to a decrease in the thermal stability, while the existence of the N-terminus promoted hCaf1 ...
Li-Kui, Feng, Yong-Bin, Yan
openaire   +2 more sources

Caf1 regulates Ash1 histone methyltransferase activity via sensing unmodified histone H3

2023
AbstractHistone modifications are one of key mechanisms to regulate gene expression. Ash1 is a histone H3K36 methyltransferase and involved in gene activation. Ash1 forms a large complex with Mrg15 and Caf1/p55/Nurf55/RbAp48 (AMC complex). Ash1 subunit alone has very low activity due to the auto-inhibition and the binding of Mrg15 releases the auto ...
Eojin Yoon, Ji-Joon Song
openaire   +1 more source

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