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Bee Propolis (Caffeic Acid Phenethyl Ester) Against Cancer

2021
Caffeic acid phenethyl ester (CAPE) is the vital natural phenolic chemical composite present in a variety of plants which is also abundantly present in the honeybee hives as propolis. It is the combination of caffeic acid and phenethyl alcohol. There are many studies reported the pharmacological and physiological activities of CAPE in a variety of in ...
Maqsood Ur Rehman   +3 more
openaire   +1 more source

Microencapsulation of caffeic acid phenethyl ester and caffeic acid phenethyl amide by inclusion in hydroxypropyl-β-cyclodextrin

Food Chemistry, 2018
Caffeic acid phenethyl ester (CAPE) is a bioactive polyphenolic compound obtained from propolis extract. Although it has a broad therapeutic potential, the bioavailability of CAPE is limited, due to reduced solubility and poor plasmatic stability. Efforts to reduce these pharmacokinetic drawbacks resulted in the synthesis of caffeic acid phenethyl ...
E. Manuela P.J. Garrido   +5 more
openaire   +2 more sources

Effects of Caffeic Acid Phenethyl Ester on Pancreatitis in Rats

Journal of Surgical Research, 2008
This study investigated the effect of caffeic acid phenethyl ester (CAPE) on acute necrotizing pancreatitis (ANP) induced by glycodeoxycholic acid in rats. CAPE, an active component of honeybee propolis, has previously been determined to have antioxidant, anti-inflammatory, antiviral, and anticancer activities.Forty-eight rats were divided into four ...
ERDOĞAN, SELİM   +7 more
openaire   +3 more sources

Caffeic Acid Phenethyl Ester (CAPE)

Shock, 2014
Excessive free radical production by immune cells has been linked to cell death and tissue injury during sepsis. Peroxynitrite is a short-lived oxidant and a potent inducer of cell death that has been identified in several pathological conditions. Caffeic acid phenethyl ester (CAPE) is an active component of honeybee products and exhibits antioxidant ...
Mustafa, Kassim   +9 more
openaire   +2 more sources

Yeast Metabolic Engineering for Biosynthesis of Caffeic Acid-Derived Phenethyl Ester and Phenethyl Amide

ACS Synthetic Biology, 2023
Caffeic acid (CA)-derived phenethyl ester (CAPE) and phenethyl amide (CAPA) are extensively investigated bioactive compounds with therapeutic applications such as antioxidant, anti-inflammatory, and anticarcinogenic properties. To construct microbial cell factories for production of CAPE or CAPA is a promising option given the limitation of natural ...
Zi-Chen Jia   +6 more
openaire   +2 more sources

The effect of caffeic acid phenethyl ester (CAPE) on tympanosclerosis

International Journal of Pediatric Otorhinolaryngology, 2017
To investigate the effects of caffeic acid phenethyl ester (CAPE) on tympanosclerosis.Thirty-two male Sprague Dawley rats were separated into 4 groups as CAPE (n = 10), alcohol (n = 10), control (n = 8) and normal (n = 4) groups. All tympanic membranes except normal group were myringotomised and type 3 Streptococcus pneumoniae strains was injected into
İbrahim, Ağrı   +8 more
openaire   +2 more sources

Caffeic acid phenethyl ester ameliorates cadmium-induced kidney mitochondrial injury

Chemico-Biological Interactions, 2012
This study examined whether caffeic acid phenethyl ester (CAPE) can protect kidney mitochondria against cadmium toxicity. Kidney mitochondria isolated from Wistar rat were exposed to cadmium and/or CAPE at various concentrations. Mitochondrial function, ultrastructure and oxidative stress status were determined.
Anongporn, Kobroob   +2 more
openaire   +2 more sources

Therapeutic Potential of Caffeic Acid Phenethyl Ester (CAPE) in Diabetes

Current Medicinal Chemistry, 2019
Diabetes mellitus is a complex metabolic disease characterized by high blood sugar levels. Different pathogenic processes are involved in the etiology of the disease. Indeed, chronic diabetes hyperglycemia is often associated with severe long-term complications including cardiovascular symptoms, retinopathy, nephropathy, and neuropathy.
PITTALA', Valeria   +5 more
openaire   +2 more sources

Caffeic acid phenethyl ester prevents intestinal reperfusion injury in rats

Journal of Pediatric Surgery, 1999
Ischemia-reperfusion injury is encountered frequently in conditions that diminish intestinal blood flow. Caffeic acid phenethyl ester (CAPE), which is a specific component of the honeybee hive product propolis, exhibits potential antioxidant properties.
U, Koltuksuz   +8 more
openaire   +2 more sources

Effects of Caffeic Acid Phenethyl Ester (CAPE) on Hepatopulmonary Syndrome

Inflammation, 2010
The aim of this study was to investigate the effects of caffeic acid phenethyl ester (CAPE) on inflammatory and related histopathological changes in the lung and liver in experimental hepatopulmonary syndrome (HPS) model. Forty Sprague Dawley rats were used in this study. The animals were divided into four groups of ten rats each.
Ahmet, Tekin   +8 more
openaire   +2 more sources

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