Exploring the anti-biofilm activity of cinnamic acid derivatives in Candida albicans [PDF]
, 2016 Some compounds, characterized by phenylethenyl moiety, such as methyl cinnamate and caffeic acid phenethyl ester, are able to inhibit C. albicans biofilm formation.
Costi, Roberta +6 more
core +1 more source
Caffeic acid phenethyl ester is protective in experimental ulcerative colitis via reduction in levels of pro-inflammatory mediators and enhancement of epithelial barrier function [PDF]
, 2018 BACKGROUND: Inhibition of the nuclear factor kappa beta (NF-κβ) pathway has been proposed as a therapeutic target due to its key role in the expression of pro-inflammatory genes, including pro-inflammatory cytokines, chemokines, and adhesion molecules ...
Khan, MN +3 more
core +4 more sources
Caffeic acid phenethyl amide ameliorates ischemia/reperfusion injury and cardiac dysfunction in streptozotocin-induced diabetic rats [PDF]
, 2014 BACKGROUND: Caffeic acid phenethyl ester (CAPE) has been shown to protect the heart against ischemia/reperfusion (I/R) injury by various mechanisms including its antioxidant effect. In this study, we evaluated the protective effects of a CAPE analog with
An-Sheng Lee +7 more
core +1 more source
Antioxidant properties of hydroxycinnamic acids: a review of structure- activity relationships [PDF]
, 2013 Hydroxycinnamic acids (HCAs) are important phytochemicals possessing significant biological properties. Several investigators have studied in vitro antioxidant activity of HCAs in detail.
Borges, Fernanda +4 more
core +1 more source
Molecules, 2017 Glioblastoma multiforme (GBM) is an aggressive brain tumor that correlates with short patient survival and for which therapeutic options are limited. Polyphenolic compounds, including caffeic acid phenethyl ester (CAPE, 1a), have been investigated for ...
Pier Morin +6 more
doaj +1 more source
Study of CAPE effect on apoptosis induction in AGS human gastric cancer cell line [PDF]
, 2016 Background: Propolis is a natural product of bee and caffeic acid phenethyl ester (CAPE) is a pharmacologically important product of propolis. Objectives: The aim of this study was to investigate the effect of CAPE on apoptosis induction in AGS human ...
Chen YJ +14 more
core +1 more source
Antioxidant effect of caffeic acid phenethyl ester in experimentally induced periodontitis
Clinical Oral Investigations, 2021 The aim of the present study was to evaluate the antioxidant effect of systemically administered caffeic acid phenethyl ester (CAPE) in periodontitis.Forty rats were randomly divided into four groups: control, lipopolysaccharide-induced experimental periodontitis (LPS), CAPE 5: LPS+5 μmol/kg/day CAPE, and CAPE 10: LPS+10 μmol/kg/day CAPE.
Feyza Otan Özden +3 more
openaire +5 more sources
Regulatory Effects of Caffeic Acid Phenethyl Ester on Neuroinflammation in Microglial Cells [PDF]
International Journal of Molecular Sciences, 2015 Microglial activation has been widely demonstrated to mediate inflammatory processes that are crucial in several neurodegenerative disorders. Pharmaceuticals that can deliver direct inhibitory effects on microglia are therefore considered as a potential strategy to counter balance neurodegenerative progression.
Cheng-Fang Tsai +9 more
openaire +3 more sources
Mediators of Inflammation, 2017 Leukotrienes are inflammatory mediators that actively participate in the inflammatory response and host defense against pathogens. However, leukotrienes also participate in chronic inflammatory diseases. 5-lipoxygenase is a key enzyme in the biosynthesis
Luc H. Boudreau +6 more
doaj +1 more source
Propolis: A complex natural product with a plethora of biological activities that can be explored for drug development [PDF]
, 2015 The health industry has always used natural products as a rich, promising, and alternative source of drugs that are used in the health system. Propolis, a natural resinous product known for centuries, is a complex product obtained by honey bees from ...
Almeida Aguiar, Cristina +2 more
core +3 more sources