Simple Summary Cancer therapy suffers from its high cost and high rate of adverse effects and relapse of the disease. Hence, the new (preferably natural), economic and safer therapeutic as well preventive measures have been on demand and have been ...
A. N. Sari+10 more
semanticscholar +1 more source
Effect of Propolis on moderate persistent asthma: A phase two randomized, double blind, controlled clinical trial [PDF]
Objective: The aims of this study was to determine the effect of Propolis (resinous mixture that honey bees produce by mixing saliva and beeswax) on clinical and physiological findings of moderate persistent asthma.
Majid Mirsadraee+4 more
doaj +1 more source
THE INHIBITORY EFFECT OF PROPOLIS AND CAFFEIC ACID PHENETHYLESTER ON CYCLOOXYGENASE ACTIVITY IN J774 MACROPHAGES. [PDF]
The effect of an ethanolic extract of propolis, with and without CAPE, and some of its components on cyclooxygenase (COX-1 and COX-2) activity in J774 macrophages has been investigated.
BORRELLI, FRANCESCA+5 more
core +1 more source
The recent novel coronavirus, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2/2019-nCoV) has caused a large number of deaths around the globe. There is an urgent need to understand this new virus and develop prophylactic and therapeutic drugs.
Vipul Kumar+4 more
semanticscholar +1 more source
In the present study, it is aimed to evaluate the effects of caffeic acid phenethyl ester (CAPE) against acute paw inflammation induced by carragenan (Carr) at macro and micro levels.
H. S. semis+4 more
semanticscholar +1 more source
Activity of Caffeic Acid Phenethyl Ester in Caenorhabditis Elegans [PDF]
Caffeic acid (3,4-dihydroxycinnamic acid) phenethyl ester (CAPE), the major constituent of propolis, is able to increase the survival of the nematode Caenorhabditis elegans after infection with the fungal pathogen Candida albicans.CAPE increases the expression of several antimicrobial proteins involved in the immune response to C. albicans.
Julia Munro+11 more
openaire +2 more sources
Caffeic Acid Derivatives Inhibit the Growth of Colon Cancer: Involvement of the PI3-K/Akt and AMPK Signaling Pathways [PDF]
The aberrant regulation of phosphatidylinositide 3-kinases (PI3-K)/Akt, AMP-activated protein kinase (AMPK) and mammalian target of rapamycin (m-TOR) signaling pathways in cancer has prompted significant interest in the suppression of these pathways to ...
Chiang, En-Pei Isabel+6 more
core +2 more sources
Exploring the anti-biofilm activity of cinnamic acid derivatives in Candida albicans [PDF]
Some compounds, characterized by phenylethenyl moiety, such as methyl cinnamate and caffeic acid phenethyl ester, are able to inhibit C. albicans biofilm formation.
Costi, Roberta+6 more
core +1 more source
Caffeic acid phenethyl ester is protective in experimental ulcerative colitis via reduction in levels of pro-inflammatory mediators and enhancement of epithelial barrier function [PDF]
BACKGROUND: Inhibition of the nuclear factor kappa beta (NF-κβ) pathway has been proposed as a therapeutic target due to its key role in the expression of pro-inflammatory genes, including pro-inflammatory cytokines, chemokines, and adhesion molecules ...
Khan, MN+3 more
core +4 more sources
Antioxidant properties of hydroxycinnamic acids: a review of structure- activity relationships [PDF]
Hydroxycinnamic acids (HCAs) are important phytochemicals possessing significant biological properties. Several investigators have studied in vitro antioxidant activity of HCAs in detail.
Borges, Fernanda+4 more
core +1 more source