Results 41 to 50 of about 4,210 (197)

Caffeic Acid Phenethyl Ester (CAPE) in Romanian Propolis

open access: yesBulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca. Animal Science and Biotechnologies, 2014
Introduction. Propolis is an important bee product, rich in biologically active compounds (MAƒrghitaș et al ., 2013). It is collected by the bees  from buds and exudates of different trees and plants and it has been used since ancient times as a natural remedy or in embalming process.
Otilia Bobis   +3 more
openaire   +3 more sources

“Molecular Docking and Dynamic Studies of Amide Derivatives from Cinnamic Acid with Potential Anti‐Dengue Virus Activity”

open access: yesChemistryOpen, EarlyView.
A library of easily synthesizable CAPE analogs was screened in silico against the dengue virus envelope protein. Compound LQM778 showed stable binding and promising inhibitory potential. This study highlights LQM778 as a candidate for future in vitro validation and structural optimization toward accessible antiviral agents against dengue.
Luis Alfonso Cárdenas‐Granados   +9 more
wiley   +1 more source

Anti-colon cancer effect of caffeic acid p-nitro-phenethyl ester in vitro and in vivo and detection of its metabolites

open access: yesScientific Reports, 2017
Caffeic acid phenethyl ester (CAPE), extracted from propolis, was proven to inhibit colon cancer. Caffeic acid p-nitro-phenethyl ester (CAPE-pNO2), a derivative of CAPE, was determined to be an anti-platelet agent and a protector of myocardial ischaemia ...
Hao Tang   +5 more
doaj   +1 more source

Composition of Brazilian and Chinese Propolis for Patch Testing

open access: yesContact Dermatitis, Volume 93, Issue 1, Page 56-60, July 2025.
The compositions of Brazilian propolis and 2 samples of Chinese propolis used for patch testing were analysed with gas chromatography–mass spectrometry/flame ionisation detection (GC–MS/FID) of volatile components obtained by headspace SPME (solid phase microextraction). The ingredients of Brazilian and Chinese propolis were quite different.
Evelyn Calta   +4 more
wiley   +1 more source

Organ toxicities associated with diet‐induced obesity in rats: Investigation of changes in activities selected enzymes

open access: yesBiotechnology and Applied Biochemistry, Volume 72, Issue 3, Page 743-754, June 2025.
Abstract Obesity stands out as one of the most significant health problems in the modern world. The prevalence of high‐calorie diets (HCDs) globally exacerbates this condition. Throughout history, plants and plant‐derived food products have been utilized for medicinal purposes, demonstrating their efficacy in the treatment and prevention of various ...
Bedia Bati
wiley   +1 more source

Value of Caffeic Acid Phenethyl Ester Pretreatment in Experimental Sepsis Model in Rats [PDF]

open access: yesMediators of Inflammation, 2015
Background and Aim. The aim of this study was to determine the actions of caffeic acid phenethyl ester (CAPE) on the changes of endothelin‐1 (ET‐1) level, tumor necrosis factor‐ (TNF‐) alpha, and oxidative stress parameters such as superoxide dismutase (SOD) activities and malondialdehyde (MDA) levels in experimental sepsis model in rats. Materials and
Cemile Koca   +10 more
openaire   +4 more sources

Novel Oxadiazole‐Based Bioisostere of Caffeic Acid Phenethyl Ester: Synthesis, Anticancer Activity, and Inhibition of Lipoxygenase Product Biosynthesis

open access: yesDrug Development Research, Volume 86, Issue 3, May 2025.
ABSTRACT Caffeic acid phenethyl ester (1), a honeybee propolis component, possesses many bioactive properties, making it a useful scaffold for drug research. Further, CAPE (1) is a more effective inhibitor of the biosynthesis of 5‐lipoxygenase (5‐LO) products compared to Zileuton, the only clinically‐approved direct 5‐LO inhibitor.
Mika A. Robichaud   +5 more
wiley   +1 more source

Caffeic acid phenethyl ester inhibits liver fibrosis in rats

open access: yesWorld Journal of Gastroenterology, 2015
To investigate the hepatoprotective effects and antioxidant activity of caffeic acid phenethyl ester (CAPE) in rats with liver fibrosis.A total of 75 male Sprague-Dawley rats were randomly assigned to seven experimental groups: a normal group (n = 10), a vehicle group (n = 10), a model group (n = 15), a vitamin E group (n = 10), and three CAPE groups ...
Ning Yang   +6 more
openaire   +3 more sources

Harnessing Jasminum Bioactive Compounds: Updated Insights for Therapeutic and Food Preservation Innovations

open access: yesFood Frontiers, Volume 6, Issue 3, Page 1093-1128, May 2025.
Jasminum bioactives improve food preservation by providing antimicrobial and antioxidant effects, especially when incorporated into active packaging, edible films, and nanoformulations that enhance stability and controlled release. They also offer many pharmacological benefits, including anti‐inflammatory, neuroprotective, and wound‐healing properties.
Antonio Rescigno   +17 more
wiley   +1 more source

Water-Mediated Synthesis of (E)-3-(1-Methyl-1H-benzo[d]imidazol-5-yl)-N-phenethylacrylamide, a Caffeic Acid Phenethyl Amide Analogue

open access: yesMolbank
Caffeic acid phenethyl ester (CAPE) is a phenolic natural product with diverse biological activities, notably anticancer properties. However, its ester group is metabolically unstable.
Muppidi Subbarao, Sean M. Kerwin
doaj   +1 more source

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