Results 61 to 70 of about 12,490 (282)

Caffeic acid phenethyl amide ameliorates ischemia/reperfusion injury and cardiac dysfunction in streptozotocin-induced diabetic rats [PDF]

, 2014
BACKGROUND: Caffeic acid phenethyl ester (CAPE) has been shown to protect the heart against ischemia/reperfusion (I/R) injury by various mechanisms including its antioxidant effect. In this study, we evaluated the protective effects of a CAPE analog with
An-Sheng Lee, Hsi-Lin Chiu, Ming-Jai Su, Wei-Lung Chang, Wen-Pin Chen, Yi-Jin Ho, Ying-Kang Tsai, Yueh-Hsiung Kuo   +7 more
core   +1 more source

Substituted Caffeic and Ferulic Acid Phenethyl Esters: Synthesis, Leukotrienes Biosynthesis Inhibition, and Cytotoxic Activity

Molecules, 2017
Glioblastoma multiforme (GBM) is an aggressive brain tumor that correlates with short patient survival and for which therapeutic options are limited. Polyphenolic compounds, including caffeic acid phenethyl ester (CAPE, 1a), have been investigated for ...
Pier Morin, Patrick-Denis St-Coeur, Jérémie A. Doiron, Marc Cormier, Julie J. Poitras, Marc E. Surette, Mohamed Touaibia   +6 more
doaj   +1 more source

Exploring the anti-biofilm activity of cinnamic acid derivatives in Candida albicans [PDF]

, 2016
Some compounds, characterized by phenylethenyl moiety, such as methyl cinnamate and caffeic acid phenethyl ester, are able to inhibit C. albicans biofilm formation.
Costi, Roberta, D'Auria, Felicia Diodata, DE VITA, Daniela, DI SANTO, Roberto, Pandolfi, Fabiana, Scipione, Luigi, Simonetti, Giovanna   +6 more
core   +1 more source

Antitumoral and antiangiogenic activity of Portuguese propolis in in vitro and in vivo models [PDF]

, 2014
Propolis, a natural product, has important biological properties, however, studies with Portuguese propolis are scarce. Thus, we aimed to characterize the chemical composition and the antitumoural and antiangiogenic activities of a sample from Pereiro ...
Abílio J.F.N. Sobral, Ahn, Amoros, Ana Margarida Ferreira, Bankova, Bankova, Bankova, Bankova, Bankova, Bankova, Barlak, Cardoso, Chan, Chuu, Cristina Almeida-Aguiar, Daleprane, Falcão, Falcão, Fokt, Fátima Baltazar, Gekker, Gomez-Caravaca, Gordaliza, He, Hu, Hwang, Ishihara, Izuta, Kai, Kunimasa, Kuo, Lee, Li, Lofty, Luo, Manach, Martinho, Mavri, Miguel, Miranda-Goncalves, Moreira, Newman, Ordonez, Orsolic, Park, Pellati, Popova, Pratsinis, Ricardo Silva-Carvalho, Scazzocchio, Sforcin, Silva, Singleton, Sulaiman, Susana M. Cardoso, Szliszka, Szliszka, Szliszka, Tolba, Ueda, Umthong, Valente, Valença, Vera Miranda-Gonçalves, Viuda-Martos, Watanabe, Woisky, Wu, Xuan   +68 more
core   +1 more source

Caffeic acid phenethyl ester (CAPE): pharmacodynamics and potential for therapeutic application [PDF]

Pharmacia, 2019
Caffeic acid phenethyl ester (CAPE) is the major pharmacologically-active component of some propolis types, rich in polyphenols, such as poplar propolis types.
Yordan Yordanov
doaj   +3 more sources

Caffeic Acid Phenethyl Ester Inhibits Endothelial Tissue Factor Expression

Biological and Pharmaceutical Bulletin, 2013
Caffeic acid phenethyl ester (CAPE) is a component of honeybee hives with various beneficial properties. Tissue factor (TF), the key trigger of thrombosis, is expressed in human endothelial cells. This study was designed to investigate whether CAPE modulates TF expression in human aortic endothelial cells (HAECs). Western blots and real-time polymerase
Cathérine, Gebhard, Barbara Elisabeth, Stähli, Stephanie, Largiadèr, Erik Walter, Holy, Alexander, Akhmedov, Giovanni Guido, Camici, Thomas Felix, Lüscher, Felix Christoph, Tanner   +7 more
openaire   +3 more sources

Caffeic acid phenethyl ester prevents neonatal hypoxic-ischaemic brain injury [PDF]

Brain, 2004
Neonatal hypoxic-ischaemic (HI) brain injury resulting in encephalopathy is a leading cause of morbidity and mortality with no effective treatment. Here we show that caffeic acid phenethyl ester (CAPE), an active component of propolis, administered either before or after an HI insult, significantly prevents HI-induced neonatal rat brain damage in the ...
Xing, Wei, Liming, Zhao, Zhizhong, Ma, David M, Holtzman, Chong, Yan, Richard C, Dodel, Harald, Hampel, Wolfgang, Oertel, Martin R, Farlow, Yansheng, Du   +9 more
openaire   +2 more sources

New Hydroxycinnamic Acid Esters as Novel 5-Lipoxygenase Inhibitors That Affect Leukotriene Biosynthesis

Mediators of Inflammation, 2017
Leukotrienes are inflammatory mediators that actively participate in the inflammatory response and host defense against pathogens. However, leukotrienes also participate in chronic inflammatory diseases. 5-lipoxygenase is a key enzyme in the biosynthesis
Luc H. Boudreau, Grégoire Lassalle-Claux, Marc Cormier, Sébastien Blanchard, Marco S. Doucet, Marc E. Surette, Mohamed Touaibia   +6 more
doaj   +1 more source

Standardization, anti-carcinogenic potential and biosafety of Indian propolis

Journal of Ayurveda and Integrative Medicine, 2019
Background: Propolis from apiculture is known for wide range of medicinal properties owing to its vast chemical constituents including polyphenols, flavonoids and anticancer agent Caffeic acid phenethyl ester (CAPE).
Harshad Kapare, Sathiyanarayanan Lohidasan, Arulmozhi Sinnathambi, Kakasaheb Mahadik   +3 more
doaj   +1 more source

Study of CAPE effect on apoptosis induction in AGS human gastric cancer cell line [PDF]

, 2016
Background: Propolis is a natural product of bee and caffeic acid phenethyl ester (CAPE) is a pharmacologically important product of propolis. Objectives: The aim of this study was to investigate the effect of CAPE on apoptosis induction in AGS human ...
Chen YJ, Frenkel K, Frenkel K, Gordaliza M, Grunberger D, Huang MT, Koltuksuz U, Michaluart P, Nikokar M, Nomura M, Roder DM, Sasaki N, Shirzad H, Son S, Wang HL   +14 more
core   +1 more source