Caffeic acid phenethyl ester promotes haematopoietic stem/progenitor cell homing and engraftment
Background Several studies have suggested that caffeic acid phenethyl ester (CAPE) can induce the expression of hypoxia inducible factor-1α (HIF-1α) protein.
Xiaofang Chen+12 more
doaj +1 more source
Caffeic acid phenethyl ester (CAPE): cornerstone pharmacological studies and drug delivery systems [PDF]
Propolis is a natural product with a plethora of biological effects, utilized by traditional medicine since antiquity. However, its application as a pharmaceutical is hindered by its variable composition and difficult standardization. CAPE has been shown
Yordan Yordanov
doaj +3 more sources
Synthetic evolution of Saccharomyces cerevisiae for biomanufacturing: Approaches and applications
Abstract The yeast Saccharomyces cerevisiae is a well‐studied unicellular eukaryote with a significant role in the biomanufacturing of natural products, biofuels, and bulk and value‐added chemicals, as well as the principal model eukaryotic organism utilized for fundamental research.
Zhen Wang+5 more
wiley +1 more source
Morphological changes of apoptosis and cytotoxic effects induced by Caffeic acid phenethyl ester in AGS human gastric cancer cell line [PDF]
Introduction: Gastric cancer is the fourth prevalent cancer and the second reason for cancer-associated mortalities worldwide. Caffeic acid phenethyl ester (CAPE) is one of the main medicinal components of propolis.
Amini-Sarteshnizi, Nematallah.+4 more
core
Exploiting members of the BAHD acyltransferase family to synthesize multiple hydroxycinnamate and benzoate conjugates in yeast [PDF]
BACKGROUND: BAHD acyltransferases, named after the first four biochemically characterized enzymes of the group, are plant-specific enzymes that catalyze the transfer of coenzyme A-activated donors onto various acceptor molecules. They are responsible for
A Del Olmo+88 more
core +2 more sources
Sirtuin 1 (Sirt1), a key NAD+‐dependent deacetylase, has become a leading therapeutic target for spinal cord injury (SCI) repair due to its regulation of multiple pathological processes, including inflammation, oxidative stress, and cell death. Sirt1 not only protects and regenerates neurons but also modulates astrocytes, microglia, oligodendrocytes ...
Jinze Li+5 more
wiley +1 more source
Evaluation of the In vitro cytotoxic activity of caffeic acid derivatives and liposomal formulation against pancreatic cancer cell lines [PDF]
Pancreatic cancer belongs to the most aggressive group of cancers, with very poor prognosis. Therefore, there is an important need to find more potent drugs that could deliver an improved therapeutic approach.
Cybulski, Marcin+5 more
core +1 more source
Progress in Research on Regulated Cell Death in Cerebral Ischaemic Injury After Cardiac Arrest
ABSTRACT Ischaemic damage to the brain is the main cause of brain injury after cardiac arrest. The current treatment focuses on early reperfusion, but reperfusion tends to cause reperfusion injury, which is a significant problem. Cell death is an irreversible and normal end to cell life, playing key roles in maintaining the homeostasis and development ...
Zumin Chen+5 more
wiley +1 more source
Effects of Caffeic Acid Phenethyl Ester on Anastomotic Healing in Secondary Peritonitis
We aimed to investigate the effects of caffeic acid phenethyl ester (CAPE) on wound healing in left colonic anastomoses in the presence of intraperitoneal sepsis induced by cecal ligation and puncture (CLP) in a rodent model.This experimental study was conducted on 48 male Wistar albino rats.
Teke, Z.+7 more
openaire +7 more sources
Biotransformation of caffeoyl quinic acids from green coffee extracts by Lactobacillus johnsonii NCC 533 [PDF]
Acknowledgements The authors are grateful to Nicole Page-Zoerkler and Olivier Mauroux for their technical assistant. We thank David Pridmore and Kimo Makkinen for critical reading of this manuscript.Peer reviewedPublisher ...
Bel-Rhlid, Rachid+4 more
core +2 more sources