Results 81 to 90 of about 8,207 (238)

Propolis suppresses atopic dermatitis through targeting the MKK4 pathway

BioFactors, Volume 51, Issue 1, January/February 2025.
This study demonstrates that propolis exhibits anti‐inflammatory, skin barrier‐enhancing, and antipruritic effects in cell, human skin, and mouse models. These effects are mediated by targeting MKK4 in the p38 signaling pathway and are achieved through the active compound, caffeic acid phenethyl ester (CAPE).
Ye‐Ryeong Cho, Eui Jeong Han, Eun Heo, Arachchige Maheshika Kumari Jayasinghe, Jihyun Won, Soohwan Lee, Taegun Kim, Sung‐Kuk Kim, Seokwon Lim, Soon Ok Woo, Gyoonhee Han, Wonku Kang, Ginnae Ahn, Sanguine Byun   +13 more
wiley   +1 more source

Evaluation of the effect of Chrysin and Caffeic acid phenethyl ester on eIF4E expression in AGS cell line [PDF]

, 2014
Introduction: The Ras/Akt/mTORC1 signal transduction pathways play a critical role in regulating translation and converge on initiation factor eukaryotic translation initiation factor 4E (eIF4E) which is overexpressed in various malignancies.
Abolhasani, Marziyeh., Amini Sarteshnizi, Neamatollah., Doosti, Abbas., Gholami-Arjenaki, Mostafa., Hashemzadeh-Chaleshtori, Morteza., Teimori, Hossein.   +5 more
core  

Functional Hydrogels for the Treatment of Periodontitis

Biosurface and Biotribology, Volume 11, Issue 1, January/December 2025.
ABSTRACT Periodontitis is a common and serious oral health problem. It not only damages the health of periodontal tissues but also has potential impacts on the whole body. Existing treatment methods, such as mechanical debridement and antibiotic treatment, have obvious limitations.
Yongjie Luo, Lu Yang, Chubao Liu, Liwei Yan, Chaoming Xie   +4 more
wiley   +1 more source

Antiviral Properties of Caffeic Acid Phenethyl Ester and Its Potential Application

Journal of Intercultural Ethnopharmacology, 2015
Caffeic acid phenethyl ester (CAPE) is found in a variety of plants and well-known the active ingredient of the honeybee propolis. CAPE showed anti-inflammatory, anticarcinogenic, antimitogenic, antiviral, and immunomodulatory properties in several studies.
Erdemli, Hacı Kemal, Akyol, Sumeyya, Armutcu, Ferah, Akyol, Omer   +3 more
openaire   +4 more sources

Effect of Propolis on PPP2R1A and Apoptosis in Cancer Cells

Biochemistry Research International, Volume 2025, Issue 1, 2025.
Recently, it has been shown that protein phosphatase 2A (PP2A) dysfunction was common in many cancer types and was mediated by various inactivation mechanisms. Although many research studies observed antitumor effect of propolis extracts in various types of cancer, the mechanism of effect are still obscure.
Burak Durmaz, Latife Merve Oktay Çelebi, Ayşe Çekin, Ayshan Ahadova, Nur Selvi Günel, Hatice Kalkan Yıldırım, Ali Mert Özgönül, Eser Yıldırım Sözmen, Aziz ur Rehman Aziz   +8 more
wiley   +1 more source

Effects of caffeic acid phenethyl ester on wound healing in calvarial defects

Acta Odontologica Scandinavica, 2014
The aim of this study is to analyze histologically the effect of CAPE on bone healing of Critical Size Defect (CSD) in rat calvaria.Thirty-two 3-month-old male rats were used. The animals were randomly divided into four groups. Group A received isotonic saline solution, Group B received CAPE (50 mmol/kg) locally, Group C received CAPE (100 mmol/kg ...
Kazancioglu, Hakki Oguz, Bereket, Mehmet Cihan, Ezirganli, Seref, Aydin, Mehmet Serif, Aksakalli, Sertac   +4 more
openaire   +5 more sources

The Potential of Secondary Metabolites in Medicinal Plants as Anti–Quorum Sensing in Biofilms: A Comprehensive Review

Journal of Chemistry, Volume 2025, Issue 1, 2025.
The formation of biofilms occurs due to a group of bacteria gathering together. The increasing of cell density will stimulate chemical signals for bacteria to communicate through quorum sensing system. Quorum sensing plays a role for competition, virulence, resistance, and pathogenesis. Quorum sensing produces signaling response called as autoinducers.
Salsabila Aqila Putri, Euis Julaeha, Natsuko Kagawa, Dikdik Kurnia, Senthilkumar Nangan   +4 more
wiley   +1 more source

Cathodoluminescent and Characteristic X‐Ray‐Emissive Rare‐Earth‐Doped Core/Shell Protein Labels for Spectromicroscopic Analysis of Cell Surface Receptors

Small, Volume 20, Issue 48, November 27, 2024.
Small (sub‐20 nm) lanthanide‐doped nanoparticles are successfully utilized in electron microscopy to label biological structures and contextualize them in the cell's ultrastructure. Leveraging unique energy‐dispersive X‐ray signatures, the nanoparticles' location and doping‐identity is easily and fast retrieved, demonstrating the methods' potential to (
Sebastian Habermann, Lukas R. H. Gerken, Mathieu Kociak, Christian Monachon, Vera M. Kissling, Alexander Gogos, Inge K. Herrmann   +6 more
wiley   +1 more source

Impact of Caffeic Acid Phenethyl Ester on Spinal Cord Inflammation in Mice Model of Multiple Sclerosis

Journal of Tropical Life Science
Since the majority of the current therapies lack effectiveness and efficiency in treating Multiple Sclerosis, in addition to their high cost, monitoring during usage, and the serious side effects associated with using this therapy, which in some cases ...
Amin Alnawajha, Agustina Endharti, Sanarto Santoso, Dewi Santosaningsih   +3 more
doaj   +1 more source

The Immunoregulatory Effects of Caffeic Acid Phenethyl Ester on the Cytokine Secretion of Peripheral Blood Mononuclear Cells From Asthmatic Children

Pediatrics and Neonatology, 2011
Asthma is a chronic inflammatory disease of the airways for which current treatments are mainly based on pharmacological interventions, such as glucocorticoid therapy.
Leticia Bautista Sy, Li-King Yang, Chiau-Juno Chiu, Wen-Mein Wu   +3 more
doaj   +1 more source