Results 11 to 20 of about 33,889 (177)

Prevalence of East Asian (East CagA) and Western variants of the cagA (Western cagA) gene of Helicobacter pylori in Yakutia

open access: yesЯкутский медицинский журнал, 2021
The results of studying the prevalence of East Asian and Western variants of the cagA gene among Helicobacter pylori strains in Yakutia are presented. In the studied sample of Helicobacter pylori (H. pylori) DNA samples isolated from biopsies of patients
N. N. Gotovtsev   +5 more
doaj   +2 more sources

Characterizing Helicobacter pylori cagA in Myanmar

open access: yesGut and Liver, 2018
Background/AimsDifferences in the Helicobacter pylori infection rate are not sufficient to clarify the dissimilarity of gastric cancer incidence between Myanmar and its neighboring countries. To better understand this trend, the H.
Thein Myint   +8 more
doaj   +5 more sources

Characterization of the cagA-gene in Helicobacter pylori in Mongolia and detection of two EPIYA-A enriched CagA types [PDF]

open access: yesInternational Journal of Medical Microbiology, 2022
Helicobacter pylori infection is strongly associated with gastritis, gastroduodenal ulcer disease and gastric carcinoma. The virulence of H. pylori strains increases with the presence of the pathogenicity island PAI, which encodes a Type 4 Secretion System and the oncoprotein CagA.
Oyunbaatar Altanbayar   +8 more
openaire   +7 more sources

Acid-Tolerance Response in Helicobacter pylori and Differences between cagA+ and cagA- Strains [PDF]

open access: yesJournal of Infectious Diseases, 1998
Helicobacter pylori cagA transcription and translation are maximal at pH 6 in stationary phase. The aim of this study was to determine whether H. pylori has an acid-tolerance response and whether that response is related to CagA expression, by investigating whether preexposure to pH 5 or 6 improved survival of cells subsequently exposed to pH 3.
M, Karita, M J, Blaser
openaire   +2 more sources

Exosomal CagA from Helicobacter pylori aggravates intestinal epithelium barrier dysfunction in chronic colitis by facilitating Claudin-2 expression

open access: yesGut Pathogens, 2022
Background The chronic infection with Helicobacter pylori (H. pylori), especially cytotoxin-associated gene A-positive (CagA+) strains, has been associated with various extragastric disorders.
Yinjie Guo   +9 more
doaj   +1 more source

Comparative Study between Helicobacter pylori East-Asian-Type with 39-bp Deletions

open access: yesBiomolecular and Health Science Journal, 2022
Introduction: CagA, an oncogenic virulence factor of Helicobacter pylori, may present with 39-bp deletions in the preepiya region of East-Asian strains resulting in a virulent genotype.
Faizah Sugiarto   +9 more
doaj   +1 more source

CagA: a role at last [PDF]

open access: yesGut, 2000
Many strains of Helicobacter pylori produce an immunogenic high molecular weight protein called cytotoxin associated gene product A (CagA) and infection with such strains can be detected by a simple serological test for anti-CagA antibodies. Numerous studies over the past nine years have shown that CagA positive infections are more likely than CagA ...
openaire   +2 more sources

Evaluation of the Anti-East Asian CagA-Specific Antibody for CagA Phenotyping

open access: yesClinical and Vaccine Immunology, 2009
ABSTRACT The determination of the cagA genotype is generally based on sequencing the variable 3′ region of the cagA gene. In a previous study, we successfully generated an anti-East Asian CagA-specific antibody (anti-EAS Ab) immunoreactive only with the East Asian CagA and not with ...
Lam Tung, Nguyen   +18 more
openaire   +2 more sources

Nitric oxide system in patients infected with Helicobacter pylori of different genotypes

open access: yesКлинический разбор в общей медицине, 2023
Introduction. Helicobacter pylori (Hp) is a class I biological carcinogen and the third leading cause of cancer death in the world, according to the World Health Organization.
Ekaterina Yu. Plotnikova   +2 more
doaj   +1 more source

Production of a Recombinant CagA Protein for the Detection of Helicobacter pylori CagA Antibodies

open access: yesMikrobiyoloji Bulteni, 2014
At present, Helicobacter pylori infections affect approximately 50% of the world population. It is known that H.pylori is related with several gastric diseases including chronic atrophic gastritis, peptic and gastric ulcers as well as gastric carcinomas.
Miray, Akgüç   +7 more
openaire   +2 more sources

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