Results 21 to 30 of about 33,889 (177)
Tyrosine Kinases in Helicobacter pylori Infections and Gastric Cancer
Toxins, 2019 Helicobacter pylori (H. pylori) has been identified as a leading cause of gastric cancer, which is one of the most frequent and malignant types of tumor.
Bianca E. Chichirau +3 more
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mBio, 2017 Infection with Helicobacter pylori is a major risk factor for development of gastric disease, including gastric cancer. Patients infected with H. pylori strains that express CagA are at even greater risk of gastric carcinoma. Given the importance of CagA,
Sungil Jang +14 more
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ROLUL HELICOBACTER PYLORI ÎN GENEZA PLURIFACTORIALÅ A ULCERULUI PEPTIC LA COPIL [PDF]
Romanian Journal of Pediatrics, 2010 Boala ulceroasă a copilului şi adolescentului constituie o preocupare constantă în gastroentrologia pediatrică atât prin prevalenţa şi incidenţa încă importante, cât şi prin implicarea unor mecanisme etiopatogenice diverse care determină nu numai ...
Smaranda Diaconescu, M. Burlea
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Toxins, 2017 Cytotoxin-associated gene product A (CagA) is a major virulence factor secreted by Helicobacter pylori. CagA activity in the gastric epithelium is associated with higher risk of gastric cancer development.
Abolghasem Tohidpour +3 more
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Cloning the CagA gene of Helicobacter pylori for the production of recombinant CagA protein
, 2021 H. pylori infection can lead to the development of peptic ulcer and gastric cancer. Several virulence factors were shown to play a role in the clinical outcome. Among these the cagA gene is one of the major factors involved in pathogenesis. The possession of cagA by certain strains appears to affect the clinical outcome.
openaire +3 more sources
Pathogens, 2022 Helicobacter pylori (Hp) is a grade Ι carcinogen of gastric cancer (GC), and its high infection rate seriously affects human health. Cytotoxin-associated gene A (CagA) plays a key role in the carcinogenesis of Hp as one of its main virulence factors. miR-
Leilei Wu, Fei Jiang, Xiaobing Shen
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Cloning and Expression of Helicobacter Pylori CagA Gene Antigenic Regions in E. coli [PDF]
Journal of Advanced Biomedical Sciences, 2016 Background & Objective: Helicobacter pylori, which has infected about 50 percent of the world population, is one of the most common gastrointestinal pathogens and the most prevalent cause of gastro-intestinal diseases, such as chronic gastric ulcers ...
Mahdye Maleki +3 more
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Novel CagA ELISA exhibits enhanced sensitivity ofHelicobacter pyloriCagA antibody
World Journal of Gastroenterology, 2017 To develop a novel Helicobacter pylori (H. pylori) CagA antibody enzyme-linked immunosorbent assay (ELISA) suitable for detecting serum anti-CagA antibodies with high sensitivity.Recombinant East Asian-type CagA protein was purified and immobilized for ELISA. Serum samples from 217 Vietnamese individuals (110 H.
Yuichi, Matsuo +13 more
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Biomolecular and Health Science Journal, 2023 Introduction: Helicobacter pylori (HP) has several important virulence factors including Cytotoxin-Associated Gene A (CagA). Studying the protein structure and physicochemical characteristics of CagA from the sequence data are essential to understand ...
Hamidah Kurniasari +7 more
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Risk for gastric cancer in people with CagA positive or CagA negative Helicobacter pylori infection. [PDF]
Gut, 1997 BACKGROUND AND AIMS: It is not known why some people with Helicobacter pylori infection develop gastric cancer whereas others do not. Whether the CagA phenotype of H pylori infection affected risk for cancer independently of other posited risk factors was evaluated.
J, Parsonnet +3 more
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