Results 101 to 110 of about 662,429 (302)
A contemporary simple risk score for prediction of severe AKI after HT. Abstract Background The aim of this study was to develop a simple risk score to estimate severe acute kidney injury (AKI) risk based on a large contemporary heart transplantation (HT) cohort.
Shuangshuang Zhu +10 more
wiley +1 more source
Calcineurin-NFAT signaling pathway.
Calcium-mediated signaling is involved in the activation of diverse subsets of gene transcription, including GZMB. Target gene expression can change with the activation of transcriptional factors in response to electrical stimulation, thus providing a ...
Minseon Lee (18404208) +1 more
core +1 more source
Sequeira et al. reveal how the glucagon‐like peptide‐1 receptor agonist (GLP‐1‐RA) semaglutide restores cardiomyocyte function in rats subjected to a high‐fat/high‐fructose diet (HFD). Employing fluorescence‐ and patch‐clamp technology in isolated cardiac myocytes, they demonstrate that semaglutide reverses HFD‐induced activation of L‐type calcium ...
Vasco Sequeira +12 more
wiley +1 more source
ATOPIC DERMATITIS: NEW ASPECTS OF TREATMENT
Atopic dermatitis is a chronic inflammatory cutaneous disease, which demands a prolonged treatment. A modern views on the main approaches to treatment of atopic dermatitis in children and adults are analyzed in this article. The treatment is based on the
D. Sh. Macharadze
doaj +1 more source
<b>Introduction:</b> Cardiac remodelling is controlled by complex systems, including activation of the renin-angiotensin system (RAS) and signalling through MAP kinases and Ca2+-activated calcineurin.
Touyz, R.M., Montezano, A.C., White, M.
core +1 more source
Untethered Electrical Stimulation Using Optoelectricity and Piezoelectricity for Tissue Regeneration
Untethered electrical stimulation from optoelectronic and piezoelectric materials can aid regeneration of damaged tissue. ABSTRACT Electrical signals are increasingly recognized as important regulators of tissue development and regeneration, with outcomes linked to behaviors including proliferation, differentiation, cell migration, and more.
Ryan Yao, Baochun Xu, Cunjiang Yu
wiley +1 more source
Fungal Morphology in Resistance to Calcineurin Inhibitors and Host - Pathogen Interactions
This item is available only to currently enrolled UTSA students, faculty or staff. To download, navigate to Log In in the top right-hand corner of this screen, then select Log in with my UTSA ID.Fungal dimorphism is the ability of a fungus to switch ...
Vellanki, Sandeep
core +1 more source
Myeloid leucocytes mediate host protection against infection and critically regulate inflammatory responses in body tissues. Pattern recognition receptor signalling is crucial for myeloid cell responses to pathogens, but growing evidence suggests an ...
Kamila Bendickova +2 more
doaj +1 more source
ABSTRACT Postoperative ileus (POI) is a frequent complication after surgical procedures, predominantly manifesting as aberrant gastrointestinal motility, which markedly extends the duration of postoperative recovery for patients. The clinical duration of POI is typically modulated by intricate inflammatory cascades, with mast cells assuming a critical ...
Tian‐le Zhang +4 more
wiley +1 more source
In silico binding affinity study of calcineurin inhibitors to calcineurin and its close associates
Calcineurin (CN) is a calcium regulated serine/threonine protein phosphatase. It is known to be inhibited by cyclosporin A (CsA), tacrolimus (FK506), endothall (ENDO), microcystin (MCYST), okadaic acid (OA) and trifluoperazine (TFP).
Devaraju, K.S. +6 more
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