Results 151 to 160 of about 662,429 (302)

Economic Burden and Treatment Patterns Among Patients Diagnosed With Vitiligo in Japan: An Observational Retrospective Cohort Study

The Journal of Dermatology, EarlyView.
ABSTRACT Vitiligo, a common and chronic depigmentation disorder, significantly impacts patients' quality of life and exerts a substantial economic burden. The deleterious impact of vitiligo can be exacerbated by comorbid conditions, including psychiatric and autoimmune conditions.
Naoki Oiso, Kent A. Hanson, Ahmed M. Soliman, Chao Li, Manabu Taura, Daniel Mercer, Andrew Rava, Danielle Bynoe, Haiyan Sun, Tamio Suzuki   +9 more
wiley   +1 more source

External Genital Cutaneous Sarcoidosis Mimicking Lichen Sclerosus

Australasian Journal of Dermatology, EarlyView.
ABSTRACT Although external genital cutaneous sarcoidosis is rare, it can closely resemble lichen sclerosus (LS) and delay diagnosis. We report a case of a 69‐year‐old woman with long‐standing vulvar symptoms and LS‐like pallor of the labia minora and clitoris. Biopsy showed non‐caseating granulomas with negative infection stains, consistent with vulvar
Enakshi Mudalige, Annabel Stevenson
wiley   +1 more source

The case for treatment of monogenic SRNS with calcineurin inhibitors. [PDF]

Kidney Int, 2023
Lane BM, Gbadegesin RA.
europepmc   +1 more source

The Impact of Common Medications on Male Fertility: An Updated Systematic Review

Andrology, EarlyView.
ABSTRACT Background Compared with those of cytotoxic treatments, the potential effects of common medications on the fertility of men trying to conceive currently or planning to conceive in the future are less well described. The use of common medications may modify the gonadotropic axis, spermatogenesis, and epididymal maturation or alter male ...
Lina Jebli, Salomé Gallissian, Roxanne Barèges, Félicia Fournier, Catherine Metzler‐Guillemain, Ségolène Prades, Fanny Magnan‐Sebag, Jeanne Perrin   +7 more
wiley   +1 more source

In silico binding affinity study of calcineurin inhibitors to calcineurin and its close associates

, 2013
213-217Calcineurin (CN) is a calcium regulated serine/threonine protein phosphatase. It is known to be inhibited by cyclosporin A (CsA), tacrolimus (FK506), endothall (ENDO), microcystin (MCYST), okadaic acid (OA) and trifluoperazine (TFP).
Devaraju, K S, Saraswathi, R, Gopi, A, Anushree, Babu, R L, Sharma, S Chidananda, Harish, B M   +6 more
core  

Lactate‐Responsive Glycogen Dynamics Are Associated With Bull Sperm Motility and Fertilization Under Glucose‐Limited Conditions

Andrology, EarlyView.
ABSTRACT Background Mammalian sperm need to undergo hyperactivation, capacitation, and acrosome reaction to achieve fertilization competence. However, the female reproductive tract presents contrasting metabolic environments. The uterus is glucose‐rich, and the oviduct is lactate‐rich and glucose‐limited.
Md Faizul Hossain Miraz, Takahiro Yamanaka, Takashi Umehara, Shahrina Akter, Wambugu Enoc Njoroge, Masayuki Shimada   +5 more
wiley   +1 more source

Topical Calcineurin Inhibitors in Rosacea: Potential Benefit in Selected Clinical Settings and Risk of Rosaceiform Dermatitis. [PDF]

Clin Cosmet Investig Dermatol
Liu T, Meng X, Chen N, Yang W, Li D, Xu Y.   +5 more
europepmc   +1 more source

Ibrutinib versus allogeneic haematopoietic stem cell transplant in relapsed/refractory del(17p) chronic lymphocytic leukaemia/small lymphocytic lymphoma

British Journal of Haematology, EarlyView.
After adjusting for confounders, the ibrutinib cohort had significantly better overall survival (adjusted hazard ratio, 0.39; 95% confidence interval, 0.23–0.68; p = 0.0008) than the allogeneic haematopoietic stem cell transplantation (alloHSCT) cohort.
Farrukh T. Awan, Ran Liu, Hsin‐Hui Huang, Matthew Bye, Kwang Woo Ahn, Gabriel Krigsfeld, Anat Raz, Heather Wolfe, Mehdi Hamadani   +8 more
wiley   +1 more source

Drug-Drug Interactions Between Oral Anticoagulants and Calcineurin Inhibitors in Nephrotic Syndrome for Management of Thromboembolism. [PDF]

Biomedicines
Hirai T, Katayama K.
europepmc   +1 more source

The Effect of Calcineurin Inhibitors on MMPs Activity in Heart and Their Side Effects-A Review of Literature. [PDF]

Int J Mol Sci, 2023
Surówka A, Prowans P, Żołnierczuk M, Miśkiewicz M, Wawrowski T, Skodda M, Markowska M, Kędzierska-Kapuza K.   +7 more
europepmc   +1 more source