Results 131 to 140 of about 97,221 (328)

Dynamics of the CD9 interactome during bacterial infection of epithelial cells by proximity labelling proteomics

The FEBS Journal, EarlyView.
We describe the CD9 interactome in epithelial cells for the first time. The interactome is diverse and dynamic and changes dependent on infection with specific bacteria. We validate these data by showing functional interaction between CD9 with CD44 or CD147. We therefore demonstrate that CD9 is a universal organiser of bacterial adhesion platforms able
Paige A. Wolverson, Isabel Fernandes Parreira, Ruth H. Thompson, Mark O. Collins, Jonathan G. Shaw, Luke R. Green   +5 more
wiley   +1 more source

A 52‐week open‐label extension study to evaluate the safety and efficacy of oral rimegepant for the preventive treatment of migraine

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective To assess the safety, tolerability, and treatment effects of rimegepant 75 mg every other calendar day (EOD) for the preventive treatment of migraine in a 52‐week, open‐label extension (OLE) study. Background Rimegepant is an oral small molecule calcitonin gene–related peptide receptor antagonist approved for the acute treatment of ...
David Kudrow, Robert S. Croop, Alexandra Thiry, Richard B. Lipton   +3 more
wiley   +1 more source

Expression of calcitonin gene-related peptide and pulp sensitivity tests in irreversible pulpitis

Brazilian Oral Research
The aim of the present study was to identify the relationship between the expression of calcitonin gene-related peptide (CGRP) and the responses of pulp sensitivity tests in healthy pulps and irreversible pulps by performing a cross-sectional study on ...
Brenda Eréndida CASTILLO-SILVA, Verónica MARTÍNEZ-JIMÉNEZ, Gabriel Alejandro MARTÍNEZ- CASTAÑÓN, Carlo Eduardo MEDINA-SOLÍS, Eva Concepción AGUIRRE-LÓPEZ, Jesús Ramón CASTILLO-HERNÁNDEZ, Nereyda NIÑO-MARTÍNEZ, Nuria PATIÑO-MARÍN   +7 more
doaj   +1 more source

Reduction of opioid and barbiturate use following initiation of rimegepant for migraine in the United States

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective The primary objective of this study was to evaluate opioid and barbiturate utilization before and after the first prescription of the calcitonin gene–related peptide receptor antagonist rimegepant in individuals with migraine. Background Although not recommended in migraine treatment guidelines, opioids and barbiturates are often ...
Noah Rosen, Aaron Jenkins, Karin Hygge Blakeman, Feng Dai, Lucy Abraham, Chelsea Leroue, Josh Brown   +6 more
wiley   +1 more source

Real-World Clinical Effectiveness and Migraine-Related Healthcare Resource Utilization in Patients Initiating Fremanezumab in Germany and the United Kingdom

Therapeutics and Clinical Risk Management
Axel Heinze,1 Shazia K Afridi,2 Todor I Totev,3 Lynda J Krasenbaum,4 Emi Terasawa,5 Hasan Akcicek,6 Joachim Hipp,7 Dalbir Dhiraj,8 Rochelle Sun,3 Erica Yim,5 Binyam Yilma,5 Maurice T Driessen9 1Migraine and Headache Center, Pain Clinic Kiel, Kiel ...
Heinze A, Afridi SK, Totev TI, Krasenbaum LJ, Terasawa E, Akcicek H, Hipp J, Dhiraj D, Sun R, Yim E, Yilma B, Driessen MT   +11 more
doaj  

Calcitonin Gene-Related Peptide (Cgrp), Adrenomedullin (Am), Amylin, And Calcitonin (Ct) Receptors And Overlapping Biological Actions

The Scientific World Journal, 2001
CGRP, AM, amylin, and CT have in common N-terminal 6-7 amino acid ring structures linked by disulfide bridges and amidated C-termini required for biological activity.
J.A. Fischer, W. Born, R. Muff
doaj   +1 more source

CGRP nuovo bersaglio farmacologico per il trattamento dell'emicrania [PDF]

, 2016
In questo lavoro di tesi sono state discusse varie classi di farmaci per il trattamento dell’emicrania, dai primi utilizzati fino agli studi più recenti.
ANDALORO, RACHELE
core  

The potential role of sleep quality in the relationship between glymphatic function and migraine frequency: Insights from a cross‐sectional study

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective This study aimed to explore the association between glymphatic function, as assessed by the diffusion tensor imaging along perivascular space (DTI‐ALPS) index, and headache frequency in individuals with migraine. Additionally, it evaluated whether sleep quality modulates this relationship.
Raffaele Ornello, Federico Salfi, Maria Grazia Vittorini, Antonio Innocenzi, Federico De Santis, Federico Bruno, Francesca Pistoia, Michele Ferrara, Alessandra Splendiani, Simona Sacco   +9 more
wiley   +1 more source

Calcitonin gene related peptide.

BMJ, 1991
D J, O'Halloran, S R, Bloom
openaire   +4 more sources

Changes in brainstem habituation during onabotulinumtoxinA treatment in chronic migraine: A prospective case–control study

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objectives/Background Chronic migraine is a debilitating neurological disorder characterized by central sensitization and impaired brainstem habituation. OnabotulinumtoxinA is an established prophylactic treatment for chronic migraine, yet its effects on central trigeminal sensory processing remain incompletely understood.
Gerlinde Freimark, Sebastian Strauss, Lucas H. Overeem, Mira P. Fitzek, Kristin S. Lange, Carolin L. Höhne, Uwe Reuter, Robert Fleischmann, Bianca Raffaelli   +8 more
wiley   +1 more source