Results 21 to 30 of about 770,107 (277)

CIB1 protects against MPTP-induced neurotoxicity through inhibiting ASK1. [PDF]

, 2017
Calcium and integrin binding protein 1 (CIB1) is a calcium-binding protein that was initially identified as a binding partner of platelet integrin αIIb. Although CIB1 has been shown to interact with multiple proteins, its biological function in the brain
Choi, Eui-Ju, Kang, Seongman, Kim, Yeonsil, Kim, Young Mok, Naik, Ulhas P., Parise, Leslie V., Sun, Woong, Yang, Hyun-Suk, Yoon, Kyoung Wan   +8 more
core   +4 more sources

Comparative evaluation of cannabinoid receptors, apelin and S100A6 protein in the heart of women of different age groups

BMC Cardiovascular Disorders, 2018
Background Recent studies have shown a significant role of the endocannabinoid system, apelin and S100A6 protein in the regulation of cardiovascular system functioning.
Irena Kasacka, Żaneta Piotrowska, Anna Filipek, Wojciech Lebkowski   +3 more
doaj   +1 more source

Calsequestrins in skeletal and cardiac muscle from adult Danio rerio [PDF]

, 2015
Calsequestrin (Casq) is a high capacity, low affinity Ca2+-binding protein, critical for Ca2+-buffering in cardiac and skeletal muscle sarcoplasmic reticulum. All vertebrates have multiple genes encoding for different Casq isoforms.
Argenton, Francesco, Furlan, Sandra, Mosole, Simone, Murgia, Marta, Nagaraj, Nagarjuna, Nori, Alessandra, Volpe, Pompeo   +6 more
core   +1 more source

Developmental and adult characterization of secretagogin expressing amacrine cells in zebrafish retina. [PDF]

PLoS ONE, 2017
Calcium binding proteins show stereotypical expression patterns within diverse neuron types across the central nervous system. Here, we provide a characterization of developmental and adult secretagogin-immunolabelled neurons in the zebrafish retina with
Stefanie Dudczig, Peter David Currie, Patricia Regina Jusuf   +2 more
doaj   +1 more source

Structural diversity of neuronal calcium sensor proteins and insights for activation of retinal guanylyl cyclase by GCAP1. [PDF]

, 2014
Neuronal calcium sensor (NCS) proteins, a sub-branch of the calmodulin superfamily, are expressed in the brain and retina where they transduce calcium signals and are genetically linked to degenerative diseases.
Ames, James B, Dizhoor, Alexander M, Lim, Sunghyuk   +2 more
core   +2 more sources

Characterization of the S100A1 protein binding site on TRPC6 C-terminus. [PDF]

PLoS ONE, 2013
The transient receptor potential (TRP) protein superfamily consists of seven major groups, among them the "canonical TRP" family. The TRPC proteins are calcium-permeable nonselective cation channels activated after the emptying of intracellular calcium ...
Jan Bily, Lenka Grycova, Blanka Holendova, Michaela Jirku, Hana Janouskova, Kristyna Bousova, Jan Teisinger   +6 more
doaj   +1 more source

Seminal Plasma Proteins [PDF]

, 2012
The ejaculated semen consists of two major components viz. sperm cells (spermatozoa) and the fluid part obtained after centrifugation called seminal plasma.
P Perumal
core   +2 more sources

Reviving lost binding sites: Exploring calcium‐binding site transitions between human and murine CD23

FEBS Open Bio, 2021
Immunoglobulin E (IgE) is a central regulatory and triggering molecule of allergic immune responses. IgE’s interaction with CD23 modulates both IgE production and functional activities.CD23 is a noncanonical immunoglobulin receptor, unrelated to ...
Veronica F. Ilkow, Anna M. Davies, Balvinder Dhaliwal, Andrew J. Beavil, Brian J. Sutton, James M. McDonnell   +5 more
doaj   +1 more source

Coarse-Grained Modeling and Molecular Dynamics Simulations of Ca2+-Calmodulin

Frontiers in Molecular Biosciences, 2021
Calmodulin (CaM) is a calcium-binding protein that transduces signals to downstream proteins through target binding upon calcium binding in a time-dependent manner.
Jules Nde, Jules Nde, Pengzhi Zhang, Jacob C. Ezerski, Wei Lu, Kaitlin Knapp, Peter G. Wolynes, Margaret S. Cheung, Margaret S. Cheung   +8 more
doaj   +1 more source

Calmodulin binding proteins and neuroinflammation in multiple neurodegenerative diseases

BMC Neuroscience, 2022
Calcium dysregulation (“Calcium Hypothesis”) is an early and critical event in Alzheimer’s and other neurodegenerative diseases. Calcium binds to and regulates the small regulatory protein calmodulin that in turn binds to and regulates several hundred ...
Danton H. O’Day, Robert J. Huber
doaj   +1 more source