Results 211 to 220 of about 30,912 (250)
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Calcium/calmodulin‐dependent serine protein kinase and mental retardation
Annals of Neurology, 2009AbstractCalcium/calmodulin‐dependent serine protein kinase (CASK) belongs to the membrane‐associated guanylate kinase protein family. The members of this protein family function as multiple domain adaptor proteins originally identified at cell junctions and synapses.
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Calcium-Calmodulin-Dependent Protein Kinase in Hyperplastic Human Parathyroid Glands
Endocrinology, 1987The function of the parathyroid gland is closely linked to intracellular and extracellular Ca2+ concentrations. As a step toward understanding the mechanism of action of Ca2+ on the parathyroid, we examined hyperplastic human parathyroid tissue for Ca2+ and calmodulin-dependent protein kinase activity.
B K, Kinder +3 more
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Involvement of calcium/calmodulin‐dependent protein kinase II in the induction of mPer1
Journal of Neuroscience Research, 2003AbstractRecent studies suggest that CaM kinase II is involved in light‐induced phase delays and induction of Per1 and Per2 genes in the hamster suprachiasmatic nucleus (SCN) (Yokota et al.,2001). We focused on intracellular mechanisms of the CaM kinase II‐induced mPer1 gene expression.
Kazumi, Nomura +4 more
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Calcium/calmodulin-dependent protein kinase II in human articular chondrocytes
Biorheology: The Official Journal of the International Society of Biorheology, 2006Mechanical stimuli are known to have major influences on chondrocyte function. The molecular events that regulate chondrocyte responses to mechanical stimulation have been the subject of much study. Using an in vitro experimental system we have identified mechanotransduction pathways that control molecular and biochemical responses of human articular ...
A, Shimazaki +4 more
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The Multifunctional Calcium/Calmodulin-Dependent Protein Kinase: From Form to Function
Annual Review of Physiology, 1995The regulation of cellular function by hormones and extracellular molecules, which bind to cell surface receptors, is initiated by signal transduction mech anisms at the plasma membrane that lead to the generation of intracellular signals, or second messengers.
A P, Braun, H, Schulman
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Calcium/Calmodulin Dependent Membrane Bound Protein Kinase
1986In recent years it has become apparent that the calcium ion plays a key regulatory role in plant cell metabolism. The details of the molecular events which contribute to this function are beginning to emerge. In animals it has been convincingly demonstrated that a common response to a variety of cell surface stimuli is a transient increase in ...
A. M. Hetherington +2 more
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Calcium/calmodulin-dependent protein kinase II: role in learning and memory
Molecular and Cellular Biochemistry, 1993Numerous studies over the past decade have established a role(s) for protein phosphorylation in modulation of synaptic efficiency. This article reviews this data and focuses on putative functions of Ca2+/calmodulin-dependent protein kinase II (CaM-kinase II) which is highly concentrated at these synapses which utilize glutamate as the neurotransmitter.
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Regulation and role of brain calcium/calmodulin-dependent protein kinase II
Neurochemistry International, 1992Ca2+/calmodulin-dependent protein kinase II (CaMKII) exhibits a broad substrate specificity and regulates diverse responses to physiological changes of intracellular Ca2+ concentrations. Five isozymic subunits of the highly abundant brain kinase are encoded by four distinct genes.
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Calcium/Calmodulin-Dependent Protein Kinases
2004J. Robison, Roger J. Colbran
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